NO851550L - Fremgangsmaate for fremstilling av imidazolderivater - Google Patents

Fremgangsmaate for fremstilling av imidazolderivater

Info

Publication number
NO851550L
NO851550L NO851550A NO851550A NO851550L NO 851550 L NO851550 L NO 851550L NO 851550 A NO851550 A NO 851550A NO 851550 A NO851550 A NO 851550A NO 851550 L NO851550 L NO 851550L
Authority
NO
Norway
Prior art keywords
preparing
procedure
imidazold
derivatives
imidazold derivatives
Prior art date
Application number
NO851550A
Other languages
English (en)
Other versions
NO162617B (no
NO162617C (no
Inventor
Albert Fischli
Anna Krasso
Henri Ramuz
Andre Szente
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO851550L publication Critical patent/NO851550L/no
Publication of NO162617B publication Critical patent/NO162617B/no
Publication of NO162617C publication Critical patent/NO162617C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/68—One oxygen atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO851550A 1984-04-19 1985-04-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske imidazolderivater. NO162617C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH196684 1984-04-19

Publications (3)

Publication Number Publication Date
NO851550L true NO851550L (no) 1985-10-21
NO162617B NO162617B (no) 1989-10-16
NO162617C NO162617C (no) 1990-01-24

Family

ID=4222776

Family Applications (1)

Application Number Title Priority Date Filing Date
NO851550A NO162617C (no) 1984-04-19 1985-04-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive tricykliske imidazolderivater.

Country Status (21)

Country Link
US (2) US4634710A (no)
EP (1) EP0163842A1 (no)
JP (1) JPS60233070A (no)
KR (1) KR850007256A (no)
AU (1) AU589555B2 (no)
CS (2) CS250249B2 (no)
DD (1) DD232277A5 (no)
DK (1) DK148585A (no)
ES (4) ES8607963A1 (no)
FI (1) FI851431A7 (no)
GR (1) GR850949B (no)
HU (1) HU193362B (no)
IL (1) IL74880A (no)
MC (1) MC1650A1 (no)
NO (1) NO162617C (no)
NZ (1) NZ211773A (no)
PH (1) PH21046A (no)
PT (1) PT80315B (no)
SU (2) SU1362402A3 (no)
ZA (1) ZA852765B (no)
ZW (1) ZW4585A1 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK337086A (da) * 1985-08-12 1987-02-13 Hoffmann La Roche Benzimidazolderivater
US5433959A (en) 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
US6749864B2 (en) 1986-02-13 2004-06-15 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
CA2195444A1 (en) * 1994-07-20 1996-02-01 Bernhard Kohl Thiopyridyl compounds for controlling helicobacter bacteria
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
AU2003254282A1 (en) * 2002-08-01 2004-02-23 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
PL2003130T3 (pl) * 2006-03-10 2012-04-30 Link Genomics Inc Nowa pochodna pirydyny o aktywności przeciwko helicobacter pylori
RU2487126C1 (ru) * 2011-11-28 2013-07-10 Открытое акционерное общество "Федеральный научно-производственный центр "Алтай" Способ получения 1,4-диоксан-2,3-диола

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1805548A1 (de) * 1968-10-26 1970-10-08 Agfa Gevaert Ag Benzimidazol-Derivate und ihre photographische Verwendung
IN148930B (no) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
HU193408B (en) * 1983-05-03 1987-10-28 Byk Gulden Lomberg Chem Fqb Process for production of new tree-cycle compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
AU589555B2 (en) 1989-10-19
PT80315B (en) 1987-03-16
ES551472A0 (es) 1987-06-01
ES8706128A1 (es) 1987-06-01
NO162617B (no) 1989-10-16
MC1650A1 (fr) 1986-04-07
ZA852765B (en) 1985-11-27
NO162617C (no) 1990-01-24
CS250248B2 (en) 1987-04-16
ES542370A0 (es) 1986-06-16
US4981861A (en) 1991-01-01
JPS60233070A (ja) 1985-11-19
ES551471A0 (es) 1987-06-01
HUT37613A (en) 1986-01-23
KR850007256A (ko) 1985-12-02
ES8706124A1 (es) 1987-06-01
AU4122885A (en) 1985-10-24
GR850949B (no) 1985-11-25
DD232277A5 (de) 1986-01-22
FI851431L (fi) 1985-10-20
FI851431A7 (fi) 1985-10-20
DK148585D0 (da) 1985-04-01
HU193362B (en) 1987-09-28
IL74880A (en) 1988-06-30
PT80315A (en) 1985-05-01
CS250249B2 (en) 1987-04-16
US4634710A (en) 1987-01-06
ES8706129A1 (es) 1987-06-01
FI851431A0 (fi) 1985-04-10
EP0163842A1 (de) 1985-12-11
ES551473A0 (es) 1987-06-01
NZ211773A (en) 1989-01-06
ZW4585A1 (en) 1985-11-20
DK148585A (da) 1985-10-20
SU1396965A3 (ru) 1988-05-15
PH21046A (en) 1987-07-03
IL74880A0 (en) 1985-07-31
SU1362402A3 (ru) 1987-12-23
ES8607963A1 (es) 1986-06-16

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