NO855241L - Fremgangsmaate til fremstilling av karbapenemforbindelser. - Google Patents

Fremgangsmaate til fremstilling av karbapenemforbindelser.

Info

Publication number
NO855241L
NO855241L NO855241A NO855241A NO855241L NO 855241 L NO855241 L NO 855241L NO 855241 A NO855241 A NO 855241A NO 855241 A NO855241 A NO 855241A NO 855241 L NO855241 L NO 855241L
Authority
NO
Norway
Prior art keywords
sup
compounds
carbapen
procedure
preparation
Prior art date
Application number
NO855241A
Other languages
English (en)
Other versions
NO163957B (no
NO163957C (no
Inventor
Yukio Sugimura
Toshihiko Hasimoto
Teruo Tanaka
Kimio Iino
Tomoyuki Shibata
Tetsuo Miyadera
Shinichi Sugawara
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO855241L publication Critical patent/NO855241L/no
Publication of NO163957B publication Critical patent/NO163957B/no
Publication of NO163957C publication Critical patent/NO163957C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Indole Compounds (AREA)
  • Lubricants (AREA)
  • Steroid Compounds (AREA)
NO855241A 1984-12-25 1985-12-23 Analogifremgangsmaate til fremstilling av terapeutisk aktive karbapenemforbindelser. NO163957C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28170084 1984-12-25

Publications (3)

Publication Number Publication Date
NO855241L true NO855241L (no) 1986-06-26
NO163957B NO163957B (no) 1990-05-07
NO163957C NO163957C (no) 1990-08-15

Family

ID=17642759

Family Applications (1)

Application Number Title Priority Date Filing Date
NO855241A NO163957C (no) 1984-12-25 1985-12-23 Analogifremgangsmaate til fremstilling av terapeutisk aktive karbapenemforbindelser.

Country Status (18)

Country Link
US (1) US4740507A (no)
EP (1) EP0186525B1 (no)
JP (1) JPS61275279A (no)
KR (1) KR930005332B1 (no)
CN (1) CN1014246B (no)
AT (1) ATE51624T1 (no)
AU (1) AU575232B2 (no)
CA (1) CA1254562A (no)
DE (1) DE3576957D1 (no)
DK (1) DK169384B1 (no)
ES (2) ES8706148A1 (no)
FI (1) FI81576C (no)
HU (1) HU196071B (no)
IE (1) IE58823B1 (no)
NO (1) NO163957C (no)
NZ (1) NZ214676A (no)
PH (1) PH25391A (no)
ZA (1) ZA859797B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd 1―置換カルバペネム―3―カルボン酸誘導体
JPS6426580A (en) * 1987-07-21 1989-01-27 Sankyo Co Production of carbapenem derivative
US5102877A (en) * 1989-04-28 1992-04-07 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
US5286721A (en) * 1990-10-15 1994-02-15 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
TW209220B (no) * 1991-11-27 1993-07-11 Manyu Seiyaku Kk
GB9202298D0 (en) * 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
GB9210096D0 (en) * 1992-05-11 1992-06-24 Fujisawa Pharmaceutical Co 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives and their preparation
JP2696807B2 (ja) * 1992-08-06 1998-01-14 田辺製薬株式会社 カルバペネム誘導体の製法
PL335048A1 (en) * 1997-02-07 2000-03-27 Kyoto Pharmaceutical Ind Carbapenemic compounds, thier usage and intermediate compounds used in their production
SK16382000A3 (sk) 1998-05-01 2001-05-10 Kyoto Pharmaceutical Industries, Ltd. Karbapénové deriváty, ich vyžitie a ich medziproduktové zlúčeniny
YU92003A (sh) * 2001-05-21 2006-05-25 Kyoto Pharmaceutical Industries Ltd. Karbapenem jedinjenje
GB0400382D0 (en) * 2004-01-09 2004-02-11 Glaxo Group Ltd Novel processes
WO2006087996A1 (ja) * 2005-02-15 2006-08-24 Shionogi & Co., Ltd. カルバペネム誘導体の製法およびその中間体結晶

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383946A (en) * 1980-03-27 1983-05-17 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
JPS5913757A (ja) * 1982-07-14 1984-01-24 Sankyo Co Ltd 3−メルカプトピロリジン誘導体及びその製法
JPS5916892A (ja) * 1982-07-19 1984-01-28 Sankyo Co Ltd カルバペネム−3−カルボン酸誘導体およびその製法
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
JPS59205379A (ja) * 1983-05-09 1984-11-20 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法

Also Published As

Publication number Publication date
KR860004892A (ko) 1986-07-14
IE58823B1 (en) 1993-11-17
ES8706148A1 (es) 1987-06-01
FI855128A0 (fi) 1985-12-20
DK604485A (da) 1986-06-26
US4740507A (en) 1988-04-26
ES8707535A1 (es) 1987-08-01
HUT39182A (en) 1986-08-28
AU575232B2 (en) 1988-07-21
DE3576957D1 (de) 1990-05-10
DK604485D0 (da) 1985-12-23
FI81576C (fi) 1990-11-12
EP0186525B1 (en) 1990-04-04
JPS61275279A (ja) 1986-12-05
EP0186525A1 (en) 1986-07-02
CN85109699A (zh) 1986-08-13
DK169384B1 (da) 1994-10-17
CA1254562A (en) 1989-05-23
ES557035A0 (es) 1987-08-01
NO163957B (no) 1990-05-07
ZA859797B (en) 1986-09-24
KR930005332B1 (ko) 1993-06-17
HU196071B (en) 1988-09-28
FI81576B (fi) 1990-07-31
FI855128L (fi) 1986-06-26
NO163957C (no) 1990-08-15
CN1014246B (zh) 1991-10-09
NZ214676A (en) 1988-06-30
AU5169985A (en) 1986-07-03
ATE51624T1 (de) 1990-04-15
PH25391A (en) 1991-06-03
IE853300L (en) 1986-06-25
ES550403A0 (es) 1987-06-01

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