NO881904L - PROCEDURE FOR SELECTIVE IMMUNOLOGICAL DETERMINATION OF INTACT PROCOLLAGEN PEPTID (TYPE III) AND PROCOLLAGEN (TYPE III) IN BODY LIQUID, AND AGENT FOR ITS IMPLEMENTATION. - Google Patents

PROCEDURE FOR SELECTIVE IMMUNOLOGICAL DETERMINATION OF INTACT PROCOLLAGEN PEPTID (TYPE III) AND PROCOLLAGEN (TYPE III) IN BODY LIQUID, AND AGENT FOR ITS IMPLEMENTATION.

Info

Publication number
NO881904L
NO881904L NO88881904A NO881904A NO881904L NO 881904 L NO881904 L NO 881904L NO 88881904 A NO88881904 A NO 88881904A NO 881904 A NO881904 A NO 881904A NO 881904 L NO881904 L NO 881904L
Authority
NO
Norway
Prior art keywords
procollagen
type iii
peptid
implementation
procedure
Prior art date
Application number
NO88881904A
Other languages
Norwegian (no)
Other versions
NO175639B (en
NO175639C (en
NO881904D0 (en
Inventor
Dietrich Brocks
Rupert Timpl
Original Assignee
Hoechst Ag
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Max Planck Gesellschaft filed Critical Hoechst Ag
Publication of NO881904D0 publication Critical patent/NO881904D0/en
Publication of NO881904L publication Critical patent/NO881904L/en
Publication of NO175639B publication Critical patent/NO175639B/no
Publication of NO175639C publication Critical patent/NO175639C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Tires In General (AREA)
  • Agricultural Machines (AREA)
  • Lifting Devices For Agricultural Implements (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

It is possible by immunising animals with a peptide of the sequence I-C-E-S-C-P-T-G-G-Q-N-Y-S-P bound to an immunogenic protein to raise antibodies which can be used to determine procollagen peptide (type III) and procollagen type III selectively in body fluids.
NO881904A 1987-05-02 1988-04-29 Peptide, antibody obtained by the peptide, a method for immunologically determining intact procollagen peptide (type III) and use of the peptide NO175639C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873714634 DE3714634A1 (en) 1987-05-02 1987-05-02 METHOD FOR SELECTIVE IMMUNOLOGICAL DETERMINATION OF INTACT PROCOLLAGEN PEPTIDE (TYPE III) AND PROCOLLAGEN (TYPE III) IN BODY LIQUIDS AND MEANS TO IMPLEMENT IT

Publications (4)

Publication Number Publication Date
NO881904D0 NO881904D0 (en) 1988-04-29
NO881904L true NO881904L (en) 1988-11-03
NO175639B NO175639B (en) 1994-08-01
NO175639C NO175639C (en) 1994-11-09

Family

ID=6326686

Family Applications (1)

Application Number Title Priority Date Filing Date
NO881904A NO175639C (en) 1987-05-02 1988-04-29 Peptide, antibody obtained by the peptide, a method for immunologically determining intact procollagen peptide (type III) and use of the peptide

Country Status (10)

Country Link
EP (1) EP0298210B1 (en)
JP (1) JPH0780913B2 (en)
AT (1) ATE98377T1 (en)
DE (2) DE3714634A1 (en)
DK (1) DK168872B1 (en)
ES (1) ES2061545T3 (en)
FI (1) FI95579C (en)
IE (1) IE63385B1 (en)
NO (1) NO175639C (en)
PT (1) PT87375B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010862A (en) * 1987-11-06 2000-01-04 Washington Research Foundation Methods of detecting collagen type III degradation in vivo
DE4225038C2 (en) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Production and use of antibodies against collagen
EP0711415B1 (en) * 1993-07-28 1998-07-22 Boehringer Mannheim Gmbh Immunoassay for detecting collagen type i or collagen fragments thereof
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
WO1996012193A1 (en) 1994-10-17 1996-04-25 Osteometer Bio Tech A/S Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
ES2160985T3 (en) 1996-12-09 2001-11-16 Osteometer Biotech As SANDWICH TYPE TESTS FOR COLLAGEN FRAGMENTS.
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
EP1086135B1 (en) 1998-05-28 2004-02-25 Bayer HealthCare AG "monoclonal anitbody and assay for detecting n-terminal procollagen (iii) propeptide (piiinp)"
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2816841A1 (en) * 1978-04-18 1979-10-31 Max Planck Gesellschaft RADIOIMMUNOLOGICAL DETERMINATION OF PROCOLLAGEN (TYPE III) AND PROCOLLAGEN PEPTIDE (TYPE III)
DE3209149A1 (en) * 1982-03-13 1983-10-06 Hoechst Ag METHOD FOR THE COMMON IMMUNOLOGICAL DETERMINATION OF PROCOLLAGEN PEPTIDE (TYPE III) AND PROCOLLAGEN PEPTIDE COL 1 (TYPE III) AND METHOD FOR THE PRODUCTION OF ANTI-PROCOLLAGEN PEPTIDE COL 1 (TYPE III) SERUM

Also Published As

Publication number Publication date
EP0298210B1 (en) 1993-12-08
EP0298210A2 (en) 1989-01-11
IE63385B1 (en) 1995-04-19
NO175639B (en) 1994-08-01
JPH0780913B2 (en) 1995-08-30
ATE98377T1 (en) 1993-12-15
FI95579C (en) 1996-02-26
EP0298210A3 (en) 1991-05-15
FI882018A0 (en) 1988-04-29
DE3886109D1 (en) 1994-01-20
DK232988A (en) 1988-11-03
DK232988D0 (en) 1988-04-28
ES2061545T3 (en) 1994-12-16
FI882018L (en) 1988-11-03
PT87375A (en) 1989-05-31
NO175639C (en) 1994-11-09
IE881289L (en) 1988-11-02
DK168872B1 (en) 1994-06-27
FI95579B (en) 1995-11-15
JPS63292061A (en) 1988-11-29
PT87375B (en) 1992-08-31
DE3714634A1 (en) 1988-11-17
NO881904D0 (en) 1988-04-29

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Free format text: LAPSED IN OCTOBER 2002