NO884474L - Implanterbart, biologisk nedbrytbart virkestoff-frigjoeringssystem. - Google Patents

Implanterbart, biologisk nedbrytbart virkestoff-frigjoeringssystem.

Info

Publication number: NO884474L
Authority: NO; Norway
Prior art keywords: implant; active substance; release system; substance release; biological degradable
Prior art date: 1987-10-09

Application number

NO88884474A

Other languages

English (en)

Other versions

NO176304C (no

NO884474D0 (no

NO176304B (no

Inventor

Herbert Stricker

Guenther Entenmann

Otto Kern

Michel Mikhail

Bernd Zierenberg

Original Assignee

Boehringer Ingelheim Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-09

Filing date

1988-10-07

Publication date

1989-04-10

1988-10-07 Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg

1988-10-07 Publication of NO884474D0 publication Critical patent/NO884474D0/no

1989-04-10 Publication of NO884474L publication Critical patent/NO884474L/no

1994-12-05 Publication of NO176304B publication Critical patent/NO176304B/no

1995-03-22 Publication of NO176304C publication Critical patent/NO176304C/no

Links

239000013543 active substance Substances 0.000 title 1
239000007943 implant Substances 0.000 title 1
239000012876 carrier material Substances 0.000 abstract 2
JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 abstract 1
239000000654 additive Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000004014 plasticizer Substances 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1
239000011148 porous material Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Medicinal Preparation (AREA)
Materials For Medical Uses (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Adhesives Or Adhesive Processes (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Prostheses (AREA)

NO884474A 1987-10-09 1988-10-07 Fremgangsmåte for fremstilling av farmasöytiske implantater på basis av polylaktid NO176304C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19873734223 DE3734223A1 (de)	1987-10-09	1987-10-09	Implantierbares, biologisch abbaubares wirkstofffreigabesystem

Publications (4)

Publication Number	Publication Date
NO884474D0 NO884474D0 (no)	1988-10-07
NO884474L true NO884474L (no)	1989-04-10
NO176304B NO176304B (no)	1994-12-05
NO176304C NO176304C (no)	1995-03-22

Family

ID=6338006

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO884474A NO176304C (no)	1987-10-09	1988-10-07	Fremgangsmåte for fremstilling av farmasöytiske implantater på basis av polylaktid

Country Status (17)

Country	Link
EP (1)	EP0311065B1 (no)
JP (1)	JP2763303B2 (no)
KR (1)	KR970006082B1 (no)
AT (1)	ATE101035T1 (no)
AU (1)	AU609194B2 (no)
CA (1)	CA1333770C (no)
DE (2)	DE3734223A1 (no)
DK (1)	DK175252B1 (no)
ES (1)	ES2061589T3 (no)
FI (1)	FI100302B (no)
IE (1)	IE62505B1 (no)
IL (1)	IL87973A (no)
NO (1)	NO176304C (no)
NZ (1)	NZ226514A (no)
PH (1)	PH30236A (no)
PT (1)	PT88703B (no)
ZA (1)	ZA887535B (no)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2209937B (en) *	1987-09-21	1991-07-03	Depiopharm S A	Water insoluble polypeptides
US5424346A (en) *	1988-08-08	1995-06-13	Ecopol, Llc	Biodegradable replacement of crystal polystyrene
US6323307B1 (en)	1988-08-08	2001-11-27	Cargill Dow Polymers, Llc	Degradation control of environmentally degradable disposable materials
US5252642A (en) *	1989-03-01	1993-10-12	Biopak Technology, Ltd.	Degradable impact modified polyactic acid
US5180765A (en) *	1988-08-08	1993-01-19	Biopak Technology, Ltd.	Biodegradable packaging thermoplastics from lactides
US5444113A (en) *	1988-08-08	1995-08-22	Ecopol, Llc	End use applications of biodegradable polymers
US5216050A (en) *	1988-08-08	1993-06-01	Biopak Technology, Ltd.	Blends of polyactic acid
US5702716A (en) *	1988-10-03	1997-12-30	Atrix Laboratories, Inc.	Polymeric compositions useful as controlled release implants
DK0476045T3 (da) *	1989-06-05	1996-09-16	Massachusetts Inst Technology	Bionedbrydelige polymerer til lægemiddel-afgivelse i knogler
US5487897A (en)	1989-07-24	1996-01-30	Atrix Laboratories, Inc.	Biodegradable implant precursor
CH679207A5 (no) *	1989-07-28	1992-01-15	Debiopharm Sa
US5439688A (en) *	1989-07-28	1995-08-08	Debio Recherche Pharmaceutique S.A.	Process for preparing a pharmaceutical composition
AU651084B2 (en) *	1990-01-30	1994-07-14	Akzo N.V.	Article for the controlled delivery of an active substance, comprising a hollow space fully enclosed by a wall and filled in full or in part with one or more active substances
EP0447719B1 (en) *	1990-03-05	1993-11-03	Minnesota Mining And Manufacturing Company	Device for extended delivery of pharmacologically active agents to the ear
US5350580A (en) *	1990-03-05	1994-09-27	Minnesota Mining And Manufacturing Company	Device and method for extended delivery of pharmacologically active agents to the ear
AU2605592A (en) *	1991-10-15	1993-04-22	Atrix Laboratories, Inc.	Polymeric compositions useful as controlled release implants
US5681873A (en) *	1993-10-14	1997-10-28	Atrix Laboratories, Inc.	Biodegradable polymeric composition
US5605696A (en) *	1995-03-30	1997-02-25	Advanced Cardiovascular Systems, Inc.	Drug loaded polymeric material and method of manufacture
US5869079A (en)	1995-06-02	1999-02-09	Oculex Pharmaceuticals, Inc.	Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
CA2284575C (en) *	1997-04-04	2004-12-14	Alcan International Limited	Aluminum alloy composition and method of manufacture
AR012448A1 (es) *	1997-04-18	2000-10-18	Ipsen Pharma Biotech	Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada
US6261583B1 (en)	1998-07-28	2001-07-17	Atrix Laboratories, Inc.	Moldable solid delivery system
US6143314A (en) *	1998-10-28	2000-11-07	Atrix Laboratories, Inc.	Controlled release liquid delivery compositions with low initial drug burst
DE19908753C2 (de) *	1999-02-20	2003-10-02	Jenapharm Gmbh	Bioabbaubare, injizierbare Oligomer-Polymer-Zusammensetzung
US6306425B1 (en) *	1999-04-09	2001-10-23	Southern Research Institute	Injectable naltrexone microsphere compositions and their use in reducing consumption of heroin and alcohol
US8226598B2 (en)	1999-09-24	2012-07-24	Tolmar Therapeutics, Inc.	Coupling syringe system and methods for obtaining a mixed composition
US6702849B1 (en)	1999-12-13	2004-03-09	Advanced Cardiovascular Systems, Inc.	Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers
WO2001070846A1 (fr)	2000-03-22	2001-09-27	Dainippon Ink And Chemicals, Inc.	Antichoc et composition polyester contenant ledit antichoc
EP1637126B1 (en) *	2000-07-05	2016-12-14	Allergan, Inc.	Methods for treating inflammation of the eye
US6726918B1 (en)	2000-07-05	2004-04-27	Oculex Pharmaceuticals, Inc.	Methods for treating inflammation-mediated conditions of the eye
AU2002236495B2 (en)	2000-11-29	2006-05-11	Allergan, Inc.	Intraocular implants for preventing transplant rejection in the eye
US20050048099A1 (en)	2003-01-09	2005-03-03	Allergan, Inc.	Ocular implant made by a double extrusion process
US20050101582A1 (en)	2003-11-12	2005-05-12	Allergan, Inc.	Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en)	2003-11-12	2007-09-27	Lyons Robert T	Low immunogenicity corticosteroid compositions
EP1706095B1 (en)	2004-01-20	2008-12-24	Allergan, Inc.	Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
US8425929B2 (en)	2004-04-30	2013-04-23	Allergan, Inc.	Sustained release intraocular implants and methods for preventing retinal dysfunction
US20050244458A1 (en)	2004-04-30	2005-11-03	Allergan, Inc.	Sustained release intraocular implants and methods for treating ocular neuropathies
US20050244463A1 (en)	2004-04-30	2005-11-03	Allergan, Inc.	Sustained release intraocular implants and methods for treating ocular vasculopathies
US7799336B2 (en)	2004-04-30	2010-09-21	Allergan, Inc.	Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8722097B2 (en)	2004-04-30	2014-05-13	Allergan, Inc.	Oil-in-water method for making polymeric implants containing a hypotensive lipid
US8147865B2 (en)	2004-04-30	2012-04-03	Allergan, Inc.	Steroid-containing sustained release intraocular implants and related methods
US7771742B2 (en)	2004-04-30	2010-08-10	Allergan, Inc.	Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US8119154B2 (en)	2004-04-30	2012-02-21	Allergan, Inc.	Sustained release intraocular implants and related methods
US20050244469A1 (en)	2004-04-30	2005-11-03	Allergan, Inc.	Extended therapeutic effect ocular implant treatments
US8512738B2 (en)	2004-04-30	2013-08-20	Allergan, Inc.	Biodegradable intravitreal tyrosine kinase implants
US7993634B2 (en)	2004-04-30	2011-08-09	Allergan, Inc.	Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US9498457B2 (en)	2004-04-30	2016-11-22	Allergan, Inc.	Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US8591885B2 (en)	2004-04-30	2013-11-26	Allergan, Inc.	Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
ES2402376T3 (es) *	2006-04-06	2013-05-03	Nupathe Inc.	Implantes para el tratamiento de estados asociados con dopamina
US8802128B2 (en)	2006-06-23	2014-08-12	Allergan, Inc.	Steroid-containing sustained release intraocular implants and related methods
US8969415B2 (en)	2006-12-01	2015-03-03	Allergan, Inc.	Intraocular drug delivery systems
US8956641B2 (en) *	2008-04-18	2015-02-17	Warsaw Orthopedic, Inc.	Alpha adrenergic receptor agonists for treatment of inflammatory diseases
US8889173B2 (en) *	2008-04-18	2014-11-18	Warsaw Orthopedic, Inc.	Alpha adrenergic receptor agonists for treatment of pain and/or inflammation
US10588855B2 (en)	2008-05-12	2020-03-17	University Of Utah Research Foundation	Intraocular drug delivery device and associated methods
US9877973B2 (en)	2008-05-12	2018-01-30	University Of Utah Research Foundation	Intraocular drug delivery device and associated methods
PH12012500928A1 (en)	2009-11-09	2012-11-26	Allergan Inc	Compositions and methods for stimulating hair growth
JP4779169B1 (ja) *	2010-10-27	2011-09-28	Ｎｅｃインフロンティア株式会社	ボタン照明構造、電子機器
CN109602691A (zh)	2013-02-15	2019-04-12	阿勒根公司	持续药物递送植入物
GB201505527D0 (en)	2015-03-31	2015-05-13	Jmedtech Pte Ltd	Composition
WO2019071245A1 (en)	2017-10-06	2019-04-11	Foundry Therapeutics, Inc.	IMPLANTABLE DEPOSITS FOR REGULATED RELEASE OF ANALGESICS TO TREAT POSTHOPERATIVE PAIN ASSOCIATED WITH ORTHOPEDIC SURGERY, AND RELATED DEVICES, SYSTEMS, AND METHODS
WO2019136490A1 (en)	2018-01-08	2019-07-11	Foundry Therapeutics, Inc.	Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents
EP3793536A1 (en)	2018-05-12	2021-03-24	Foundry Therapeutics, Inc.	Implantable polymer depots for the controlled release of therapeutic agents
US12303619B2 (en)	2018-08-28	2025-05-20	Foundry Therapeutics, Inc.	Polymer implants

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE564759A (no) *	1955-12-22
US3755558A (en) *	1971-02-23	1973-08-28	Du Pont	Polylactide drug mixtures for topical application atelet aggregation
DE3218150C2 (de) *	1982-05-14	1986-09-25	Akzo Gmbh, 5600 Wuppertal	Wirkstoff enthaltender Körper für die Langzeitabgabe sowie Verfahren zu dessen Herstellung
US4962091A (en) *	1986-05-23	1990-10-09	Syntex (U.S.A.) Inc.	Controlled release of macromolecular polypeptides
US4758435A (en) *	1986-08-11	1988-07-19	American Cyanamid Company	Estradiol implant composition and method for preparation
DE3710175A1 (de) *	1987-02-12	1988-08-25	Hoechst Ag	Mehrteilige implantierbare arzneizubereitung mit langzeitwirkung

1987
- 1987-10-09 DE DE19873734223 patent/DE3734223A1/de not_active Withdrawn
1988
- 1988-10-06 EP EP88116522A patent/EP0311065B1/de not_active Expired - Lifetime
- 1988-10-06 AT AT88116522T patent/ATE101035T1/de not_active IP Right Cessation
- 1988-10-06 ES ES88116522T patent/ES2061589T3/es not_active Expired - Lifetime
- 1988-10-06 DE DE88116522T patent/DE3887616D1/de not_active Expired - Lifetime
- 1988-10-07 IE IE304088A patent/IE62505B1/en not_active IP Right Cessation
- 1988-10-07 PT PT88703A patent/PT88703B/pt not_active IP Right Cessation
- 1988-10-07 CA CA000579561A patent/CA1333770C/en not_active Expired - Lifetime
- 1988-10-07 NO NO884474A patent/NO176304C/no not_active IP Right Cessation
- 1988-10-07 IL IL87973A patent/IL87973A/xx active Protection Beyond IP Right Term
- 1988-10-07 FI FI884604A patent/FI100302B/fi not_active IP Right Cessation
- 1988-10-07 JP JP63253600A patent/JP2763303B2/ja not_active Expired - Lifetime
- 1988-10-07 AU AU23522/88A patent/AU609194B2/en not_active Expired
- 1988-10-07 ZA ZA887535A patent/ZA887535B/xx unknown
- 1988-10-07 PH PH37650A patent/PH30236A/en unknown
- 1988-10-07 DK DK198805615A patent/DK175252B1/da active
- 1988-10-08 KR KR1019880013156A patent/KR970006082B1/ko not_active Expired - Lifetime
- 1988-10-10 NZ NZ226514A patent/NZ226514A/xx unknown

Also Published As

Publication number	Publication date
JPH02117A (ja)	1990-01-05
DK561588D0 (da)	1988-10-07
DK561588A (da)	1989-04-10
NO176304C (no)	1995-03-22
CA1333770C (en)	1995-01-03
ATE101035T1 (de)	1994-02-15
NO884474D0 (no)	1988-10-07
ZA887535B (en)	1990-06-27
ES2061589T3 (es)	1994-12-16
EP0311065B1 (de)	1994-02-02
DK175252B1 (da)	2004-07-19
FI884604L (fi)	1989-04-10
IL87973A0 (en)	1989-03-31
IE62505B1 (en)	1995-02-08
FI884604A0 (fi)	1988-10-07
KR890006222A (ko)	1989-06-12
PT88703B (pt)	1992-12-31
AU609194B2 (en)	1991-04-26
DE3887616D1 (de)	1994-03-17
JP2763303B2 (ja)	1998-06-11
PT88703A (pt)	1988-11-01
EP0311065A1 (de)	1989-04-12
NZ226514A (en)	1990-02-26
IL87973A (en)	1992-08-18
FI100302B (fi)	1997-11-14
NO176304B (no)	1994-12-05
IE883040L (en)	1989-04-09
DE3734223A1 (de)	1989-04-20
KR970006082B1 (ko)	1997-04-23
PH30236A (en)	1997-02-05
AU2352288A (en)	1989-04-13

Legal Events

Date	Code	Title	Description
2008-10-20	MK1K	Patent expired

Publication	Publication Date	Title
NO884474D0 (no)	1988-10-07	Implanterbart, biologisk nedbrytbart virkestoff-frigjoeringssystem.
DE3850823D1 (de)	1994-09-01	System zur Freisetzung von Medikamenten und dessen Herstellungsmethode.
DE69434963D1 (de)	2007-06-14	Selektiv auf die leber wirkende pharmazeutisch aktive substanz
FI872481A0 (fi)	1987-06-03	Kiinteä, hallitusti vapauttava lääkeaineen kantoaineena käytettävä matriisi
DE69019817D1 (de)	1995-07-06	Trägermaterial zur Arzneimittelverabreichung.
ATE222500T1 (de)	2002-09-15	Enythropoietin enthaltendes arzneimittelabgabesystem
NZ221484A (en)	1991-01-29	Starburst polymer conjugates as carriers for agricultural, pharmaceutical and other materials
DK0839525T3 (da)	2004-11-29	Præparat med forlænget frigivelse
NZ221390A (en)	1990-10-26	Biodegradable implant containing estradiol and poly(lactide-co-glycolide) polymer: method of administration and preparation
DE3780218D1 (de)	1992-08-13	Tumor-nekrose-faktor-formulierung und ihre herstellung.
DK305087A (da)	1987-12-17	Buprenorphinholdigt farmaceutisk suppositorium
DK330787A (da)	1987-12-27	Stabiliseret farmaceutisk sammensaetning
ATE94764T1 (de)	1993-10-15	Nasal applizierbares arzneimittel, verfahren zu seiner herstellung und seine verwendung.
ATE90205T1 (de)	1993-06-15	Wasserunloesliche cytokine.
ATE85213T1 (de)	1993-02-15	Einen wirkstoff und ein in wasser quellendes polymer enthaltendes arzneimittel.
EP0380989A3 (en)	1990-12-12	Plaster for transdermal administration
ATE106718T1 (de)	1994-06-15	Perorale arzneimittelzubereitung mit verzögerter wirkstofffreigabe.
DE69003466D1 (de)	1993-10-28	Substituierte Thienopyrimidin-Derivate, deren Herstellung, pharmazeutische Zusammensetzungen und medizinische Verwendung.
DE69228031D1 (de)	1999-02-11	Ch0ndromodulin-II Protein
FR2605223B1 (fr)	1989-09-22	Compositions therapeutiques stables a base d' huile vegetale hydrophobe et son procede de preparation