NO885092L - Inhibitorer for faktor viii-hemmere. - Google Patents

Inhibitorer for faktor viii-hemmere.

Info

Publication number
NO885092L
NO885092L NO88885092A NO885092A NO885092L NO 885092 L NO885092 L NO 885092L NO 88885092 A NO88885092 A NO 88885092A NO 885092 A NO885092 A NO 885092A NO 885092 L NO885092 L NO 885092L
Authority
NO
Norway
Prior art keywords
amino acid
factor viii
residues
acid residues
fragment
Prior art date
Application number
NO88885092A
Other languages
English (en)
Norwegian (no)
Other versions
NO885092D0 (no
Inventor
Theodore S Zimmerman
Carol A Fulcher
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of NO885092D0 publication Critical patent/NO885092D0/no
Publication of NO885092L publication Critical patent/NO885092L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO88885092A 1987-11-16 1988-11-15 Inhibitorer for faktor viii-hemmere. NO885092L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12121787A 1987-11-16 1987-11-16

Publications (2)

Publication Number Publication Date
NO885092D0 NO885092D0 (no) 1988-11-15
NO885092L true NO885092L (no) 1989-05-18

Family

ID=22395296

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88885092A NO885092L (no) 1987-11-16 1988-11-15 Inhibitorer for faktor viii-hemmere.

Country Status (8)

Country Link
EP (1) EP0321094A3 (fr)
JP (1) JPH01221393A (fr)
KR (1) KR890008172A (fr)
AU (1) AU2473388A (fr)
DK (1) DK637288A (fr)
FI (1) FI885302A7 (fr)
IL (1) IL88310A0 (fr)
NO (1) NO885092L (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
MX350293B (es) * 2004-11-12 2017-09-04 Bayer Healthcare Llc Modificacion dirigida al sitio del factor viii.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649132A (en) * 1983-03-31 1987-03-10 Scripps Clinic And Research Foundation Treatment of Factor VIII inhibitors
DK525384D0 (da) * 1984-11-05 1984-11-05 Nordisk Insulinlab Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat

Also Published As

Publication number Publication date
EP0321094A3 (fr) 1990-03-07
FI885302A0 (fi) 1988-11-16
AU2473388A (en) 1989-06-22
IL88310A0 (en) 1989-06-30
DK637288A (da) 1989-05-17
FI885302L (fi) 1989-05-17
EP0321094A2 (fr) 1989-06-21
DK637288D0 (da) 1988-11-15
NO885092D0 (no) 1988-11-15
KR890008172A (ko) 1989-07-10
JPH01221393A (ja) 1989-09-04
FI885302A7 (fi) 1990-05-17

Similar Documents

Publication Publication Date Title
US4749780A (en) Biologically active fragments of human antihemophilic factor and method for preparation thereof
US4649132A (en) Treatment of Factor VIII inhibitors
Schreiber et al. Inhibition by CāINH of Hageman Factor Fragment Activation of Coagulation, Fibrinolysis, and Kinin Generation
Müller-Eberhard et al. Isolation of the anticomplementary protein from cobra venom and its mode of action on C3
Kloczewiak et al. Localization of a site interacting with human platelet receptor on carboxy-terminal segment of human fibrinogen γ chain
US5336610A (en) Method for purification of the zymogen of protein C or the heavy chain thereof using monoclonal antibody HPC-4
US8703429B2 (en) Composition exhibiting a von Willebrand Factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
Budzko et al. Cleavage of the fourth component of human complement (C4) by C1 esterase: isolation and characterization of the low molecular weight product
Nakayasu et al. Studies on human kininogens I. Isolation, characterization, and cleavage by plasma kallikrein of high molecular weight (HMW)-kininogen
EP0294025B1 (fr) Peptides correspondant au domaine de liaison au facteur VIII, du facteur de von Willebrand
EP0407544B1 (fr) Anticorps monoclonal dirige contre la proteine c
DK162233B (da) Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
Reber et al. Three abnormal fibrinogen variants with the same amino acid substitution (γ 275 Arg→ His): Fibrinogens Bergamo II, Essen and Perugia
JPH0829089B2 (ja) フアクタ−▲viii▼凝固因子ポリペプチド類
Shigeharu et al. Purification and characterization of a macromolecular weight cofactor for C3b-inactivator, C4bC3bINA-cofactor, of human plasma
Abraham et al. Purification and properties of a human plasma endogenous modulator for the platelet tricyclic binding/serotonin transport complex
US4831119A (en) Preparation for the treatment of hemophilia A inhibitor patients and a process for producing such a preparation
JP2001513762A (ja) 高度に精製されたvWFまたは因子VIII/vWF複合体を得る方法
EP0319315A2 (fr) Domaine du facteur VIII liant le facteur de von Willebrand
US4769336A (en) Treatment of factor VIII inhibitors
NO885092L (no) Inhibitorer for faktor viii-hemmere.
CZ211299A3 (cs) Derivát von Willebrandova faktoru, zařízení tento derivát obsahující a způsob isolace proteinů
DIMARCHI et al. Solid phase synthesis of the protected 43–55 tridecapeptide of the heavy chain of myeloma immunoglobin M603, employing cyclohexyl ester protection for glutamic acid
JPH01221396A (ja) 8因子の精製に使用するペプチド
JPH1192497A (ja) ペプチド及びその用途