NO891835L - Prodrug-former av 2',3'-didehydro-2',3'-dideoksy-nukleosider. - Google Patents

Prodrug-former av 2',3'-didehydro-2',3'-dideoksy-nukleosider.

Info

Publication number
NO891835L
NO891835L NO89891835A NO891835A NO891835L NO 891835 L NO891835 L NO 891835L NO 89891835 A NO89891835 A NO 89891835A NO 891835 A NO891835 A NO 891835A NO 891835 L NO891835 L NO 891835L
Authority
NO
Norway
Prior art keywords
didehydro
prodrug forms
dideoxy nucleosides
dideoxy
nucleosides
Prior art date
Application number
NO89891835A
Other languages
English (en)
Norwegian (no)
Other versions
NO891835D0 (no
Inventor
John E Starrett Jr
Muzammil M Mansuri
John C Martin
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NO891835D0 publication Critical patent/NO891835D0/no
Publication of NO891835L publication Critical patent/NO891835L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO89891835A 1988-05-06 1989-05-03 Prodrug-former av 2',3'-didehydro-2',3'-dideoksy-nukleosider. NO891835L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19080988A 1988-05-06 1988-05-06
US33344989A 1989-04-07 1989-04-07

Publications (2)

Publication Number Publication Date
NO891835D0 NO891835D0 (no) 1989-05-03
NO891835L true NO891835L (no) 1989-11-07

Family

ID=26886473

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89891835A NO891835L (no) 1988-05-06 1989-05-03 Prodrug-former av 2',3'-didehydro-2',3'-dideoksy-nukleosider.

Country Status (9)

Country Link
EP (1) EP0340778A3 (fr)
JP (1) JPH02152976A (fr)
KR (1) KR900018093A (fr)
AU (1) AU3407189A (fr)
DK (1) DK221789A (fr)
FI (1) FI892132L (fr)
IL (1) IL90171A0 (fr)
NO (1) NO891835L (fr)
PT (1) PT90475B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0355031A3 (fr) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Nucléosides pyrimidiniques substitués, leur procédé de préparation et médicaments les contenant
DD293498A5 (de) * 1989-07-20 1991-09-05 Zi Fuer Molekularbiologie Der Adw,De Verfahren zur herstellung eines mittels fuer die behandlung oder prophylaxe von hepatits-infektionen bei mensch und tier
WO1991015498A2 (fr) * 1990-04-04 1991-10-17 Nycomed Imaging As Derives nucleosidiques
US5627160A (en) * 1993-05-25 1997-05-06 Yale University L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents
TW374087B (en) * 1993-05-25 1999-11-11 Univ Yale L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents
US5703058A (en) * 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
EP2537839B1 (fr) * 2010-02-15 2016-12-14 Nissan Chemical Industries, Ltd. Composé dérivé de b-dihydrofurane, procédé pour produire un composé dérivé de b-dihydrofurane ou un composé dérivé de b-tétrahydrofurane, composé de b-glycoside, procédé pour produire un composé de b-glycoside, et procédé pour produire le 4'-éthynyl-d4t et des composés analogues de celui-ci
JP5765536B2 (ja) 2010-02-15 2015-08-19 日産化学工業株式会社 β−グリコシド化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960001372B1 (ko) * 1986-09-24 1996-01-26 예일 유니버시티 레트로비루스로 감염된 환자의 치료에 사용되는 2',3'-디디옥시사이티딘-2'-엔(2',3'-디디옥시-2',3'-디디하이드로사이티딘)의 항생물질
US4904770A (en) * 1988-03-24 1990-02-27 Bristol-Myers Company Production of 2',3'-dideoxy-2',3'-didehydronucleosides
EP0355031A3 (fr) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Nucléosides pyrimidiniques substitués, leur procédé de préparation et médicaments les contenant
DE3900964A1 (de) * 1989-01-14 1990-07-19 Boehringer Mannheim Gmbh Neue nukleoside, verfahren zu deren herstellung sowie arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
PT90475A (pt) 1989-11-30
FI892132A7 (fi) 1989-11-07
PT90475B (pt) 1994-08-31
EP0340778A3 (fr) 1990-11-22
IL90171A0 (en) 1989-12-15
DK221789D0 (da) 1989-05-05
DK221789A (da) 1989-11-07
FI892132L (fi) 1989-11-07
NO891835D0 (no) 1989-05-03
KR900018093A (ko) 1990-12-20
AU3407189A (en) 1989-11-09
JPH02152976A (ja) 1990-06-12
EP0340778A2 (fr) 1989-11-08
FI892132A0 (fi) 1989-05-03

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