NO893270L - PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES. - Google Patents

PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES.

Info

Publication number
NO893270L
NO893270L NO89893270A NO893270A NO893270L NO 893270 L NO893270 L NO 893270L NO 89893270 A NO89893270 A NO 89893270A NO 893270 A NO893270 A NO 893270A NO 893270 L NO893270 L NO 893270L
Authority
NO
Norway
Prior art keywords
procedure
preparation
acetic acid
acid derivatives
therapeutic active
Prior art date
Application number
NO89893270A
Other languages
Norwegian (no)
Other versions
NO893270D0 (en
Inventor
Walter Loesel
Otto Roos
Gerd Schnorrenberg
Dietrich Arndts
Georg Speck
Ilse Streller
Werner Traunecker
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO893270D0 publication Critical patent/NO893270D0/en
Publication of NO893270L publication Critical patent/NO893270L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO89893270A 1988-08-16 1989-08-15 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES. NO893270L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3827727A DE3827727A1 (en) 1988-08-16 1988-08-16 ANALYZED TETRAHYDROPYRIDINE IGNESE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE OF SUCH CONNECTIONS FOR CARDIRO PROTECTION

Publications (2)

Publication Number Publication Date
NO893270D0 NO893270D0 (en) 1989-08-15
NO893270L true NO893270L (en) 1990-02-19

Family

ID=6360928

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89893270A NO893270L (en) 1988-08-16 1989-08-15 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES.

Country Status (16)

Country Link
EP (1) EP0358957A1 (en)
JP (1) JPH02160767A (en)
KR (1) KR900003129A (en)
AU (1) AU637767B2 (en)
DD (3) DD285595A5 (en)
DE (1) DE3827727A1 (en)
DK (1) DK399789A (en)
FI (1) FI893832A7 (en)
HU (1) HU208434B (en)
IL (1) IL91301A0 (en)
NO (1) NO893270L (en)
PH (1) PH27356A (en)
PL (1) PL161521B1 (en)
PT (1) PT91451A (en)
YU (1) YU160189A (en)
ZA (1) ZA896205B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162336A (en) * 1990-06-21 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Tetrahydro-pyrido-indoles as cholecystokinin and gastrin antagonists
DE9017900U1 (en) * 1990-12-22 1993-01-28 Boehringer Ingelheim Kg, 55218 Ingelheim 3,4-Dihydro-1-benzyl-6,7-dimethoxy-α-[di-2-(2,3,4-trimethoxyphenyl)ethyl] aminocarbonyl-isoquinoline
DE4104257A1 (en) * 1991-02-13 1992-08-20 Boehringer Ingelheim Kg USE OF ANALYZED TETRAHYDROPYRIDINE IGNESE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL ILLNESSES
US5643919A (en) * 1992-06-22 1997-07-01 Boehringer Ingelheim Kg Anellated dihydropyridines and the use thereof for the production of pharmaceutical preparation
RU2127736C1 (en) * 1992-06-22 1999-03-20 Берингер Ингельгейм КГ Annealed dihydropyridine derivatives or salts thereof with physiologically tolerable acids and agent blocking nonselective cationic passages
EP0957092A1 (en) * 1992-06-22 1999-11-17 Boehringer Ingelheim Pharma KG Ring-closed dihydropyridines and their use in the preparation of pharmaceutical compositions
EP0620222A3 (en) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-beta-carbolines.
ES2152379T3 (en) * 1993-12-21 2001-02-01 Boehringer Ingelheim Pharma CONDENSED DIHYDROPIRIDINS AND ITS USE FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS.
DE4343641A1 (en) * 1993-12-21 1995-06-29 Boehringer Ingelheim Kg Anellated dihydropyridines and their use for the preparation of pharmaceutical preparations
DE4343683A1 (en) * 1993-12-21 1995-06-22 Boehringer Ingelheim Kg Anellated dihydropyridines and their use for the preparation of pharmaceutical preparations
WO2000051998A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
JP2005518378A (en) * 2001-12-19 2005-06-23 ハー・ルンドベック・アクチエゼルスカベット 3,4-Dihydro-IH-isoquinolin-2-yl derivatives
GB2422828A (en) * 2005-02-03 2006-08-09 Hunter Fleming Ltd Tricyclic cytoprotective compounds comprising an indole residue
PT3252057T (en) 2009-12-04 2024-06-04 Sunovion Pharmaceuticals Inc Multicyclic compounds and methods of use thereof
MX2019000982A (en) 2016-07-29 2019-07-04 Sunovion Pharmaceuticals Inc COMPOUNDS AND COMPOSITIONS AND USES THEREOF.
EA201990400A1 (en) 2016-07-29 2019-07-31 Суновион Фармасьютикалз, Инк. COMPOUNDS AND COMPOSITIONS AND THEIR APPLICATION
CN116808023A (en) 2017-02-16 2023-09-29 桑诺维恩药品公司 Method for treating schizophrenia
JP7191085B2 (en) 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク Isochroman compounds and uses thereof
MX2020008537A (en) 2018-02-16 2021-01-08 Sunovion Pharmaceuticals Inc SALTS, CRYSTALLINE FORMS AND METHODS OF PRODUCTION THEREOF.
CN113784755B (en) 2019-03-14 2024-05-10 赛诺维信制药公司 Salts of isochroman-based compounds, crystalline forms thereof, methods of preparation, therapeutic uses and pharmaceutical compositions
CA3180115A1 (en) 2020-04-14 2021-10-21 Sunovion Pharmaceuticals Inc. (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
DE2361390A1 (en) * 1973-12-10 1975-06-19 Merck Patent Gmbh ISOCHINOLINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION
HU174697B (en) * 1976-12-30 1980-03-28 Chinoin Gyogyszer Es Vegyeszet SPOSOB POLUCHENIA NOVYKH PROIZVODNYKH 6,7-DIMETOXY-1,2,3,4-TETRAGIDRO-1-ISOCINOLIN-ACETAMIDA
FR2447921A1 (en) * 1979-02-05 1980-08-29 Synthelabo IMIDAZO AND PYRIMIDO-PYRIDO-INDOLES AND THEIR APPLICATION IN THERAPEUTICS
FR2455044A1 (en) * 1979-04-26 1980-11-21 Synthelabo PYRIDO-INDOLES AND THEIR APPLICATION IN THERAPEUTICS
DE3013906A1 (en) * 1980-04-11 1981-10-15 C.H. Boehringer Sohn, 6507 Ingelheim SUBSTITUTED (ALPHA) -AMINOCARBONYL-L-BENZYL-3,4-DIHYDRO-ISOCHINOLINE, METHOD FOR THE PRODUCTION AND USE THEREOF
DE3229215A1 (en) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1- (HALOGENALKYL) -1,2,3,4-TETRAHYDRO-SS-CARBOLINE, THEIR PRODUCTION AND USE
DE3309596A1 (en) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-SUBSTITUTED 1- (3'-AMINOALKYL) -1,2,3,4-TETRAHYDRO-SS-CARBOLINE, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCT
DE3621413A1 (en) * 1986-06-26 1988-01-07 Boehringer Ingelheim Kg USE OF CARBOCYCLIC AND HETEROCYCLICALLY FURNISHED DIHYDROPYRIDINE AS A CARDIOPROTECTIVE AGENT AND NEW HETEROCYCLIC AND CARBOCYCLICALLY FURNISHED DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND ITS ADDITIONAL PRODUCTS
IL86131A0 (en) * 1987-04-24 1988-11-15 Boehringer Ingelheim Kg Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO893270D0 (en) 1989-08-15
DK399789A (en) 1990-02-17
DK399789D0 (en) 1989-08-15
FI893832A0 (en) 1989-08-15
JPH02160767A (en) 1990-06-20
PT91451A (en) 1990-03-08
HUT51277A (en) 1990-04-28
YU160189A (en) 1992-09-07
DD285595A5 (en) 1990-12-19
PL161521B1 (en) 1993-07-30
PH27356A (en) 1993-06-22
FI893832A7 (en) 1990-02-17
AU637767B2 (en) 1993-06-10
DE3827727A1 (en) 1990-02-22
HU208434B (en) 1993-10-28
AU3992589A (en) 1990-02-22
IL91301A0 (en) 1990-03-19
ZA896205B (en) 1991-04-24
KR900003129A (en) 1990-03-23
EP0358957A1 (en) 1990-03-21
DD295379A5 (en) 1991-10-31
DD297640A5 (en) 1992-01-16

Similar Documents

Publication Publication Date Title
NO894630D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE KINUCLIDINE DERIVATIVES.
NO883974L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDRO-HYDROXYPYRANON DERIVATIVES.
NO864425D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE HETEROCYCLYLOX OTHALAZINYL ACETIC ACID DERIVATIVES.
NO882732D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AMINO ACID DERIVATIVES.
NO871266L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHINAZOLINE DERIVATIVES.
NO904694D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE IMIDAZOLD DERIVATIVES.
NO901684D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 3-SUBSTITUTED-2-OXINDOL DERIVATIVES.
NO893270D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES.
NO870526D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DICHLORANILIN DERIVATIVES.
NO874032D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CATECHOLD DERIVATIVES.
NO156785B (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CYCLOBUTAN DERIVATIVES.
NO883122L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARYLAMIDE DERIVATIVES.
NO875488L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ALKANSULPHONANILIDE DERIVATIVES.
NO891723D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CHINAZOLINE DERIVATIVES.
NO891114L (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ARAKIDONIC ACID DERIVATIVES.
NO881884L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PYRROLIDINE DERIVATIVES.
NO172491C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1,3-DIOXANE-ALCOHIC ACID DERIVATIVES
NO900972D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE NAFTALEN DERIVATIVES.
NO871907D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ALKENAMIDE DERIVATIVES.
NO168825C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 3-PYRROLIDINYLTIO-1-AZABICYCLO (3.2.0) HEPT-2-EN-2 CARBOXYLIC ACID DERIVATIVES
NO900942D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AZACYCLOOKTADIEN DERIVATIVES.
NO890724D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAAZAACENAPYLENE DERIVATIVES.
NO890519D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PROPANON DERIVATIVES.
NO863005D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1,4,5,6,7,8-HEXSAHYDRO-2-ALKYL-4-ARYL-5-OXO-1,7-NAFTYRIDINE-3-CARBOXYL ACID ESTER DERIVATIVES.
NO162239C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BETA-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES.