NO903597L - PHYSIOLOGICALLY COMPATIBLE AMID COMPLEX COMPOUNDS AND THEIR USE IN MANUFACTURING AGENT SPECIFIC ORGANIC SPECIFIC NMR DIAGNOSTICS. - Google Patents

PHYSIOLOGICALLY COMPATIBLE AMID COMPLEX COMPOUNDS AND THEIR USE IN MANUFACTURING AGENT SPECIFIC ORGANIC SPECIFIC NMR DIAGNOSTICS.

Info

Publication number
NO903597L
NO903597L NO90903597A NO903597A NO903597L NO 903597 L NO903597 L NO 903597L NO 90903597 A NO90903597 A NO 90903597A NO 903597 A NO903597 A NO 903597A NO 903597 L NO903597 L NO 903597L
Authority
NO
Norway
Prior art keywords
amid
physiologically compatible
complex compounds
specific
manufacturing agent
Prior art date
Application number
NO90903597A
Other languages
Norwegian (no)
Other versions
NO903597D0 (en
Inventor
Bernd Raduechel
Heribert Schmitt-Willich
Heinz Gries
Gabriele Schuhmann-Giampieri
Hubert Vogler
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO903597D0 publication Critical patent/NO903597D0/en
Publication of NO903597L publication Critical patent/NO903597L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO90903597A 1989-08-16 1990-08-15 PHYSIOLOGICALLY COMPATIBLE AMID COMPLEX COMPOUNDS AND THEIR USE IN MANUFACTURING AGENT SPECIFIC ORGANIC SPECIFIC NMR DIAGNOSTICS. NO903597L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927444A DE3927444A1 (en) 1989-08-16 1989-08-16 USE OF AMID COMPLEX COMPOUNDS

Publications (2)

Publication Number Publication Date
NO903597D0 NO903597D0 (en) 1990-08-15
NO903597L true NO903597L (en) 1991-02-18

Family

ID=6387458

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90903597A NO903597L (en) 1989-08-16 1990-08-15 PHYSIOLOGICALLY COMPATIBLE AMID COMPLEX COMPOUNDS AND THEIR USE IN MANUFACTURING AGENT SPECIFIC ORGANIC SPECIFIC NMR DIAGNOSTICS.

Country Status (10)

Country Link
EP (1) EP0413405A3 (en)
JP (1) JPH03173856A (en)
AU (1) AU6107390A (en)
DE (1) DE3927444A1 (en)
FI (1) FI904060A7 (en)
IE (1) IE902964A1 (en)
IL (1) IL95394A0 (en)
NO (1) NO903597L (en)
PT (1) PT95008A (en)
ZA (1) ZA906511B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077037A (en) * 1990-08-03 1991-12-31 Mallinckrodt Medical, Inc. Novel compositions for magnetic resonance imaging
GB9024208D0 (en) * 1990-11-07 1990-12-19 Salutar Inc Compounds
GB9027922D0 (en) * 1990-12-21 1991-02-13 Nycomed As Compounds
US5463030A (en) * 1991-05-03 1995-10-31 Research Foundation Of The State Of New York Metal chelating agents for medical application
JPH06507904A (en) * 1991-05-23 1994-09-08 イマアーレクス・フアーマシユーチカル・コーポレーシヨン Oil-soluble compounds for magnetic resonance imaging
US6875864B2 (en) 1991-08-01 2005-04-05 Bracco International B.V. Aminocarboxylate ligands having substituted aromatic amide moieties
US5562894A (en) * 1991-08-09 1996-10-08 Regents Of The University Of California Amino-acyl-type and catecholamine-type contrast agents for MRI
WO1993003351A1 (en) * 1991-08-09 1993-02-18 The Regents Of The University Of California Amino acid, ester and/or catechol contrast agents for mri
GB9208908D0 (en) * 1992-04-24 1992-06-10 Nycomed As Contrast agents
DK0603403T4 (en) * 1992-07-03 2002-12-16 Welfide Corp New chelating agent, complex link between this agent and a metal atom and diagnostic agent containing this compound
DE4317588C2 (en) * 1993-05-24 1998-04-16 Schering Ag Macrocyclic metal complexes containing fluorine, process for their preparation and their use
DE4318369C1 (en) * 1993-05-28 1995-02-09 Schering Ag Use of macrocyclic metal complexes as temperature probes
WO1995015319A1 (en) * 1993-12-03 1995-06-08 Bracco S.P.A. Paramagnetic chelates for nuclear magnetic resonance diagnosis
JP3878208B2 (en) * 1994-04-08 2007-02-07 ブラッコ インターナショナル ベスローテン フェンノートシャップ Aromatic amide compounds and their chelates
DE19507822B4 (en) * 1995-02-21 2006-07-20 Schering Ag Substituted DTPA monoamides of the central carboxylic acid and its metal complexes, pharmaceutical compositions containing these complexes, their use in diagnostics and therapy, and methods for the preparation of the complexes and agents
DE19507819A1 (en) * 1995-02-21 1996-08-22 Schering Ag New di:ethylene-tri:amine penta:acetic acid amide complexes
IL117200A0 (en) * 1995-02-21 1996-06-18 Schering Ag Diethylenetriamine-pentaacetic acid monoamide derivatives pharmaceutical compostions containing the same and processes for the preparation thereof
DE19507820A1 (en) * 1995-02-21 1996-08-22 Schering Ag Novel substituted DTPA derivatives, their metal complexes, pharmaceutical compositions containing these complexes, their use in diagnostics, and methods for producing the complexes and compositions
DE19646762B4 (en) * 1996-11-04 2004-05-13 Schering Ag Use of metal compounds for the production of agents for radiotherapy of tumors
JP5406459B2 (en) * 2008-02-20 2014-02-05 光司 山下 Gadolinium compound and contrast medium for MRI

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474533A (en) * 1966-12-14 1969-06-30 Geigy Ag J R Process for the preparation of bis-carboxylic acid anhydrides
DE3129906C3 (en) * 1981-07-24 1996-12-19 Schering Ag Paramagnetic complex salts, their preparation and agents for use in NMR diagnostics
NL194579C (en) * 1983-01-21 2002-08-05 Schering Ag Diagnostic.
US4687659A (en) * 1984-11-13 1987-08-18 Salutar, Inc. Diamide-DTPA-paramagnetic contrast agents for MR imaging
IL83966A (en) * 1986-09-26 1992-03-29 Schering Ag Amides of aminopolycarboxylic acids and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU6107390A (en) 1991-02-21
IE902964A1 (en) 1991-02-27
ZA906511B (en) 1991-09-25
NO903597D0 (en) 1990-08-15
JPH03173856A (en) 1991-07-29
DE3927444A1 (en) 1991-02-28
EP0413405A2 (en) 1991-02-20
FI904060A0 (en) 1990-08-16
PT95008A (en) 1991-04-18
EP0413405A3 (en) 1991-10-16
FI904060A7 (en) 1991-02-17
IL95394A0 (en) 1991-06-30

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