NO913158L - 6-substituert-heksahydrobenz(cd)indoler og fremgangsmaate for deres fremstilling. - Google Patents

6-substituert-heksahydrobenz(cd)indoler og fremgangsmaate for deres fremstilling.

Info

Publication number: NO913158L
Authority: NO; Norway
Prior art keywords: hydrobenz; indoles; procedures; preparation; hex
Prior art date: 1990-08-15

Application number

NO91913158A

Other languages

English (en)

Other versions

NO176019B (no

NO176019C (no

NO913158D0 (no

Inventor

Michael Edward Flaugh

Michael John Martinelli

John Mehnert Schaus

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-15

Filing date

1991-08-13

Publication date

1992-02-17

1991-08-13 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1991-08-13 Publication of NO913158D0 publication Critical patent/NO913158D0/no

1992-02-17 Publication of NO913158L publication Critical patent/NO913158L/no

1994-10-10 Publication of NO176019B publication Critical patent/NO176019B/no

1995-01-18 Publication of NO176019C publication Critical patent/NO176019C/no

Links

150000002475 indoles Chemical class 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Otolaryngology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO913158A 1990-08-15 1991-08-13 Analogifremgangsmåte for fremstilling av terapeutisk aktive 6-substituert-heksahydrobenz(cd)indoler samt mellomprodukter for disse NO176019C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US56798790A	1990-08-15	1990-08-15
US07/725,177 US5229410A (en)	1990-08-15	1991-07-03	6-substituted-hexahydrobenz[cd]indoles

Publications (4)

Publication Number	Publication Date
NO913158D0 NO913158D0 (no)	1991-08-13
NO913158L true NO913158L (no)	1992-02-17
NO176019B NO176019B (no)	1994-10-10
NO176019C NO176019C (no)	1995-01-18

Family

ID=27074631

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO913158A NO176019C (no)	1990-08-15	1991-08-13	Analogifremgangsmåte for fremstilling av terapeutisk aktive 6-substituert-heksahydrobenz(cd)indoler samt mellomprodukter for disse

Country Status (17)

Country	Link
US (1)	US5229410A (no)
EP (1)	EP0471569A1 (no)
JP (1)	JPH04230664A (no)
KR (1)	KR920004346A (no)
CN (1)	CN1058962A (no)
AU (1)	AU648331B2 (no)
BR (1)	BR9103479A (no)
CS (1)	CS249591A3 (no)
FI (1)	FI913834L (no)
HU (1)	HUT59095A (no)
IE (1)	IE912879A1 (no)
IL (1)	IL99149A0 (no)
MX (1)	MX9100644A (no)
NO (1)	NO176019C (no)
NZ (1)	NZ239334A (no)
PT (1)	PT98639A (no)
YU (1)	YU140391A (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5204340A (en) *	1989-04-11	1993-04-20	Eli Lilly And Company	Tetrahydrobenz(c,d)indole serotonin agonists
EP0471515B1 (en) *	1990-08-15	1997-03-05	Eli Lilly And Company	Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes
US5364856A (en) *	1991-03-28	1994-11-15	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5643934A (en) *	1991-03-28	1997-07-01	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz [CD]indoles
US5347013A (en) *	1991-03-28	1994-09-13	Eli Lilly And Company	6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5292766A (en) *	1992-03-25	1994-03-08	Eli Lilly And Company	Method for improving primary memory and/or learning
US5385928A (en) *	1994-05-18	1995-01-31	Eli Lilly And Company	Tetrahydrobenz [CD] indazoles, compositions and use
WO1998046353A1 (en)	1997-04-15	1998-10-22	Massachusetts Institute Of Technology	Synthesis and application of vapor grafted porous materials
KR20050043568A (ko) *	2003-11-06	2005-05-11	김상현	두족류 연체동물 포획용 분할형 인공패각

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE517732C (de) *	1927-10-27	1931-02-09	Then Rudolf	Faerbekufe mit einem drehbaren, trommelartigen Rahmen fuer die auf aus-wechselbaren Faerbestoecken aufgehaengten Waren, insbesondere Struempfe
BE542760A (no) *	1954-11-12
US3194811A (en) *	1963-09-05	1965-07-13	Merck & Co Inc	Aroyl-benzindolyl acids
BE755270A (fr) *	1969-08-27	1971-02-25	Sandoz Sa	Nouveaux derives du benzo(cd)indole, leur preparation et medicaments contenant ces derives
FI206974A7 (no) *	1973-07-16	1975-01-17	Sandoz Ag
US4110339A (en) *	1977-11-25	1978-08-29	Eli Lilly And Company	4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
FR2522658A1 (fr) *	1982-03-05	1983-09-09	Roussel Uclaf	Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation
DE3346573A1 (de) *	1983-12-23	1985-07-04	Troponwerke GmbH & Co KG, 5000 Köln	1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
US4576959A (en) *	1984-02-06	1986-03-18	Eli Lilly And Company	6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4983622A (en) *	1984-02-06	1991-01-08	Eli Lilly And Company	6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
IL74222A (en) *	1984-02-06	1988-07-31	Lilly Co Eli	6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
CA1266482A1 (en) *	1984-05-24	1990-03-06	Carl Kaiser	6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
DE3525564A1 (de) *	1985-07-15	1987-02-05	Schering Ag	Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
US4745126A (en) *	1987-03-12	1988-05-17	Eli Lilly And Company	Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3718892A1 (de) *	1987-06-05	1988-12-22	Bayer Ag	Polyhydrobenz(c,d)indol-sulfonamide
IL97308A (en) *	1990-02-26	1996-10-31	Lilly Co Eli	6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
US5039820A (en) *	1990-02-26	1991-08-13	Eli Lilly And Company	4-amino-6-iodo-hexahydrobenz(cd)indoles
US5096908A (en) *	1990-05-04	1992-03-17	Eli Lilly And Company	Method of inhibiting gastric acid secretion
US5229409A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-tetrahydrobenz[cd]indoles
ZA917355B (en) *	1990-09-17	1992-08-26	Agouron Pharma	Antiproliferative substituted naphthalene compounds

1991
- 1991-07-03 US US07/725,177 patent/US5229410A/en not_active Expired - Fee Related
- 1991-08-09 IL IL99149A patent/IL99149A0/xx unknown
- 1991-08-09 NZ NZ239334A patent/NZ239334A/xx unknown
- 1991-08-12 CS CS912495A patent/CS249591A3/cs unknown
- 1991-08-12 PT PT98639A patent/PT98639A/pt not_active Application Discontinuation
- 1991-08-13 FI FI913834A patent/FI913834L/fi not_active Application Discontinuation
- 1991-08-13 AU AU82407/91A patent/AU648331B2/en not_active Ceased
- 1991-08-13 NO NO913158A patent/NO176019C/no unknown
- 1991-08-13 KR KR1019910013966A patent/KR920004346A/ko not_active Withdrawn
- 1991-08-13 MX MX9100644A patent/MX9100644A/es unknown
- 1991-08-14 CN CN91105627A patent/CN1058962A/zh active Pending
- 1991-08-14 JP JP3204238A patent/JPH04230664A/ja not_active Withdrawn
- 1991-08-14 IE IE287991A patent/IE912879A1/en unknown
- 1991-08-14 EP EP91307509A patent/EP0471569A1/en not_active Withdrawn
- 1991-08-14 BR BR919103479A patent/BR9103479A/pt not_active Application Discontinuation
- 1991-08-14 YU YU140391A patent/YU140391A/sh unknown
- 1991-08-14 HU HU912707A patent/HUT59095A/hu unknown

Also Published As

Publication number	Publication date
PT98639A (pt)	1992-06-30
NO176019B (no)	1994-10-10
HUT59095A (en)	1992-04-28
BR9103479A (pt)	1992-05-12
AU8240791A (en)	1992-02-20
NO176019C (no)	1995-01-18
FI913834A0 (fi)	1991-08-13
FI913834A7 (fi)	1992-02-16
US5229410A (en)	1993-07-20
NO913158D0 (no)	1991-08-13
CN1058962A (zh)	1992-02-26
FI913834L (fi)	1992-02-16
HU912707D0 (en)	1992-01-28
JPH04230664A (ja)	1992-08-19
IE912879A1 (en)	1992-02-26
EP0471569A1 (en)	1992-02-19
NZ239334A (en)	1993-05-26
CS249591A3 (en)	1992-03-18
KR920004346A (ko)	1992-03-27
MX9100644A (es)	1992-04-01
AU648331B2 (en)	1994-04-21
YU140391A (sh)	1994-06-10
IL99149A0 (en)	1992-07-15

Publication	Publication Date	Title
NO882390D0 (no)	1988-05-31	(ih-azol-1-ylmetyl)substituerte benzotriazolderivater og deres fremstilling.
DK297089A (da)	1989-12-17	Pyrimidinderivater og fremgangsmaade til fremstilling deraf
DK48785A (da)	1985-09-03	6-substituerede 4-dialkylaminotetrahydrobenz(c,d)indoler og fremgangsmaade til fremstilling heraf
NO891866D0 (no)	1989-05-05	Kromanderivater og fremgangsmaate for fremstilling derav.
NO904921L (no)	1991-05-15	Fremgangsmaate til fremstilling av modifiserte gangliosider og deres funksjonelle derivater.
NO904551D0 (no)	1990-10-22	Quinolonforbindelser og fremgangsmaate for deres fremstilling.
NO910003D0 (no)	1991-01-02	Vitamin e derivater og fremgangsmaate for deres fremstilling.
NO870512D0 (no)	1987-02-10	1,4-benzoksazinderivater og fremgangsmaate for deres fremstilling.
NO893196D0 (no)	1989-08-08	Hybrid-protein-c-sammensetninger og fremgangsmaater for deres fremstilling.
DK581688A (da)	1989-04-20	L-tyrosinderivater og fremgangsmaade til fremstilling af samme
NO890894D0 (no)	1989-03-02	4-substituerte pyrazolo(3,4-alfa)pyrimidinderivater og fremgangsmaate for deres fremstilling.
NO892494D0 (no)	1989-06-15	Kromanderivater og fremgangsmaate for fremstilling derav.
NO913158D0 (no)	1991-08-13	6-substituert-heksahydrobenz(cd)indoler og fremgangsmaate for deres fremstilling.
NO880511D0 (no)	1988-02-05	Substituerte aminderivater og fremgangsmaater for deres fremstilling.
NO904552L (no)	1991-04-24	Quinolonforbindelser og fremgangsmaate for deres fremstilling.
NO894103L (no)	1990-04-17	Kromanderivater og fremgangsmaate for fremstilling derav.
NO911047D0 (no)	1991-03-15	Labdaner og fremgangsmaate for deres fremstilling.
NO883114D0 (no)	1988-07-12	1h-pyrazol-1-alkanamider og fremgangsmaate for deres fremstilling.
NO904805D0 (no)	1990-11-05	Fremgangsmaate for fremstilling av antihypertensive og antiarytmiske pyridinderivater.
NO893653D0 (no)	1989-09-12	Quinolinderivater og deres fremstilling.
NO903484D0 (no)	1990-08-08	Substituerte pyrazinderivater og fremgangsmaate for deres fremstilling.
NO900252D0 (no)	1990-01-18	Cefasporinderivater og fremgangsmaate for fremstilling derav.
NO893565L (no)	1990-03-07	Etansulfonamidderivater og fremgangsmaate for deres fremstilling.
NO894697L (no)	1990-05-28	Penemderivater og fremgangsmaater for deres fremstilling.
NO872885L (no)	1988-01-18	1,3,5-tritianderivater og fremgangsmte for deres fremstilling.