NO921191L - Dibenzofurankarboksamider - Google Patents

Dibenzofurankarboksamider

Info

Publication number
NO921191L
NO921191L NO92921191A NO921191A NO921191L NO 921191 L NO921191 L NO 921191L NO 92921191 A NO92921191 A NO 92921191A NO 921191 A NO921191 A NO 921191A NO 921191 L NO921191 L NO 921191L
Authority
NO
Norway
Prior art keywords
dibenzofurankarboksamider
antiemetic
dibenzofuran
carboxamides
antagonists
Prior art date
Application number
NO92921191A
Other languages
English (en)
Other versions
NO921191D0 (no
Inventor
Raymond D Youssefyeh
Henry F Campbell
Donald E Kuhla
John Edward Airey
Scott Ira Klein
Matthew Ray Powers
Original Assignee
Rhone Poulenc Rorer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Int filed Critical Rhone Poulenc Rorer Int
Publication of NO921191L publication Critical patent/NO921191L/no
Publication of NO921191D0 publication Critical patent/NO921191D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Denne oppfinnelse er rettet mot visse dibenzofurankarboksamider og deres anvendelse som 5HT-antagonister med unik CNS-, antiemetisk og gastrisk prokinetisk aktivitet frie for enhver signifikant D-reseptorbindingsegen-skap. Denne oppfinnelse beskriver også nye fremgangsmåter nødvendig for deres fremstilling.
NO1992921191A 1989-09-27 1992-03-26 Dibenzofurankarboksamider NO921191D0 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/004221 WO1991004738A1 (en) 1989-09-27 1989-09-27 Dibenzofurancarboxamides

Publications (2)

Publication Number Publication Date
NO921191L true NO921191L (no) 1992-03-26
NO921191D0 NO921191D0 (no) 1992-03-26

Family

ID=22215253

Family Applications (1)

Application Number Title Priority Date Filing Date
NO1992921191A NO921191D0 (no) 1989-09-27 1992-03-26 Dibenzofurankarboksamider

Country Status (5)

Country Link
EP (1) EP0494140A4 (no)
DK (1) DK40292A (no)
FI (1) FI921332A0 (no)
NO (1) NO921191D0 (no)
WO (1) WO1991004738A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710274A (en) * 1996-02-28 1998-01-20 Neurogen Corporation N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subtype specific ligands
CN116535379B (zh) * 2023-06-29 2023-09-19 希格生科（深圳）有限公司 化合物及其医药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
ZA832549B (en) * 1982-04-14 1988-09-28 Beecham Group Plc Pharmaceutically active compounds
US4863921A (en) * 1988-04-27 1989-09-05 Rorer Pharmaceutical Corporation Dibenzofurancarboxamides and their pharmaceutical compositions and methods

Also Published As

Publication number Publication date
WO1991004738A1 (en) 1991-04-18
EP0494140A1 (en) 1992-07-15
EP0494140A4 (en) 1992-09-02
NO921191D0 (no) 1992-03-26
DK40292D0 (da) 1992-03-26
DK40292A (da) 1992-05-26
FI921332L (fi) 1992-03-26
FI921332A7 (fi) 1992-03-26
FI921332A0 (fi) 1992-03-26

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