NO922005L - Farmasoeytiske preparater - Google Patents

Farmasoeytiske preparater

Info

Publication number
NO922005L
NO922005L NO92922005A NO922005A NO922005L NO 922005 L NO922005 L NO 922005L NO 92922005 A NO92922005 A NO 92922005A NO 922005 A NO922005 A NO 922005A NO 922005 L NO922005 L NO 922005L
Authority
NO
Norway
Prior art keywords
polyethylene glycol
capsule
dissolved
filler
weight
Prior art date
Application number
NO92922005A
Other languages
English (en)
Other versions
NO922005D0 (no
Inventor
Alfred Paul Launchbury
Frank Samuel Short Morton
Dennis Rowe
Original Assignee
Erba Farmitalia
Scherer Ltd R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia, Scherer Ltd R P filed Critical Erba Farmitalia
Publication of NO922005L publication Critical patent/NO922005L/no
Publication of NO922005D0 publication Critical patent/NO922005D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

En farmasøytisk enhetsdoseform omfattende et myk- gelatlnkapselskall eller en todelt hårdgelatlnkapsel og et fyllstoff omfattende et benzodiazepin, opplest eller suspendert i en gel, der gelen har et dryppepunkt (C) før innkapsling på minst 46 og består av minst 63 % polyetylenglykol 600, minst 4 vekt-* polyetylenglykol 4000 eller 6000 og minst 21 vekt-56 av en mellomliggende polyetylenglykol. Gel-fyllmaterlalet som benyttes ifølge oppfinnelsen kan ikke presses ut fra noen sprøyte ved omgivelsestempera- tur og fjerner derfor tilgjengeligheten for intravenøs- medikament-misbrukere av en kapsel inneholdende et medikament, oppløst eller dlspergert i et flytende fyllstoff. Kapselfyllet bibeholder god biotilgjengelig- het og farmakoklnetiske egenskaper.
NO922005A 1989-11-24 1992-05-21 Farmasoeytiske preparater NO922005D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898926612A GB8926612D0 (en) 1989-11-24 1989-11-24 Pharmaceutical compositions
PCT/GB1990/001821 WO1991007950A1 (en) 1989-11-24 1990-11-23 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
NO922005L true NO922005L (no) 1992-05-21
NO922005D0 NO922005D0 (no) 1992-05-21

Family

ID=10666868

Family Applications (1)

Application Number Title Priority Date Filing Date
NO922005A NO922005D0 (no) 1989-11-24 1992-05-21 Farmasoeytiske preparater

Country Status (10)

Country Link
EP (1) EP0502042B1 (no)
AU (1) AU652924B2 (no)
DE (1) DE69018647T2 (no)
DK (1) DK0502042T3 (no)
FI (1) FI922364L (no)
GB (2) GB8926612D0 (no)
NO (1) NO922005D0 (no)
PT (1) PT95991B (no)
WO (1) WO1991007950A1 (no)
ZA (1) ZA909426B (no)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ280610A (en) * 1994-12-29 1997-08-22 Mcneil Ppc Inc Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
US5660859A (en) * 1994-12-29 1997-08-26 Mcneil-Ppc, Inc. Gelling agent for polyethylene glycol
US5919481A (en) * 1996-06-28 1999-07-06 Ncneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form
US6024980A (en) * 1996-06-28 2000-02-15 Mcneil-Ppc, Inc. Multiphase soft gelatin dosage form
US5908636A (en) * 1996-06-28 1999-06-01 Mcneil-Ppc, Inc. Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent
FR2787715B1 (fr) * 1998-12-23 2002-05-10 Synthelabo Composition pharmaceutique comprenant un compose hypnotique ou un de ses sels pharmaceutiquement acceptables
KR20030034171A (ko) 2001-07-06 2003-05-01 엔도 파마슈티걸즈, 인크. 옥시모르폰 제어 방출 제형
DK1404331T3 (da) 2001-07-06 2008-01-28 Penwest Pharmaceuticals Co Sustained release-formuleringer af oxymorphon
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
WO2003013481A1 (en) * 2001-08-03 2003-02-20 Bakulesh Mafatlal Khamar The process of manufacturing pharmaceutical composition with increased content of poorly soluble pharmaceutical ingredients
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20030068276A1 (en) 2001-09-17 2003-04-10 Lyn Hughes Dosage forms
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP2218448B1 (en) * 2002-12-13 2015-09-23 Durect Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
WO2004112756A1 (en) 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
ES2653568T3 (es) 2004-06-12 2018-02-07 Collegium Pharmaceutical, Inc. Formulaciones de fármacos para la prevención del abuso
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
DK2767292T3 (en) 2004-09-17 2016-12-19 Durect Corp RENEWABLE local anesthetic COMPOSITION CONTAINING SAIB
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CN104825397A (zh) 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
AU2007325918B2 (en) 2006-11-03 2013-10-17 Durect Corporation Transdermal delivery systems comprising bupivacaine
EP2067471B1 (en) 2007-12-06 2018-02-14 Durect Corporation Oral pharmaceutical dosage forms
TWI454288B (zh) 2008-01-25 2014-10-01 Gruenenthal Chemie 藥物劑型
ES2599031T3 (es) 2008-05-09 2017-01-31 Grünenthal GmbH Proceso para la preparación de una formulación de polvo intermedia y una forma de dosificación solida final utilizando un paso de congelación por pulverización
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
BR112012001466A2 (pt) 2009-07-22 2020-08-11 Grünenthal GmbH forma de dosagem resistente à falsificação para opioides sensíveis à oxidação, seu processo de fabricação, e embalagem
ES2534908T3 (es) 2009-07-22 2015-04-30 Grünenthal GmbH Forma de dosificación de liberación controlada extruida por fusión en caliente
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
WO2012028318A1 (en) 2010-09-02 2012-03-08 Grünenthal GmbH Tamper resistant dosage form comprising an anionic polymer
CA2808219C (en) 2010-09-02 2019-05-14 Gruenenthal Gmbh Tamper resistant dosage form comprising inorganic salt
PL2826467T3 (pl) 2010-12-22 2018-01-31 Purdue Pharma Lp Zamknięte, zabezpieczone przed manipulowaniem formy dozowania o kontrolowanym uwalnianiu
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
JP6063462B2 (ja) 2011-07-29 2017-01-18 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 即時薬剤放出を提供するタンパーレジスタント錠剤
BR112014002022A2 (pt) 2011-07-29 2017-02-21 Gruenenthal Gmbh comprimido resistente à violação proporcionando liberação de fármaco imediata
BR112014019988A8 (pt) 2012-02-28 2017-07-11 Gruenenthal Gmbh Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico
LT2838512T (lt) 2012-04-18 2018-11-12 GrĆ¼nenthal GmbH Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
PE20151301A1 (es) 2013-02-05 2015-09-16 Purdue Pharma Lp Formulaciones farmaceuticas resistentes a la manipulacion indebida
CA2905131A1 (en) 2013-03-15 2014-09-18 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
US10420729B2 (en) 2013-03-15 2019-09-24 R.P. Scherer Technologies, Llc Abuse resistant capsule
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
AU2014273227B2 (en) 2013-05-29 2019-08-15 Grunenthal Gmbh Tamper-resistant dosage form containing one or more particles
MX2015016254A (es) 2013-05-29 2016-04-20 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
AU2014289187B2 (en) 2013-07-12 2019-07-11 Grunenthal Gmbh Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
HK1224189A1 (zh) 2013-11-26 2017-08-18 Grünenthal GmbH 通过低温研磨制备粉状药物组合物
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015173195A1 (en) 2014-05-12 2015-11-19 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
US9872835B2 (en) 2014-05-26 2018-01-23 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
GB201409471D0 (en) 2014-05-28 2014-07-09 Euro Celtique Sa Pharmaceutical composition
DK3169315T3 (da) 2014-07-17 2020-08-10 Pharmaceutical Manufacturing Res Services In Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
US9908976B2 (en) * 2015-03-18 2018-03-06 Psmg, Llc Stable polyethylene glycol particle dispersions and methods for forming the stable dispersions
WO2016170097A1 (en) 2015-04-24 2016-10-27 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
CA2998259A1 (en) 2015-09-10 2017-03-16 Grunenthal Gmbh Protecting oral overdose with abuse deterrent immediate release formulations
WO2017205939A1 (en) * 2016-06-03 2017-12-07 Indigo Ridge Pty Ltd Vitamin d formulations and therapeutic uses thereof
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
CN109475505A (zh) 2016-07-06 2019-03-15 度瑞公司 具有药物组成物、屏障层及药物层的口服剂型
WO2018068832A1 (en) 2016-10-11 2018-04-19 Euro-Celtique S.A. Hodgkin lymphoma therapy
GB201709403D0 (en) 2017-06-13 2017-07-26 Euro Celtique Sa Compounds for treating sarcoma
EP3897626B1 (en) 2018-12-18 2025-09-10 Mundipharma International Corporation Limited Tinostamustine for treating multiple myeloma
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CA3203561A1 (en) 2021-01-12 2022-07-21 Adrian Neil Verity Sustained release drug delivery systems and related methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2614864C3 (de) * 1976-04-06 1979-11-29 Schwabe, Willmar, Dr., 7500 Karlsruhe Verfahren zur Herstellung Digoxin enthaltender Arzneipräparate in Weichgelatinekapseln zur oralen Verabfolgung
DE3307353C2 (de) * 1983-03-02 1985-01-31 R.P. Scherer GmbH, 6930 Eberbach Polyethylenglykolhaltige Weichgelatinekapsel und Verfahren zu ihrer Herstellung
NL8520012A (nl) * 1984-02-08 1986-01-02 Scherer Corp R P Aceetaminofeen gelatinecapsule, die snelle aanvang van therapeutische activiteit na orale toediening oplevert.
GB2185887B (en) * 1987-02-18 1989-12-06 Farmitalia Carlo Erba Ltd Temazepam composition

Also Published As

Publication number Publication date
PT95991B (pt) 1998-01-30
FI922364A7 (fi) 1992-05-22
AU6746190A (en) 1991-06-26
NO922005D0 (no) 1992-05-21
DE69018647D1 (de) 1995-05-18
AU652924B2 (en) 1994-09-15
EP0502042B1 (en) 1995-04-12
GB9025491D0 (en) 1991-01-09
WO1991007950A1 (en) 1991-06-13
FI922364A0 (fi) 1992-05-22
EP0502042A1 (en) 1992-09-09
ZA909426B (en) 1991-09-25
DE69018647T2 (de) 1995-08-10
GB8926612D0 (en) 1990-01-17
FI922364L (fi) 1992-05-22
GB2238478B (en) 1993-11-17
PT95991A (pt) 1991-09-13
DK0502042T3 (da) 1995-06-26
GB2238478A (en) 1991-06-05

Similar Documents

Publication Publication Date Title
NO840793L (no) Farmasoeytisk middel
HUP9701111A2 (hu) Töltőanyag lágy zselatin kapszula gyógyszeradagolási formához
DE3684354D1 (de) Arzneimittel, die hohle, feine, roehrchenfoermige wirkstoffabgabesysteme enthalten.
KR880009639A (ko) 서방성 매트릭스 제형
ATE84032T1 (de) Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
GEP20032941B (en) Gastroprotected Omerprazole Microgranules, Method for Obtaining Same and Pharmaceutical Preparations
DK647789D0 (da) Kosmetisk eller farmaceutisk komposition indeholdende mikrosfaerer af polymere eller af fedtstofferforsynet med mindst et aktivt produkt
FR2334359A1 (fr) Derives de l'isoquinoleine, leur preparation et medicaments contenant ces substances
NO963202D0 (no) Misbruksresistente tabletter
FR2778406B1 (fr) Derives d'alpha-cetoamides, procede pour leur preparation, preparations pharmaceutiques les contenant, et leur utilisation en tant que medicaments anti-viraux
KR870006893A (ko) 고점성 하이드로겔 또는 그 현탁액의 약학적 제제
RU94043798A (ru) Новая диффузионно-осмотическая фармацевтическая композиция с регулируемым выделением лекарства и способ ее получения
BE860726A (fr) Nouveaux aryl-acylamides n-(2-aminocy-cloaliphatiques), leur procede de preparation et medicament les contenant
KR840003415A (ko) 경구용 당뇨병 치료제의 제조방법
IT1240768B (it) Composizione farmaceutica contenente ranitidina sotto forma di capsule di gelatina.
ATE17725T1 (de) Gegen entzuendung wirksame 5-substituierte 2,3diaryl-thiophene, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
JPS61501202A (ja) アセトアミノフェン・ゼラチンカプセル
KR850700218A (ko) 약학 조성물
ES2016620B3 (es) Sistema para liberar medicamentos con bioaceptabilidad mejorada.
DE3874390D1 (de) Carboxystyrol-derivate und arzneimittel, die sie als wirkstoff enthalten.
ATE85213T1 (de) Einen wirkstoff und ein in wasser quellendes polymer enthaltendes arzneimittel.
AU2503900A (en) Sulfated phosphatidylinositols, their preparation and use
TR199901237T2 (xx) Bir tienilsiklohegzilamin t�revinin tedavide yeni uygulamas�.
SE9402455D0 (sv) Bilayer preparations
ES2127305T3 (es) Una forma farmaceutica para la administracion rectal de compuestos farmacologicamente activos.