NO923049L - Substituerte dibenz(b,f)(1,4)oksazepin-11(10h)-oner, fremgangsmaate til fremstilling derav og preparater inneholdende slike - Google Patents

Substituerte dibenz(b,f)(1,4)oksazepin-11(10h)-oner, fremgangsmaate til fremstilling derav og preparater inneholdende slike

Info

Publication number: NO923049L
Authority: NO; Norway
Prior art keywords: oksazepin; ones; procedures; preparing; preparations containing
Prior art date: 1991-08-26

Application number

NO92923049A

Other languages

English (en)

Other versions

NO923049D0 (no

NO301586B1 (no

Inventor

Ivo Monkovic

Lotte Wang

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-08-26

Filing date

1992-08-03

Publication date

1993-03-01

1992-08-03 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1992-08-03 Publication of NO923049D0 publication Critical patent/NO923049D0/no

1993-03-01 Publication of NO923049L publication Critical patent/NO923049L/no

1997-11-17 Publication of NO301586B1 publication Critical patent/NO301586B1/no

Links

238000000034 method Methods 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000003560 cancer drug Substances 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
230000036457 multidrug resistance Effects 0.000 abstract 1
150000003254 radicals Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/04—Seven-membered rings having the hetero atoms in positions 1 and 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Photoreceptors In Electrophotography (AREA)

NO923049A 1991-08-26 1992-08-03 Dibenz£b,f|£1,4|oksazepin-11(10H)oner, fremgangsmåte til fremstilling derav og farmasöytisk preparat inneholdende dem NO301586B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/749,741 US5173486A (en)	1991-08-26	1991-08-26	Dibenz[b,f][1,4]oxazepin-11(10H)-ones for multidrug resistance reversing agents

Publications (3)

Publication Number	Publication Date
NO923049D0 NO923049D0 (no)	1992-08-03
NO923049L true NO923049L (no)	1993-03-01
NO301586B1 NO301586B1 (no)	1997-11-17

Family

ID=25014983

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO923049A NO301586B1 (no)	1991-08-26	1992-08-03	Dibenz£b,f\|£1,4\|oksazepin-11(10H)oner, fremgangsmåte til fremstilling derav og farmasöytisk preparat inneholdende dem
NO972247A NO309603B1 (no)	1991-08-26	1997-05-16	Fremgangsmåte til fremstilling av substituerte dibenz[b,f][1,4]-oksazepin-11(10H)oner

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO972247A NO309603B1 (no)	1991-08-26	1997-05-16	Fremgangsmåte til fremstilling av substituerte dibenz[b,f][1,4]-oksazepin-11(10H)oner

Country Status (22)

Country	Link
US (1)	US5173486A (no)
EP (1)	EP0529386B1 (no)
JP (1)	JP3136427B2 (no)
KR (1)	KR100204119B1 (no)
CN (1)	CN1038749C (no)
AT (1)	ATE149158T1 (no)
AU (1)	AU642602B2 (no)
CA (1)	CA2075861C (no)
DE (1)	DE69217594T2 (no)
DK (1)	DK0529386T3 (no)
ES (1)	ES2097841T3 (no)
FI (1)	FI112656B (no)
GR (1)	GR3022698T3 (no)
HK (1)	HK1005029A1 (no)
HU (1)	HU214584B (no)
IL (1)	IL102542A (no)
MX (1)	MX9204791A (no)
NO (2)	NO301586B1 (no)
PL (1)	PL168707B1 (no)
RU (1)	RU2086545C1 (no)
TW (1)	TW213905B (no)
ZA (1)	ZA925287B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8914061D0 (en) *	1989-06-19	1989-08-09	Wellcome Found	Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
US5436243A (en) *	1993-11-17	1995-07-25	Research Triangle Institute Duke University	Aminoanthraquinone derivatives to combat multidrug resistance
US5767113A (en) *	1995-05-10	1998-06-16	The Salk Institute For Biological Studies	Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance
US6407125B1 (en)	1995-12-29	2002-06-18	Novactyl, Inc.	Pharmacological agent and method of treatment
US6579891B1 (en)	1995-12-29	2003-06-17	Novactyl, Inc.	Agent and method for prevention and treatment of cancer in animals
US6743771B2 (en)	1995-12-29	2004-06-01	Novactyl, Inc.	Methods and compositions for controlling protein assembly or aggregation
US6127393A (en)	1995-12-29	2000-10-03	Novactyl, Inc.	Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method
PT101876B (pt) *	1996-05-27	1999-09-30	Portela & Ca Sa	Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
PE69598A1 (es) *	1996-06-07	1998-11-14	Hoffmann La Roche	Derivados de dibenzo-oxazepina y dioxepina
US6441009B1 (en)	1998-08-01	2002-08-27	Novactyl, Inc.	Agent and method of preventing and treating heavy metal exposure and toxicity
SE9803240D0 (sv) *	1998-09-24	1998-09-24	Diabact Ab	A pharmaceutical composition having a rapid action
US6403618B1 (en)	2000-02-15	2002-06-11	Novactyl, Inc.	Agent and method for controlling angiogenesis
US6376514B1 (en)	2000-10-17	2002-04-23	The Procter & Gamble Co.	Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en)	2000-10-17	2004-02-17	The Procter & Gamble Company	Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
RU2266286C1 (ru) *	2004-07-20	2005-12-20	Ярославский государственный технический университет	Гетероциклические о-дикарбонитрилы
PL2149372T3 (pl) *	2008-07-31	2015-03-31	Univ Ulm	Zastosowanie opioidów z grupy metadonu w leczeniu opornych pacjentów onkologicznych
CN104016937B (zh) *	2014-05-09	2016-12-07	中科院广州化学有限公司	一种n-芳基氧氮杂卓酮类化合物及其制备方法
WO2019173761A1 (en)	2018-03-09	2019-09-12	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	C-abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3546214A (en) *	1967-07-11	1970-12-08	Boehringer Sohn Ingelheim	Amino-substituted dibenz(b,f)(1,4)oxazepin-11(10h)-ones

1991
- 1991-08-26 US US07/749,741 patent/US5173486A/en not_active Expired - Lifetime
1992
- 1992-07-15 HU HU9202319A patent/HU214584B/hu not_active IP Right Cessation
- 1992-07-15 ZA ZA925287A patent/ZA925287B/xx unknown
- 1992-07-17 IL IL10254292A patent/IL102542A/en not_active IP Right Cessation
- 1992-07-17 FI FI923285A patent/FI112656B/fi active
- 1992-07-20 TW TW081105730A patent/TW213905B/zh active
- 1992-07-30 JP JP04243972A patent/JP3136427B2/ja not_active Expired - Fee Related
- 1992-08-03 AU AU20742/92A patent/AU642602B2/en not_active Ceased
- 1992-08-03 NO NO923049A patent/NO301586B1/no unknown
- 1992-08-10 DK DK92113590.1T patent/DK0529386T3/da active
- 1992-08-10 AT AT92113590T patent/ATE149158T1/de not_active IP Right Cessation
- 1992-08-10 DE DE69217594T patent/DE69217594T2/de not_active Expired - Fee Related
- 1992-08-10 ES ES92113590T patent/ES2097841T3/es not_active Expired - Lifetime
- 1992-08-10 EP EP92113590A patent/EP0529386B1/en not_active Expired - Lifetime
- 1992-08-12 KR KR1019920014502A patent/KR100204119B1/ko not_active Expired - Fee Related
- 1992-08-12 CA CA002075861A patent/CA2075861C/en not_active Expired - Fee Related
- 1992-08-14 CN CN92109400A patent/CN1038749C/zh not_active Expired - Fee Related
- 1992-08-14 PL PL92295633A patent/PL168707B1/pl not_active IP Right Cessation
- 1992-08-19 MX MX9204791A patent/MX9204791A/es unknown
- 1992-08-25 RU SU925052449A patent/RU2086545C1/ru not_active IP Right Cessation
1997
- 1997-02-27 GR GR970400381T patent/GR3022698T3/el unknown
- 1997-05-16 NO NO972247A patent/NO309603B1/no unknown
1998
- 1998-05-15 HK HK98104207A patent/HK1005029A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL102542A0 (en)	1993-01-14
ATE149158T1 (de)	1997-03-15
RU2086545C1 (ru)	1997-08-10
NO972247D0 (no)	1997-05-16
NO923049D0 (no)	1992-08-03
JPH05194442A (ja)	1993-08-03
CA2075861C (en)	2003-08-05
DE69217594T2 (de)	1997-10-02
ES2097841T3 (es)	1997-04-16
ZA925287B (en)	1993-04-28
PL295633A1 (en)	1993-03-08
FI112656B (fi)	2003-12-31
CN1038749C (zh)	1998-06-17
KR100204119B1 (ko)	1999-06-15
FI923285A0 (fi)	1992-07-17
US5173486A (en)	1992-12-22
HUT63837A (en)	1993-10-28
CA2075861A1 (en)	1993-02-27
EP0529386A1 (en)	1993-03-03
NO972247L (no)	1997-05-16
NO301586B1 (no)	1997-11-17
DK0529386T3 (da)	1997-07-28
HU9202319D0 (en)	1992-10-28
AU2074292A (en)	1993-03-04
GR3022698T3 (en)	1997-05-31
CN1069731A (zh)	1993-03-10
AU642602B2 (en)	1993-10-21
HK1005029A1 (en)	1998-12-18
HU214584B (hu)	1998-04-28
EP0529386B1 (en)	1997-02-26
MX9204791A (es)	1993-01-01
FI923285L (fi)	1993-02-27
PL168707B1 (pl)	1996-03-29
KR930004281A (ko)	1993-03-22
DE69217594D1 (de)	1997-04-03
JP3136427B2 (ja)	2001-02-19
IL102542A (en)	1995-12-31
TW213905B (no)	1993-10-01
NO309603B1 (no)	2001-02-26

Publication	Publication Date	Title
NO923049D0 (no)	1992-08-03	Substituerte dibenz(b,f)(1,4)oksazepin-11(10h)-oner, fremgangsmaate til fremstilling derav og preparater inneholdende slike
MY129970A (en)	2007-05-31	Hypolipidaemic compounds
NO923679L (no)	1993-03-24	Nye substituerte taksaner og farmasoeytiske preparater sominneholder slike
NO930881L (no)	1993-09-13	Anti-tumor forbindelser
DE69101802D1 (de)	1994-06-01	Antihypercholesterolemika.
ATE181066T1 (de)	1999-06-15	Zwischenverbindungen zur herstellung von thioalkylthio cephalosporinderivaten
DE3681109D1 (de)	1991-10-02	Stickstoffhaltige heterozyklische verbindungen.
DE69524154D1 (de)	2002-01-10	7-O-Ether von Taxanderivaten
DK0382660T3 (da)	1993-06-01	Dioxaphosphorinanforbindelser og dermed stabiliserede polyolefinmaterialer
FI882358A0 (fi)	1988-05-19	Cykliska antikoagulationspeptider.
DK183789A (da)	1989-10-19	2-alkyl-3-benzoylbenzofuraner og laegemidler indeholdende disse
SE9001269D0 (sv)	1990-04-06	2-substituted n,n-ditrimethoxybenzoyl piperazines,a preparation process of the same and therapeutic compositions containing them
DK659089A (da)	1989-12-22	Mevalonolactoner af pyrazolopyridintypen
BR9405997A (pt)	1995-12-19	Composições antitumorais e métodos de tratamento
ATE134371T1 (de)	1996-03-15	Fungizide furanonderivate
DE3781986D1 (de)	1992-11-05	Substituierte chinoxaline.
DK509186A (da)	1987-04-26	1,4-dihydropyridinderivater og laegemiddel indeholdende saadanne derivater
DE69102563D1 (de)	1994-07-28	Thiocarbamoylacetonitrile.
NO923992D0 (no)	1992-10-14	Farmasoeytiske blandinger inneholdende triazolderivater for rektal administrering