NO932325L - Nye benzodiazepinderivater - Google Patents
Nye benzodiazepinderivaterInfo
- Publication number
- NO932325L NO932325L NO93932325A NO932325A NO932325L NO 932325 L NO932325 L NO 932325L NO 93932325 A NO93932325 A NO 93932325A NO 932325 A NO932325 A NO 932325A NO 932325 L NO932325 L NO 932325L
- Authority
- NO
- Norway
- Prior art keywords
- membered
- receptor
- cck
- substituted aryl
- new benzodiazepine
- Prior art date
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 150000001557 benzodiazepines Chemical class 0.000 title 1
- 108010089448 Cholecystokinin B Receptor Proteins 0.000 abstract 3
- 102100036016 Gastrin/cholecystokinin type B receptor Human genes 0.000 abstract 2
- 125000002950 monocyclic group Chemical group 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 102000052874 Gastrin receptors Human genes 0.000 abstract 1
- 108010079943 Pentagastrin Proteins 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- ANRIQLNBZQLTFV-DZUOILHNSA-N pentagastrin Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1[C]2C=CC=CC2=NC=1)NC(=O)CCNC(=O)OC(C)(C)C)CCSC)C(N)=O)C1=CC=CC=C1 ANRIQLNBZQLTFV-DZUOILHNSA-N 0.000 abstract 1
- 229960000444 pentagastrin Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Nytt benzodiazepinderivat representert ved generell formel (I) et farmasøytisk akseptabelt salt derav, et farmasøytisk preparat derav, og en fremgangsmåte for frem- stilling av dette. I formel (I) betegner R1 eventuelt substituert aryl, 5-leddet monosyklisk gruppe, 6-leddet monosyklisk gruppe eller aromatisk, heterosyklisk gruppe om- fattende 5-leddede og 6-leddede ringer; og R2 betegner eventuelt sub- stituert aryl. Forbindelsen (I) har en CCK-B-reseptorantagonisme og en virkning til å inhibere pentagastrin- stimulert magesekresjon og er således anvendbar ved behandling og forhind- ring av sykdommer hvori en CCK-B- reseptor og en gastrinreseptor deltar,
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP41826390 | 1990-12-25 | ||
| JP11121691 | 1991-02-20 | ||
| JP28205691 | 1991-10-02 | ||
| PCT/JP1991/001720 WO1992011246A1 (en) | 1990-12-25 | 1991-12-17 | Novel benzodiazepine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO932325D0 NO932325D0 (no) | 1993-06-24 |
| NO932325L true NO932325L (no) | 1993-06-24 |
Family
ID=27467860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO93932325A NO932325L (no) | 1990-12-25 | 1993-06-24 | Nye benzodiazepinderivater |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO932325L (no) |
-
1993
- 1993-06-24 NO NO93932325A patent/NO932325L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO932325D0 (no) | 1993-06-24 |
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