NO934399L - Tioesterderivater av 3'-O-propargyl-trifluortymidin, fremgangsmåte for fremstilling samt anvendelse av slike - Google Patents
Tioesterderivater av 3'-O-propargyl-trifluortymidin, fremgangsmåte for fremstilling samt anvendelse av slikeInfo
- Publication number
- NO934399L NO934399L NO934399A NO934399A NO934399L NO 934399 L NO934399 L NO 934399L NO 934399 A NO934399 A NO 934399A NO 934399 A NO934399 A NO 934399A NO 934399 L NO934399 L NO 934399L
- Authority
- NO
- Norway
- Prior art keywords
- phenyl group
- group substituted
- groups
- trifluorothymidine
- propargyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Tioesterderivat av 3 ' -0-propargyl-trifluortymidin, anvendelig som et middel mot kreft. Tioesterderivatet er representert ved formel ( l ) : O d) OCH2C = hvori R1 representerer en fenylgruppe, en fenylgruppe substituert med l til 5 halogenatomer, en fenylgruppe substi- tuert med l til 5 Cj-C^alkylgrupper, en fenylgruppe substituert med l til 5 Cj- 0,,-alkoksygrupper, en fenylgruppe substituert med l til 5 Cj-C^-alkyl- tiogrupper, en fenylgruppe substituert med l til 5 Cj-Cj-alkanoylaminogrupper, en fenylgruppe substituert med l til 5 trifluormetylgrupper, en furylgruppe, en tienylgruppe eller en pyrrolyl- gruppe.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32633292 | 1992-12-07 | ||
| JP17971693 | 1993-07-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO934399D0 NO934399D0 (no) | 1993-12-03 |
| NO934399L true NO934399L (no) | 1994-06-08 |
Family
ID=26499485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO934399A NO934399L (no) | 1992-12-07 | 1993-12-03 | Tioesterderivater av 3'-O-propargyl-trifluortymidin, fremgangsmåte for fremstilling samt anvendelse av slike |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0601520A1 (no) |
| KR (1) | KR940014390A (no) |
| CN (1) | CN1094409A (no) |
| FI (1) | FI935444L (no) |
| NO (1) | NO934399L (no) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3469533D1 (en) * | 1983-05-23 | 1988-04-07 | Taiho Pharmaceutical Co Ltd | Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same |
| JP2522926B2 (ja) * | 1987-01-20 | 1996-08-07 | 大鵬薬品工業株式会社 | ２′−デオキシ−５−トリフルオロメチルウリジン誘導体の製造方法 |
| JP2631223B2 (ja) * | 1988-04-12 | 1997-07-16 | 大鵬薬品工業株式会社 | ５−置換−２´−デオキシウリジン類 |
| KR950004900B1 (ko) * | 1991-06-07 | 1995-05-15 | 미쯔이 도오아쯔 가가쿠 가부시기가이샤 | 트리플루오로티미딘 유도체, 그 제조 방법 및 그것을 유효 성분으로 하는 제암제 |
-
1993
- 1993-12-03 FI FI935444A patent/FI935444L/fi not_active Application Discontinuation
- 1993-12-03 NO NO934399A patent/NO934399L/no unknown
- 1993-12-06 KR KR1019930026546A patent/KR940014390A/ko not_active Ceased
- 1993-12-06 EP EP93119638A patent/EP0601520A1/en not_active Withdrawn
- 1993-12-07 CN CN93120860A patent/CN1094409A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI935444A0 (fi) | 1993-12-03 |
| FI935444A7 (fi) | 1994-06-08 |
| NO934399D0 (no) | 1993-12-03 |
| FI935444L (fi) | 1994-06-08 |
| EP0601520A1 (en) | 1994-06-15 |
| KR940014390A (ko) | 1994-07-18 |
| CN1094409A (zh) | 1994-11-02 |
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