NO940227L - Process for the preparation of intermediates for the synthesis of chiral thiazolidine-2,4-dione derivatives - Google Patents

Process for the preparation of intermediates for the synthesis of chiral thiazolidine-2,4-dione derivatives

Info

Publication number
NO940227L
NO940227L NO940227A NO940227A NO940227L NO 940227 L NO940227 L NO 940227L NO 940227 A NO940227 A NO 940227A NO 940227 A NO940227 A NO 940227A NO 940227 L NO940227 L NO 940227L
Authority
NO
Norway
Prior art keywords
preparation
intermediates
synthesis
dione derivatives
thiazolidine
Prior art date
Application number
NO940227A
Other languages
Norwegian (no)
Other versions
NO940227D0 (en
Inventor
George Joseph Quallich
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO940227D0 publication Critical patent/NO940227D0/en
Publication of NO940227L publication Critical patent/NO940227L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Fremgangsmåte for stereoselektiv fremstilling av mellomprodukter for fremstilling av kraftige, chirale tiazolidin- 2,4-dion-hypoglykemiske midler.Process for stereoselective preparation of intermediates for preparation of potent chiral thiazolidine-2,4-dione hypoglycemic agents.

NO940227A 1991-07-22 1994-01-21 Process for the preparation of intermediates for the synthesis of chiral thiazolidine-2,4-dione derivatives NO940227L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73356491A 1991-07-22 1991-07-22
PCT/US1992/005433 WO1993002060A1 (en) 1991-07-22 1992-07-01 Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives

Publications (2)

Publication Number Publication Date
NO940227D0 NO940227D0 (en) 1994-01-21
NO940227L true NO940227L (en) 1994-01-21

Family

ID=24948157

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940227A NO940227L (en) 1991-07-22 1994-01-21 Process for the preparation of intermediates for the synthesis of chiral thiazolidine-2,4-dione derivatives

Country Status (21)

Country Link
US (1) US5512689A (en)
EP (1) EP0595868B1 (en)
JP (1) JP2671962B2 (en)
AT (1) ATE173728T1 (en)
AU (1) AU660701B2 (en)
CA (1) CA2111445C (en)
DE (1) DE69227689T2 (en)
DK (1) DK0595868T3 (en)
ES (1) ES2123562T3 (en)
FI (1) FI940306A0 (en)
HU (1) HUT70412A (en)
IE (1) IE922359A1 (en)
IL (1) IL102574A (en)
MX (1) MX9204278A (en)
MY (1) MY131277A (en)
NO (1) NO940227L (en)
NZ (1) NZ243651A (en)
PT (1) PT100710B (en)
TW (1) TW199891B (en)
WO (1) WO1993002060A1 (en)
ZA (1) ZA925469B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2111446C (en) * 1991-07-22 1997-12-16 George J. Quallich Chiral intermediates for the preparation of antidiabetics thiazoles
FR2699172B1 (en) * 1992-12-11 1995-01-20 Adir New derivatives of 4-methyl-1,3-oxazole, their preparation process and the pharmaceutical compositions containing them.
TW416958B (en) * 1993-05-14 2001-01-01 Pfizer Enantioselective oxazaborolidine catalysts
CA2383347A1 (en) * 1999-08-31 2001-03-08 Maxia Pharmaceuticals, Inc. Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes
WO2002072009A2 (en) 2001-03-07 2002-09-19 Maxia Pharmaceuticals, Inc. Heterocyclic derivatives for the treatment of cancer and other proliferative diseases
US7265139B2 (en) * 2001-03-08 2007-09-04 Incyte San Diego Inc. RXR activating molecules
CA2340824A1 (en) * 2001-03-14 2002-09-14 Ibm Canada Limited-Ibm Canada Limitee Method and system for application behavior analysis
EP1421061A4 (en) * 2001-08-17 2004-12-22 Incyte San Diego Inc Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia
JP2005513026A (en) * 2001-11-15 2005-05-12 インサイト サン ディエゴ インコーポレイテッド Hypercholesterolemia, dyslipidemia and other metabolic disorders; N-substituted heterocycles to treat cancer and other diseases
US7102000B2 (en) * 2002-03-08 2006-09-05 Incyte San Diego Inc. Heterocyclic amide derivatives for the treatment of diabetes and other diseases
US7196108B2 (en) * 2002-03-08 2007-03-27 Incyte San Diego Inc. Bicyclic heterocycles for the treatment of diabetes and other diseases
US20050014767A1 (en) * 2003-01-29 2005-01-20 Magnus Pfahl Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases
AU2004232326A1 (en) * 2003-04-18 2004-11-04 Incyte San Diego Incorporated Substituted isochroman compounds for the treatment of metabolic disorders, cancer and other diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943635A (en) * 1987-08-27 1990-07-24 President & Fellows Of Harvard College Enantioselective reduction of ketones
US5036079A (en) * 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
TW222626B (en) * 1991-07-22 1994-04-21 Pfizer

Also Published As

Publication number Publication date
IE922359A1 (en) 1993-01-27
IL102574A (en) 1996-07-23
WO1993002060A1 (en) 1993-02-04
JP2671962B2 (en) 1997-11-05
FI940306L (en) 1994-01-21
PT100710A (en) 1993-09-30
HU9400188D0 (en) 1994-05-30
US5512689A (en) 1996-04-30
DE69227689T2 (en) 1999-04-22
IL102574A0 (en) 1993-01-14
CA2111445C (en) 1997-02-18
FI940306A7 (en) 1994-01-21
ATE173728T1 (en) 1998-12-15
ES2123562T3 (en) 1999-01-16
AU2306292A (en) 1993-02-23
ZA925469B (en) 1994-01-21
NO940227D0 (en) 1994-01-21
AU660701B2 (en) 1995-07-06
TW199891B (en) 1993-02-11
EP0595868A1 (en) 1994-05-11
DK0595868T3 (en) 1999-08-09
FI940306A0 (en) 1994-01-21
NZ243651A (en) 1994-01-26
MY131277A (en) 2007-07-31
DE69227689D1 (en) 1999-01-07
PT100710B (en) 1999-07-30
MX9204278A (en) 1994-03-31
EP0595868B1 (en) 1998-11-25
HUT70412A (en) 1995-10-30
CA2111445A1 (en) 1993-02-04
JPH07502017A (en) 1995-03-02

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