NO940710L - Nye Esculetin-derivater og farmasöytisk blanding - Google Patents
Nye Esculetin-derivater og farmasöytisk blandingInfo
- Publication number
- NO940710L NO940710L NO940710A NO940710A NO940710L NO 940710 L NO940710 L NO 940710L NO 940710 A NO940710 A NO 940710A NO 940710 A NO940710 A NO 940710A NO 940710 L NO940710 L NO 940710L
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen atom
- new
- group
- independently
- general formula
- Prior art date
Links
- ILEDWLMCKZNDJK-UHFFFAOYSA-N esculetin Chemical class C1=CC(=O)OC2=C1C=C(O)C(O)=C2 ILEDWLMCKZNDJK-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 linolyl Chemical group 0.000 abstract 2
- YQTCQNIPQMJNTI-UHFFFAOYSA-N 2,2-dimethylpropan-1-one Chemical group CC(C)(C)[C]=O YQTCQNIPQMJNTI-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 125000000400 lauroyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 abstract 1
- 125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000003696 stearoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6616493 | 1993-03-02 | ||
| JP5351659A JPH06312925A (ja) | 1993-03-02 | 1993-12-27 | 軟骨保護剤及び新規エスクレチン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO940710D0 NO940710D0 (no) | 1994-03-01 |
| NO940710L true NO940710L (no) | 1994-09-05 |
Family
ID=26407334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940710A NO940710L (no) | 1993-03-02 | 1994-03-01 | Nye Esculetin-derivater og farmasöytisk blanding |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5455268A (fr) |
| EP (1) | EP0614896B1 (fr) |
| JP (1) | JPH06312925A (fr) |
| KR (1) | KR0135723B1 (fr) |
| CN (1) | CN1147297C (fr) |
| AU (1) | AU660870B2 (fr) |
| CA (1) | CA2116617C (fr) |
| DE (1) | DE69415570T2 (fr) |
| NO (1) | NO940710L (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4323409A1 (de) * | 1993-07-13 | 1995-01-19 | Boehringer Mannheim Gmbh | Verwendung von Cumarinen und Carbostyrilen als PLA¶2¶-Inhibitoren, neue Cumarine und Carbostyrile, Verfahren zu ihrer Herstellung und Arzneimittel |
| CN1053193C (zh) * | 1993-11-15 | 2000-06-07 | 吴羽化学工业株式会社 | 七叶亭衍生物和其制造方法与用途及其医药组合物 |
| JP2902318B2 (ja) * | 1994-12-28 | 1999-06-07 | 呉羽化学工業株式会社 | エスクレチン誘導体、その製造方法及びマトリックスメタロプロテアーゼ阻害剤 |
| GB9609024D0 (en) * | 1996-05-01 | 1996-07-03 | Idg Uk Ltd | Compounds |
| WO1998004572A1 (fr) * | 1996-07-31 | 1998-02-05 | Kureha Chemical Industry Co., Ltd. | Nouveaux derives de coumarine et glycosides, et procedes pour la preparation de ces composes |
| WO1998055644A1 (fr) * | 1997-06-04 | 1998-12-10 | Freeman Group Of Hospitals Nhs Trust | Identification de salmonella |
| JP2000119181A (ja) | 1998-10-06 | 2000-04-25 | Kureha Chem Ind Co Ltd | エスクレチン及びその誘導体の放出制御経口製剤 |
| US7067144B2 (en) * | 1998-10-20 | 2006-06-27 | Omeros Corporation | Compositions and methods for systemic inhibition of cartilage degradation |
| CN1186336C (zh) * | 2002-08-29 | 2005-01-26 | 成都迪康药物研究所 | 秦皮总香豆素的制备方法及其在制药中的应用 |
| WO2005091960A2 (fr) * | 2004-03-05 | 2005-10-06 | Rush University Medical Center | Procede visant a inhiber la degradation du cartilage fibreux |
| CN100428934C (zh) * | 2006-09-07 | 2008-10-29 | 中国人民解放军第二军医大学 | 香豆素类化合物在制备诱导神经干细胞定向分化药物中的应用 |
| CN104557831B (zh) * | 2015-02-11 | 2016-03-23 | 施维雅(青岛)生物制药有限公司 | 七叶内酯衍生物及其制备方法和应用 |
| CN119606945B (zh) * | 2025-02-11 | 2025-05-06 | 广州白云山星群(药业)股份有限公司 | 夏桑菊潜在活性成分4-甲基七叶亭在制备防治糖尿病药物中的应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2276819A1 (fr) * | 1974-07-05 | 1976-01-30 | Fabre Sa Pierre | Facteurs p lipophile a action anti-inflammatoire locale utilisables dans le traitement de syndromes dermatologiques |
-
1993
- 1993-12-27 JP JP5351659A patent/JPH06312925A/ja active Pending
-
1994
- 1994-02-28 CA CA002116617A patent/CA2116617C/fr not_active Expired - Fee Related
- 1994-02-28 KR KR1019940003709A patent/KR0135723B1/ko not_active Expired - Fee Related
- 1994-03-01 AU AU56438/94A patent/AU660870B2/en not_active Ceased
- 1994-03-01 DE DE69415570T patent/DE69415570T2/de not_active Expired - Fee Related
- 1994-03-01 NO NO940710A patent/NO940710L/no unknown
- 1994-03-01 EP EP94103036A patent/EP0614896B1/fr not_active Expired - Lifetime
- 1994-03-02 US US08/204,445 patent/US5455268A/en not_active Expired - Lifetime
- 1994-03-02 CN CNB941022374A patent/CN1147297C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06312925A (ja) | 1994-11-08 |
| DE69415570D1 (de) | 1999-02-11 |
| KR0135723B1 (ko) | 1998-04-23 |
| US5455268A (en) | 1995-10-03 |
| CA2116617A1 (fr) | 1994-09-03 |
| AU660870B2 (en) | 1995-07-06 |
| EP0614896B1 (fr) | 1998-12-30 |
| KR940021058A (ko) | 1994-10-17 |
| EP0614896A1 (fr) | 1994-09-14 |
| DE69415570T2 (de) | 1999-06-24 |
| AU5643894A (en) | 1994-09-15 |
| CN1147297C (zh) | 2004-04-28 |
| NO940710D0 (no) | 1994-03-01 |
| CN1101259A (zh) | 1995-04-12 |
| CA2116617C (fr) | 2001-02-20 |
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