NO941123L - Neuromedin-B-reseptor-antagonister - Google Patents

Neuromedin-B-reseptor-antagonister

Info

Publication number
NO941123L
NO941123L NO941123A NO941123A NO941123L NO 941123 L NO941123 L NO 941123L NO 941123 A NO941123 A NO 941123A NO 941123 A NO941123 A NO 941123A NO 941123 L NO941123 L NO 941123L
Authority
NO
Norway
Prior art keywords
neuromedin
receptor antagonists
nal
cys
receptor
Prior art date
Application number
NO941123A
Other languages
English (en)
Other versions
NO941123D0 (no
Inventor
David Howard Coy
John E Taylor
Original Assignee
Univ Tulane
Biomeasure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/078,419 external-priority patent/US5462926A/en
Application filed by Univ Tulane, Biomeasure Inc filed Critical Univ Tulane
Publication of NO941123D0 publication Critical patent/NO941123D0/no
Publication of NO941123L publication Critical patent/NO941123L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det beskrives en fremgangsmåte for selektiv inhibering av biokjemisk aktivitet indusert i celler av neuromedin B. Fremgangsmåten innbefatter det trinn at celler som inneholder neuromedin B-reseptorer bringes i kontakt med et cyklisk oktapeptid, D-Nal-Cys-Tyr-D-Trp-Lys-Val-Cys-Nal-NH2, eller en analog derav.
NO941123A 1992-07-27 1994-03-25 Neuromedin-B-reseptor-antagonister NO941123L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91953792A 1992-07-27 1992-07-27
US08/078,419 US5462926A (en) 1992-07-27 1993-06-17 Neuromedin B receptor antagonists which demonstrate selectivity
PCT/US1993/007036 WO1994002163A1 (en) 1992-07-27 1993-07-27 Neuromedin b receptor antagonists

Publications (2)

Publication Number Publication Date
NO941123D0 NO941123D0 (no) 1994-03-25
NO941123L true NO941123L (no) 1994-03-25

Family

ID=25442276

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941123A NO941123L (no) 1992-07-27 1994-03-25 Neuromedin-B-reseptor-antagonister

Country Status (10)

Country Link
EP (1) EP0606463B1 (no)
JP (1) JP3553062B2 (no)
AT (1) ATE206307T1 (no)
AU (1) AU672426B2 (no)
CA (1) CA2118588A1 (no)
DE (1) DE69330868T2 (no)
DK (1) DK0606463T3 (no)
ES (1) ES2162822T3 (no)
NO (1) NO941123L (no)
WO (1) WO1994002163A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5569741A (en) * 1992-07-27 1996-10-29 Biomeasure, Inc. Cyclic octapeptide neuromedin B receptor antagonists
US5846934A (en) * 1996-02-20 1998-12-08 American Cyanamid Company Pure somatostatin antagonist and methods of use thereof
JPH09328499A (ja) * 1996-02-20 1997-12-22 American Cyanamid Co 純粋なソマトスタチンアンタゴニストおよびその使用方法
DK1165613T3 (da) 1999-03-29 2008-08-25 Procter & Gamble Melanocortinreceptorligander
US7862825B2 (en) 2007-02-21 2011-01-04 Mladen Vranic Method of controlling tight blood glucose by somatostatin receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085913B2 (ja) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド 治療用ソマトスタチン同族体
JP2809403B2 (ja) * 1987-07-07 1998-10-08 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 治療用ソマトスタチンアナログ化合物
WO1989004646A1 (en) * 1987-11-13 1989-06-01 Jefferies Steven R Bone repair material and delayed drug delivery
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
JP2882679B2 (ja) * 1989-04-26 1999-04-12 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 線状ソマトスタチン類似体
WO1991004040A1 (en) * 1989-09-15 1991-04-04 Biomeasure, Inc. Treatment of colon cancer
ES2091907T3 (es) * 1989-12-08 1996-11-16 Univ Tulane Analogos octapeptidos de somatostina con una threonina en la sexta posicion.

Also Published As

Publication number Publication date
WO1994002163A1 (en) 1994-02-03
JPH06511495A (ja) 1994-12-22
EP0606463B1 (en) 2001-10-04
JP3553062B2 (ja) 2004-08-11
DE69330868T2 (de) 2002-04-25
EP0606463A1 (en) 1994-07-20
AU672426B2 (en) 1996-10-03
EP0606463A4 (en) 1997-09-24
NO941123D0 (no) 1994-03-25
ES2162822T3 (es) 2002-01-16
AU4787193A (en) 1994-02-14
DK0606463T3 (da) 2001-12-03
DE69330868D1 (de) 2001-11-08
CA2118588A1 (en) 1994-02-03
ATE206307T1 (de) 2001-10-15

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