NO941135L - Tiazolpyrimidin derivater - Google Patents

Tiazolpyrimidin derivater

Info

Publication number
NO941135L
NO941135L NO941135A NO941135A NO941135L NO 941135 L NO941135 L NO 941135L NO 941135 A NO941135 A NO 941135A NO 941135 A NO941135 A NO 941135A NO 941135 L NO941135 L NO 941135L
Authority
NO
Norway
Prior art keywords
derivatives
pyrimidine derivatives
salts
thiazole
thiazole pyrimidine
Prior art date
Application number
NO941135A
Other languages
English (en)
Other versions
NO941135D0 (no
Inventor
Hiroo Matsumoto
Noriko Tanaka
Kiyoshi Nakayama
Haruko Chatani
Michio Iwahana
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of NO941135D0 publication Critical patent/NO941135D0/no
Publication of NO941135L publication Critical patent/NO941135L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Tiazolpyrimidinderivater med formel og salter derav hvor R1, R2 R4, R5 og n har en rekke angitte betydninger. Derivatene er kjennetegnet ved en karboksamidrest substituert med R* og R5. Derivatene og saltene derav utviser antiangiogen aktivitet og kan anvendes for behandling og helbredelse av sykdommer relatert til angiogenese, inkluderende diabetisk retinopati, forskjellige kroniske inflammasjonstilstander, vekst eller metastaser av maligne faste tumorer, reumatisme og psoriasis.
NO941135A 1993-04-01 1994-03-28 Tiazolpyrimidin derivater NO941135L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11087793 1993-04-01

Publications (2)

Publication Number Publication Date
NO941135D0 NO941135D0 (no) 1994-03-28
NO941135L true NO941135L (no) 1994-10-03

Family

ID=14546967

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941135A NO941135L (no) 1993-04-01 1994-03-28 Tiazolpyrimidin derivater

Country Status (9)

Country Link
US (1) US5599813A (no)
EP (1) EP0618208A1 (no)
CN (1) CN1100425A (no)
AU (1) AU672675B2 (no)
CA (1) CA2120395A1 (no)
FI (1) FI941487A7 (no)
NO (1) NO941135L (no)
PH (1) PH31256A (no)
TW (1) TW272193B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0994104A4 (en) * 1996-06-27 2001-09-12 Ono Pharmaceutical Co ARYL SULFIDE, SULFOXIDE AND SULPHONE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM AS AN ACTIVE INGREDIENT
EP1096955B9 (en) 1998-07-13 2006-07-05 Board of Regents, The University of Texas System Uses of antibodies to aminophospholipids for cancer treatment
EP1234585A3 (en) 1998-09-04 2004-01-21 The Regents Of The University Of Michigan Methods and compositions for the prevention or treatment of cancer
US6930101B1 (en) 1999-05-17 2005-08-16 The Regents Of The University Of California Thiazolopyrimidines useful as TNFα inhibitors
DE10112197A1 (de) * 2001-03-14 2002-09-19 Gruenenthal Gmbh Substituierte Pyrazolo- und Thiazolopyrimidine
DE60335383D1 (de) 2002-07-15 2011-01-27 Univ Texas Antikörper mit bindung an anionische phospholipide und aminophospholipide und ihre verwendung bei der behandlung von virusinfektionen
HRP20130459T1 (en) 2004-01-22 2013-06-30 University Of Miami Topical co-enzyme q10 formulations and methods of use
US7691888B2 (en) 2004-10-07 2010-04-06 Boehringer Ingelheim International Gmbh Thiazolyl-dihydro-indazole
WO2009060198A1 (en) 2007-11-09 2009-05-14 Peregrine Pharmaceuticals, Inc. Anti-vegf antibody compositions and methods
EP2323679A4 (en) 2008-07-25 2012-08-22 Univ Colorado CLIP INHIBITORS AND METHODS FOR MODULATING IMMUNE FUNCTION
CN101899058B (zh) * 2010-05-24 2012-05-23 中国人民解放军第四军医大学 一种噻唑并嘧啶化合物及其制备方法和应用
KR20140020972A (ko) * 2011-03-28 2014-02-19 에프. 호프만-라 로슈 아게 티아졸로피리미딘 화합물
US10786471B2 (en) 2017-02-06 2020-09-29 Massachusetts Institute Of Technology Methods and products related to glutaminase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1095524A (en) * 1976-01-19 1981-02-10 Robert E. Moser Antiinflammatory imidazothiazoles
FR2479831A1 (fr) * 1980-04-08 1981-10-09 Synthelabo Derives de thiazole, leur preparation et leur application en therapeutique
PL129612B1 (en) * 1980-07-24 1984-05-31 Rhone Poulenc Ind Process for preparing novel derivatives of 2,3,6,7-tetrahydrothiazole/3,2-a/pirymidin-5-one
US4347248A (en) * 1981-03-23 1982-08-31 American Cyanamid Company 2,3-Disubstituted-thiazolo[3,2-a]pyrimidines
US5082838A (en) * 1989-06-21 1992-01-21 Takeda Chemical Industries, Ltd. Sulfur-containing fused pyrimidine derivatives, their production and use

Also Published As

Publication number Publication date
US5599813A (en) 1997-02-04
FI941487L (fi) 1994-10-02
AU5925294A (en) 1994-10-06
EP0618208A1 (en) 1994-10-05
CN1100425A (zh) 1995-03-22
FI941487A7 (fi) 1994-10-02
PH31256A (en) 1998-06-18
CA2120395A1 (en) 1994-10-02
TW272193B (no) 1996-03-11
FI941487A0 (fi) 1994-03-30
AU672675B2 (en) 1996-10-10
NO941135D0 (no) 1994-03-28

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