NO942750L - Monomere og dimere fusjonsproteiner av antistoff-fragment - Google Patents

Monomere og dimere fusjonsproteiner av antistoff-fragment

Info

Publication number
NO942750L
NO942750L NO942750A NO942750A NO942750L NO 942750 L NO942750 L NO 942750L NO 942750 A NO942750 A NO 942750A NO 942750 A NO942750 A NO 942750A NO 942750 L NO942750 L NO 942750L
Authority
NO
Norway
Prior art keywords
fusion proteins
pct
antibody
antibody fragment
monomeric
Prior art date
Application number
NO942750A
Other languages
English (en)
Norwegian (no)
Other versions
NO942750D0 (no
Inventor
Andreas Pluckthun
Peter Pack
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO942750D0 publication Critical patent/NO942750D0/no
Publication of NO942750L publication Critical patent/NO942750L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO942750A 1992-01-23 1994-07-22 Monomere og dimere fusjonsproteiner av antistoff-fragment NO942750L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92101069 1992-01-23
PCT/EP1993/000082 WO1993015210A1 (en) 1992-01-23 1993-01-15 Monomeric and dimeric antibody-fragment fusion proteins

Publications (2)

Publication Number Publication Date
NO942750D0 NO942750D0 (no) 1994-07-22
NO942750L true NO942750L (no) 1994-09-13

Family

ID=8209260

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942750A NO942750L (no) 1992-01-23 1994-07-22 Monomere og dimere fusjonsproteiner av antistoff-fragment

Country Status (16)

Country Link
US (1) US5910573A (da)
EP (1) EP0654085B1 (da)
JP (2) JP3490437B2 (da)
KR (1) KR100254759B1 (da)
AT (1) ATE151113T1 (da)
AU (1) AU676150B2 (da)
CA (1) CA2128511C (da)
CZ (1) CZ287296B6 (da)
DE (1) DE69309472T2 (da)
DK (1) DK0654085T3 (da)
ES (1) ES2102007T3 (da)
GR (1) GR3023860T3 (da)
HU (1) HU215180B (da)
NO (1) NO942750L (da)
RU (1) RU2128709C1 (da)
WO (1) WO1993015210A1 (da)

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AU3410093A (en) 1993-09-01
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