NO943791L - 1,2-dihydro-2-okso-3-metylsulfonylaminometylpyridin - Google Patents
1,2-dihydro-2-okso-3-metylsulfonylaminometylpyridinInfo
- Publication number
- NO943791L NO943791L NO943791A NO943791A NO943791L NO 943791 L NO943791 L NO 943791L NO 943791 A NO943791 A NO 943791A NO 943791 A NO943791 A NO 943791A NO 943791 L NO943791 L NO 943791L
- Authority
- NO
- Norway
- Prior art keywords
- dihydro
- oxo
- metylsulfonylaminometylpyridin
- atoms
- represents alkyl
- Prior art date
Links
- BVNUZTLDFDCMDW-UHFFFAOYSA-N n-[(2-oxo-1h-pyridin-3-yl)methyl]methanesulfonamide Chemical compound CS(=O)(=O)NCC1=CC=CNC1=O BVNUZTLDFDCMDW-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- -1 1H-5-tetrazolyl Chemical group 0.000 abstract 1
- 102000005862 Angiotensin II Human genes 0.000 abstract 1
- 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010020571 Hyperaldosteronism Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
- 229950006323 angiotensin ii Drugs 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Nye 1,2-dihydro-2-okso-3-metyl-sulfonylaminometylpyridiner med formel. I. hvor Rbetyr alkyl med 1-5 C-atomer,. Rbetyr CN eller lH-5-tetrazolyl, og Rbetyr alkyl med 1-5 C-atomer eller syklopropylmetyl, samt salter derav har angiotensin II-antagonistiske egen-skaper og kan anvendes til behandling av hypertensjon, aldosteronisme og hjerteinsuffisiens.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4334308A DE4334308A1 (de) | 1993-10-08 | 1993-10-08 | 1,2-Dihydro-2-oxo-3-methylsulfonylaminomethyl-pyridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO943791D0 NO943791D0 (no) | 1994-10-07 |
| NO943791L true NO943791L (no) | 1995-04-10 |
Family
ID=6499685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO943791A NO943791L (no) | 1993-10-08 | 1994-10-07 | 1,2-dihydro-2-okso-3-metylsulfonylaminometylpyridin |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0647627A1 (no) |
| JP (1) | JPH07188171A (no) |
| KR (1) | KR950011410A (no) |
| CN (1) | CN1106387A (no) |
| AU (1) | AU7438694A (no) |
| CA (1) | CA2133804A1 (no) |
| CZ (1) | CZ240194A3 (no) |
| DE (1) | DE4334308A1 (no) |
| HU (1) | HUT70555A (no) |
| NO (1) | NO943791L (no) |
| PL (1) | PL305354A1 (no) |
| RU (1) | RU94036750A (no) |
| SK (1) | SK121494A3 (no) |
| ZA (1) | ZA947884B (no) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4336051A1 (de) * | 1993-10-22 | 1995-04-27 | Merck Patent Gmbh | 1,2-Dihydro-2-oxo-pyridine |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4129340A1 (de) * | 1991-09-04 | 1993-03-11 | Merck Patent Gmbh | 1,2-dihydro-2-oxopyridine |
-
1993
- 1993-10-08 DE DE4334308A patent/DE4334308A1/de not_active Withdrawn
-
1994
- 1994-09-24 EP EP94115091A patent/EP0647627A1/de not_active Withdrawn
- 1994-09-30 CZ CZ942401A patent/CZ240194A3/cs unknown
- 1994-09-30 AU AU74386/94A patent/AU7438694A/en not_active Abandoned
- 1994-10-04 JP JP6240018A patent/JPH07188171A/ja active Pending
- 1994-10-06 CN CN94117088A patent/CN1106387A/zh active Pending
- 1994-10-06 CA CA002133804A patent/CA2133804A1/en not_active Abandoned
- 1994-10-06 SK SK1214-94A patent/SK121494A3/sk unknown
- 1994-10-07 HU HU9402902A patent/HUT70555A/hu unknown
- 1994-10-07 KR KR1019940025680A patent/KR950011410A/ko not_active Withdrawn
- 1994-10-07 NO NO943791A patent/NO943791L/no unknown
- 1994-10-07 ZA ZA947884A patent/ZA947884B/xx unknown
- 1994-10-07 RU RU94036750/04A patent/RU94036750A/ru unknown
- 1994-10-07 PL PL94305354A patent/PL305354A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT70555A (en) | 1995-10-30 |
| CZ240194A3 (en) | 1995-04-12 |
| RU94036750A (ru) | 1996-09-10 |
| PL305354A1 (en) | 1995-04-18 |
| EP0647627A1 (de) | 1995-04-12 |
| CN1106387A (zh) | 1995-08-09 |
| HU9402902D0 (en) | 1995-02-28 |
| JPH07188171A (ja) | 1995-07-25 |
| DE4334308A1 (de) | 1995-04-13 |
| NO943791D0 (no) | 1994-10-07 |
| ZA947884B (en) | 1995-05-22 |
| KR950011410A (ko) | 1995-05-15 |
| SK121494A3 (en) | 1995-05-10 |
| CA2133804A1 (en) | 1995-04-09 |
| AU7438694A (en) | 1995-04-27 |
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