NO944249L - Transdermal administrering av oksybutynin - Google Patents

Transdermal administrering av oksybutynin

Info

Publication number
NO944249L
NO944249L NO944249A NO944249A NO944249L NO 944249 L NO944249 L NO 944249L NO 944249 A NO944249 A NO 944249A NO 944249 A NO944249 A NO 944249A NO 944249 L NO944249 L NO 944249L
Authority
NO
Norway
Prior art keywords
oxybutynin
permeation enhancer
skin
transdermal administration
relates
Prior art date
Application number
NO944249A
Other languages
English (en)
Other versions
NO944249D0 (no
Inventor
Eun Soo Lee
Diane E Nedberge
Su Il Yum
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of NO944249D0 publication Critical patent/NO944249D0/no
Publication of NO944249L publication Critical patent/NO944249L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Den foreliggende oppfinnelse vedrører den transdermale administrering av oksubutynin samt med en egnet permeasjonsforbedrer. Oppfinnelsen innbefatter en anordning for transdermal medikamentavgivelse omfattende en matriks som er innrettet til å plasseres i oksybutynin- og permeasjonsforbedreroverførende forhold til hudområdet. .Matriksen inneholder tilstrekkelige mengder av en permeasjonsforbedrer og oksybutynin, i kombinasjon, slik at oksybutyninet kontinuerlig kan administreres til huden over et forutbestemt tidsrom for oppnåelse av et virk- ningsfullt terapeutisk resultat. Oppfinnelsen vedrører også en fremgangsmåte for transdermal administrering av en terapeutisk virkningsfull oksybutyninmengde sammen med en hudpermeasjons-forbedrende mengde av en egnet permeasjonsforbedrer.
NO944249A 1992-05-13 1994-11-08 Transdermal administrering av oksybutynin NO944249L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88265292A 1992-05-13 1992-05-13
PCT/US1993/004518 WO1993023025A1 (en) 1992-05-13 1993-05-13 Transdermal administration of oxybutynin

Publications (2)

Publication Number Publication Date
NO944249D0 NO944249D0 (no) 1994-11-08
NO944249L true NO944249L (no) 1994-11-14

Family

ID=25381055

Family Applications (1)

Application Number Title Priority Date Filing Date
NO944249A NO944249L (no) 1992-05-13 1994-11-08 Transdermal administrering av oksybutynin

Country Status (15)

Country Link
US (2) US5411740A (no)
EP (1) EP0767659B1 (no)
JP (1) JP3786684B2 (no)
KR (1) KR950701516A (no)
AT (1) ATE185694T1 (no)
AU (1) AU666735B2 (no)
CA (1) CA2132865C (no)
DE (1) DE69326848T2 (no)
ES (1) ES2137261T3 (no)
FI (1) FI945311A7 (no)
MX (1) MX9302812A (no)
NO (1) NO944249L (no)
NZ (1) NZ252598A (no)
WO (1) WO1993023025A1 (no)
ZA (1) ZA933349B (no)

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ZA933349B (en) 1994-06-15
JP3786684B2 (ja) 2006-06-14
US5411740A (en) 1995-05-02
EP0767659B1 (en) 1999-10-20
ATE185694T1 (de) 1999-11-15
NZ252598A (en) 1997-01-29
CA2132865A1 (en) 1993-11-25
WO1993023025A1 (en) 1993-11-25
AU666735B2 (en) 1996-02-22
FI945311A0 (fi) 1994-11-11
US5500222A (en) 1996-03-19
DE69326848D1 (de) 1999-11-25
KR950701516A (ko) 1995-04-28
MX9302812A (es) 1993-11-01
DE69326848T2 (de) 2000-01-27
AU4247393A (en) 1993-12-13
EP0767659A1 (en) 1997-04-16
JPH08502952A (ja) 1996-04-02
NO944249D0 (no) 1994-11-08
FI945311L (fi) 1994-11-11
FI945311A7 (fi) 1994-11-11
CA2132865C (en) 2003-12-02
ES2137261T3 (es) 1999-12-16

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