NO944892L - N-substituerte 3-azabicyklo (3.2.0) hepatanderivater som neuroleptika osv. - Google Patents

N-substituerte 3-azabicyklo (3.2.0) hepatanderivater som neuroleptika osv.

Info

Publication number
NO944892L
NO944892L NO944892A NO944892A NO944892L NO 944892 L NO944892 L NO 944892L NO 944892 A NO944892 A NO 944892A NO 944892 A NO944892 A NO 944892A NO 944892 L NO944892 L NO 944892L
Authority
NO
Norway
Prior art keywords
pct
neuroleptics
hepatane
azabicyclo
derivatives
Prior art date
Application number
NO944892A
Other languages
English (en)
Other versions
NO944892D0 (no
NO305176B1 (no
Inventor
Gerd Steiner
Liliane Unger
Berthold Behl
Hans-Jurgen Teschendorf
Rainer Munschauer
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO944892D0 publication Critical patent/NO944892D0/no
Publication of NO944892L publication Critical patent/NO944892L/no
Publication of NO305176B1 publication Critical patent/NO305176B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO944892A 1992-06-19 1994-12-16 N-substituerte 3-azabicyklo [3.2.0] heptanderivater og anvendelse derav NO305176B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4219974 1992-06-19
DE4243287A DE4243287A1 (de) 1992-06-19 1992-12-21 N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
PCT/EP1993/001438 WO1994000458A1 (de) 1992-06-19 1993-06-08 N-substituierte 3-azabicyclo[3.2.0]heptanderivate als neuroleptika usw.
CN93114691A CN1039996C (zh) 1992-06-19 1993-12-11 N-取代氮杂双环庚烷衍生物及其用途

Publications (3)

Publication Number Publication Date
NO944892D0 NO944892D0 (no) 1994-12-16
NO944892L true NO944892L (no) 1995-02-13
NO305176B1 NO305176B1 (no) 1999-04-12

Family

ID=36940125

Family Applications (1)

Application Number Title Priority Date Filing Date
NO944892A NO305176B1 (no) 1992-06-19 1994-12-16 N-substituerte 3-azabicyklo [3.2.0] heptanderivater og anvendelse derav

Country Status (24)

Country Link
US (1) US5475105A (no)
EP (1) EP0647231B1 (no)
JP (1) JP3171258B2 (no)
CN (2) CN1042133C (no)
AT (1) ATE157366T1 (no)
AU (1) AU671130B2 (no)
BG (1) BG62350B2 (no)
CA (1) CA2138289C (no)
CZ (1) CZ288787B6 (no)
DE (2) DE4243287A1 (no)
DK (1) DK0647231T3 (no)
ES (1) ES2107035T3 (no)
FI (1) FI108726B (no)
GR (1) GR3025095T3 (no)
HU (1) HU218911B (no)
IL (1) IL105989A (no)
NO (1) NO305176B1 (no)
NZ (1) NZ253121A (no)
PH (1) PH30466A (no)
RU (1) RU2135503C1 (no)
SG (1) SG44782A1 (no)
TW (1) TW408126B (no)
WO (1) WO1994000458A1 (no)
ZA (1) ZA934374B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4427648A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
DE4338396A1 (de) * 1993-11-10 1995-05-11 Basf Ag N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4427647A1 (de) * 1994-08-04 1996-02-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19960074A1 (de) * 1999-12-13 2001-06-21 Basf Ag Neues Salz von Belaperidone und dessen Modifikationen
WO2002014295A1 (fr) * 2000-08-16 2002-02-21 Elena Alexandrovna Izakson Derives de thiazines de la formule generale (1) manifestant une action antibacterienne et antivirale
JP4754570B2 (ja) * 2004-10-14 2011-08-24 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンd3受容体の調節に応答する障害の治療に好適なアザビシクロヘプチル化合物
US20060199768A1 (en) * 2005-03-07 2006-09-07 University Of North Carolina At Chapel Hill Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens
DK2083811T3 (en) 2006-11-22 2017-01-30 Clinical Res Ass Llc PROCEDURES FOR TREATING DOWNS SYNDROME, FRAGILT X SYNDROME AND AUTISM
KR20100046047A (ko) * 2007-07-27 2010-05-04 액테리온 파마슈티칼 리미티드 2-아자-비시클로[3.3.0]옥탄 유도체
BR112017003745A2 (pt) 2014-08-29 2017-12-05 Tes Pharma S R L inibidores de semialdeído descarboxilase de ácido alfa-amino-beta-carboximucônico
CN112010851A (zh) * 2020-06-30 2020-12-01 浙江美诺华药物化学有限公司 一种莫西沙星盐酸盐的制备方法
CR20230437A (es) * 2021-03-17 2023-10-16 Hoffmann La Roche Nuevos derivados de tiazolopirimidinona

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155668A (en) * 1960-04-11 1964-11-03 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl)-lower-alkyl]-tertiary amines and intermediates therefor
US3328390A (en) * 1962-02-27 1967-06-27 Tri Kem Corp Certain azabicycloalkane compounds
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
SU1004389A1 (ru) * 1981-07-29 1983-03-15 Институт Органической Химии Ан Усср Способ получени производных тиазоло/3,4-а/пиримидинов
US4540318A (en) * 1982-07-29 1985-09-10 Robert Bosch, Gmbh Rotary electrical tool with speed control, especially drill
DE3228303A1 (de) * 1982-07-29 1984-02-02 Robert Bosch Gmbh, 7000 Stuttgart Elektrische motorregelung
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles

Also Published As

Publication number Publication date
FI108726B (fi) 2002-03-15
ZA934374B (en) 1994-12-19
CZ323794A3 (en) 1995-05-17
PH30466A (en) 1997-05-28
ATE157366T1 (de) 1997-09-15
WO1994000458A1 (de) 1994-01-06
IL105989A0 (en) 1993-10-20
BG62350B2 (bg) 1999-08-31
EP0647231A1 (de) 1995-04-12
JP3171258B2 (ja) 2001-05-28
DE4243287A1 (de) 1993-12-23
CN1087341A (zh) 1994-06-01
EP0647231B1 (de) 1997-08-27
HU218911B (hu) 2000-12-28
DE59307217D1 (de) 1997-10-02
CA2138289A1 (en) 1994-01-06
DK0647231T3 (da) 1997-09-29
CA2138289C (en) 2004-03-02
GR3025095T3 (en) 1998-01-30
CN1105358A (zh) 1995-07-19
RU95105435A (ru) 1996-11-20
HUT71351A (en) 1995-11-28
CN1042133C (zh) 1999-02-17
NO944892D0 (no) 1994-12-16
FI945957L (fi) 1994-12-19
TW408126B (en) 2000-10-11
CN1039996C (zh) 1998-09-30
ES2107035T3 (es) 1997-11-16
JPH07507771A (ja) 1995-08-31
SG44782A1 (en) 1997-12-19
CZ288787B6 (cs) 2001-09-12
RU2135503C1 (ru) 1999-08-27
US5475105A (en) 1995-12-12
IL105989A (en) 1997-02-18
FI945957A0 (fi) 1994-12-19
AU4323893A (en) 1994-01-24
NO305176B1 (no) 1999-04-12
AU671130B2 (en) 1996-08-15
NZ253121A (en) 1995-12-21

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