NO950143L - Derivatives of antibiotic macrolides with 16-membered ring - Google Patents
Derivatives of antibiotic macrolides with 16-membered ringInfo
- Publication number
- NO950143L NO950143L NO950143A NO950143A NO950143L NO 950143 L NO950143 L NO 950143L NO 950143 A NO950143 A NO 950143A NO 950143 A NO950143 A NO 950143A NO 950143 L NO950143 L NO 950143L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- membered ring
- antibiotic macrolides
- macrolides
- antibiotic
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title 1
- 239000003120 macrolide antibiotic agent Substances 0.000 title 1
- 229940041033 macrolides Drugs 0.000 title 1
- QRPHLEPFYLNRDA-NLGRAQRVSA-N 2-[(4r,5s,6s,7r,9r,11e,13e,15r,16r)-6-[(2r,3r,4s,5s,6r)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,1 Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@@H]1O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]1O QRPHLEPFYLNRDA-NLGRAQRVSA-N 0.000 abstract 1
- OBUIQEYZGMZXPJ-NPQHDNJNSA-N 2-[(4r,5s,6s,7r,9r,11e,13e,15s,16r)-6-[(2s,3r,4s,6r)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-5,9,13,15-tetramethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde Chemical compound O=CC[C@H]1C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@H](C)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)C[C@@H](C)O1 OBUIQEYZGMZXPJ-NPQHDNJNSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- CFMSCYSETWZXRS-UHFFFAOYSA-N Lactenocin Natural products O=CCC1CC(C)C(=O)C=CC(C)=CC(COC2C(C(O)C(O)C(C)O2)OC)C(CC)OC(=O)CC(O)C(C)C1OC1OC(C)C(O)C(N(C)C)C1O CFMSCYSETWZXRS-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 206010028470 Mycoplasma infections Diseases 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- CFMSCYSETWZXRS-SNPFKJFCSA-N lactenocin Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@@H]1[C@H]([C@@H](O)[C@@H](O)[C@@H](C)O1)OC)CC)C1O[C@@H](C)[C@@H](O)[C@@H](N(C)C)[C@@H]1O CFMSCYSETWZXRS-SNPFKJFCSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229950005855 repromicin Drugs 0.000 abstract 1
- IUPCWCLVECYZRV-JZMZINANSA-N rosaramicin Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H]([C@@H]2O[C@@]2(C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O IUPCWCLVECYZRV-JZMZINANSA-N 0.000 abstract 1
- 229950001447 rosaramicin Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår derivater av de 16-leddede ring-raakrolid antibiotikaene rosaramicin, repromicin, 5- mycaminosyltylonolid, desmycosin, lactenocin, 0- dmetyllaktenocin, cirramycin Aj og 23-deoksymycamino- syltylonolid som er nyttige mot bakterie- og roykoplasma- patogener hos dyr. Videre omfattes et farmasøytisk preparat av derivatene og anvendelse av dette for behandling av bakterie- og mykoplasma-infeksjoner hos dyr.BACKGROUND OF THE INVENTION The present invention relates to derivatives of the 16-membered ring-acrolide antibiotics rosaramicin, repromicin, 5-mycaminosyltylonolide, desmycosin, lactenocin, O-dimethylactocin, cirramycin A Furthermore, a pharmaceutical composition of the derivatives is included and its use for treating bacterial and mycoplasma infections in animals.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91424292A | 1992-07-15 | 1992-07-15 | |
| US99624392A | 1992-12-23 | 1992-12-23 | |
| PCT/US1993/005210 WO1994002496A1 (en) | 1992-07-15 | 1993-06-07 | Derivatives of 16-membered ring antibiotic macrolides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO950143D0 NO950143D0 (en) | 1995-01-13 |
| NO950143L true NO950143L (en) | 1995-01-13 |
Family
ID=27377388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO950143A NO950143L (en) | 1992-07-15 | 1995-01-13 | Derivatives of antibiotic macrolides with 16-membered ring |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO950143L (en) |
-
1995
- 1995-01-13 NO NO950143A patent/NO950143L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO950143D0 (en) | 1995-01-13 |
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