NO952336L - Insulin analoger - Google Patents

Insulin analoger

Info

Publication number
NO952336L
NO952336L NO952336A NO952336A NO952336L NO 952336 L NO952336 L NO 952336L NO 952336 A NO952336 A NO 952336A NO 952336 A NO952336 A NO 952336A NO 952336 L NO952336 L NO 952336L
Authority
NO
Norway
Prior art keywords
insulin analogues
analogues
resldle
hyperglycemic
ile
Prior art date
Application number
NO952336A
Other languages
English (en)
Other versions
NO952336D0 (no
Inventor
Ronald Eugene Chance
Li Fan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO952336L publication Critical patent/NO952336L/no
Publication of NO952336D0 publication Critical patent/NO952336D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Analoger av humanlnsulln Inneholdende et Ala, Gly, Val, leu. Ile og Pro resldle l posisjon 26 til B-kJeden. og eventuelt, med modifikasjoner l andre posisjoner, utviser modifiserte fyslsk-kjemiske og farmakokinetlske egenskaper. Disse analogene er nyttige for behandling av hyperglyceml på grunn av at de er stabile og har liten tendens for selv-aggregering.
NO952336A 1992-12-18 1995-06-13 Insulin analoger NO952336D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99565992A 1992-12-18 1992-12-18
PCT/US1993/012237 WO1994014461A1 (en) 1992-12-18 1993-12-15 Insulin analogs

Publications (2)

Publication Number Publication Date
NO952336L true NO952336L (no) 1995-06-13
NO952336D0 NO952336D0 (no) 1995-06-13

Family

ID=25542078

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952336A NO952336D0 (no) 1992-12-18 1995-06-13 Insulin analoger

Country Status (14)

Country Link
EP (1) EP0605983A3 (no)
JP (1) JPH08504820A (no)
CN (1) CN1094059A (no)
AU (1) AU680462B2 (no)
BR (1) BR9307687A (no)
CA (1) CA2151134A1 (no)
CZ (1) CZ158895A3 (no)
FI (1) FI953001A0 (no)
HU (1) HUT71583A (no)
MX (1) MX9307991A (no)
NO (1) NO952336D0 (no)
PL (1) PL310007A1 (no)
WO (1) WO1994014461A1 (no)
ZA (1) ZA939477B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559094A (en) * 1994-08-02 1996-09-24 Eli Lilly And Company AspB1 insulin analogs
CN1125081C (zh) * 1999-09-08 2003-10-22 中国科学院上海生物化学研究所 重组天然和新型人胰岛素及其制备方法
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
PH12011502708B1 (en) 2009-07-06 2017-11-10 Sanofi Aventis Deutschland Insulin preparations containing methionine
JP5832439B2 (ja) 2009-11-13 2015-12-16 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト、インスリン及びメチオニンを含む薬学的組成物
SG10201500871TA (en) 2009-11-13 2015-04-29 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
CN103179978A (zh) 2010-08-30 2013-06-26 赛诺菲-安万特德国有限公司 Ave0010用于制造供治疗2型糖尿病用的药物的用途
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
JP6367115B2 (ja) 2011-08-29 2018-08-01 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病患者の血糖コントロールに使用する組合せ医薬
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CN108383902A (zh) 2012-09-26 2018-08-10 印第安纳大学研究及科技有限公司 胰岛素类似物二聚体
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
IL102240A0 (en) * 1991-06-21 1993-01-14 Lilly Co Eli Insulin analogs

Also Published As

Publication number Publication date
EP0605983A2 (en) 1994-07-13
ZA939477B (en) 1995-06-19
AU5827994A (en) 1994-07-19
PL310007A1 (en) 1995-11-13
FI953001L (fi) 1995-06-16
EP0605983A3 (en) 1995-06-07
CA2151134A1 (en) 1994-07-07
WO1994014461A1 (en) 1994-07-07
BR9307687A (pt) 2002-02-19
CZ158895A3 (en) 1995-12-13
FI953001A7 (fi) 1995-06-16
HU9501762D0 (en) 1995-08-28
CN1094059A (zh) 1994-10-26
NO952336D0 (no) 1995-06-13
AU680462B2 (en) 1997-07-31
JPH08504820A (ja) 1996-05-28
HUT71583A (en) 1995-12-28
FI953001A0 (fi) 1995-06-16
MX9307991A (es) 1994-08-31

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