NO952635L - Syntetiske peptidderivater og salter derav - Google Patents

Syntetiske peptidderivater og salter derav

Info

Publication number
NO952635L
NO952635L NO952635A NO952635A NO952635L NO 952635 L NO952635 L NO 952635L NO 952635 A NO952635 A NO 952635A NO 952635 A NO952635 A NO 952635A NO 952635 L NO952635 L NO 952635L
Authority
NO
Norway
Prior art keywords
seo
peptide
peptide derivatives
sequence
ala
Prior art date
Application number
NO952635A
Other languages
English (en)
Other versions
NO952635D0 (no
Inventor
Takashi Kurita
Tomoaki Matsumoto
Reiko Kikuno
Yoko Hamamoto
Gerhard Breipohl
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of NO952635D0 publication Critical patent/NO952635D0/no
Publication of NO952635L publication Critical patent/NO952635L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Syntetiske peptidderivater representert ved formelen pl_Rl_P2 hvor P1 er et peptld som har en amlnosyresekvens i SEO ID NO: l ifølge sekvensllsten, eller analoger derav er beskrevet. P2 er et peptid som har en amlnosyresekvens l SEO ID NO: 2 ifølge sekvensllsten, eller analoger derav; R1 angir en linker med en egenskap som ikke interfererer med aktiviteten til hvert peptld P1 og P2 for å binde den N-terminale enden av peptidene P1 og P2. En farmasøytisk sammensetning for behandling av benrelaterte sykdommer omfattende nevnte peptid- derivater, eller et terapeutisk akseptabelt salt derav, eller en farmasøytisk akseptabel bærer. En fremgangsmåte for behandling av benrelaterte sykdommer l et pattedyr omfattende administrering av en effektiv mengde av nevnte peptidderivater, eller terapeutiske akseptable salter derav er også beskrevet. SEKVENSBESKRIVELSE: SEO ID NO: 1: Asp Phe Ser Asp Val Gly Trp Asn Asp Trp Ile Val Ala Pro Pro Gly 1 5 10 15 Tyr SEO ID NO: 2: Ala Ile Val Gin Thr Leu Val Asn Ser Val Asn Ser Lys Ile Pro Lys il 5 10 15 Ala R! omfatter: organiske grupper med karboksylgrupper ved begge ender.
NO952635A 1994-07-04 1995-07-03 Syntetiske peptidderivater og salter derav NO952635L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18420394 1994-07-04

Publications (2)

Publication Number Publication Date
NO952635D0 NO952635D0 (no) 1995-07-03
NO952635L true NO952635L (no) 1996-01-05

Family

ID=16149169

Family Applications (1)

Application Number Title Priority Date Filing Date
NO952635A NO952635L (no) 1994-07-04 1995-07-03 Syntetiske peptidderivater og salter derav

Country Status (8)

Country Link
US (1) US5908828A (no)
EP (1) EP0691349A3 (no)
KR (1) KR960004366A (no)
AU (1) AU695241B2 (no)
CA (1) CA2153109A1 (no)
FI (1) FI953269L (no)
HU (1) HUT72068A (no)
NO (1) NO952635L (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19548476A1 (de) * 1995-12-22 1997-06-26 Bioph Biotech Entw Pharm Gmbh Zielgerichtete Verbindungen mit knorpel- und/oder knocheninduzierender Aktivität
JP2000119192A (ja) 1998-10-09 2000-04-25 Aventis Pharma Ltd 骨誘導因子アンタゴニスト活性を有する成熟型蛋白質
DE10026713A1 (de) * 2000-05-30 2001-12-06 Walter Sebald Mutein einer Kette eines Proteins aus der Superfamilie des Wachstumsfaktors TGF-beta
GB2369973B (en) * 2000-12-06 2002-12-04 Open Business Exchange Ltd Communication Router
JP2009539767A (ja) * 2006-06-02 2009-11-19 ワイス 精製および治療方法のためのＴＧＦ−βスーパーファミリータンパク質およびペプチドの使用
US7754689B2 (en) 2006-06-02 2010-07-13 Wyeth Llc Finger-1 peptide analogs of the TGF-β superfamily
EP2347730A1 (en) * 2007-09-04 2011-07-27 Affinergy, Inc. Methods and compositions for delivery of growth factor to fibrous connective tissue
US9040046B2 (en) 2011-01-31 2015-05-26 Kai Xu Sodium pump antibody agonists and methods of treating heart disease using the same
KR20240142627A (ko) * 2023-03-21 2024-10-02 주식회사 아모라이프사이언스 골세포 분화용 세포배양기재 및 이의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284756A (en) * 1988-10-11 1994-02-08 Lynn Grinna Heterodimeric osteogenic factor
KR100259827B1 (ko) * 1991-11-04 2000-06-15 브루스 엠. 에이센, 토마스 제이 데스로저 재조합 골형태 형성 단백질 헤테로다이머, 그 조성물 및 사용방법
EP0626451A3 (en) * 1993-05-27 1997-11-05 Takeda Chemical Industries, Ltd. Heterodimers of a TGF-beta superfamily

Also Published As

Publication number Publication date
FI953269A0 (fi) 1995-06-30
FI953269A7 (fi) 1996-01-05
KR960004366A (ko) 1996-02-23
AU2337595A (en) 1996-01-18
HU9502018D0 (en) 1995-09-28
AU695241B2 (en) 1998-08-13
US5908828A (en) 1999-06-01
HUT72068A (en) 1996-03-28
EP0691349A3 (en) 1997-09-10
EP0691349A2 (en) 1996-01-10
CA2153109A1 (en) 1996-01-05
FI953269L (fi) 1996-01-05
NO952635D0 (no) 1995-07-03

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Legal Events

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