NO953220L - Mesotetrafenylporfyrinkompleksforbindelser, fremgangsmåter for deres fremstilling og midler som inneholder dem - Google Patents

Mesotetrafenylporfyrinkompleksforbindelser, fremgangsmåter for deres fremstilling og midler som inneholder dem

Info

Publication number
NO953220L
NO953220L NO953220A NO953220A NO953220L NO 953220 L NO953220 L NO 953220L NO 953220 A NO953220 A NO 953220A NO 953220 A NO953220 A NO 953220A NO 953220 L NO953220 L NO 953220L
Authority
NO
Norway
Prior art keywords
pct
complex compounds
mesotetrafenyl
preparation
methods
Prior art date
Application number
NO953220A
Other languages
English (en)
Other versions
NO953220D0 (no
Inventor
Franz Karl Maier
Wolfgang Ebert
Mary Lee-Vaupel
Heinz Gries
Jurgen Conrad
Original Assignee
Diagnostikforschung Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostikforschung Inst filed Critical Diagnostikforschung Inst
Publication of NO953220D0 publication Critical patent/NO953220D0/no
Publication of NO953220L publication Critical patent/NO953220L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Porfyrinkompleksforbindelser be- stående av en mesotetrafenylporfyrin- llgand med den generelle formel (I) (I) hvor R1, R2 og R3 har forskjellige be- tydninger, og et ion av et grunnstoff med atomnumrene 21-32, 38, 39, 42-51 eller 58-83, samt eventuelt ett eller flere fysiologisk akseptable kation(er) av uorganiske og/eller organiske baser, aminosyrer eller aminosyreamider, er verdifulle diagnostika.
NO953220A 1993-02-17 1995-08-16 Mesotetrafenylporfyrinkompleksforbindelser, fremgangsmåter for deres fremstilling og midler som inneholder dem NO953220L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4305523A DE4305523A1 (de) 1993-02-17 1993-02-17 Meso-Tetraphenylporphyrin-Komplexverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
PCT/DE1994/000159 WO1994019352A1 (de) 1993-02-17 1994-02-11 Meso-tetraphenylporphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
NO953220D0 NO953220D0 (no) 1995-08-16
NO953220L true NO953220L (no) 1995-10-16

Family

ID=6481125

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953220A NO953220L (no) 1993-02-17 1995-08-16 Mesotetrafenylporfyrinkompleksforbindelser, fremgangsmåter for deres fremstilling og midler som inneholder dem

Country Status (11)

Country Link
US (1) US5674467A (no)
EP (1) EP0684948B1 (no)
JP (1) JPH08506819A (no)
AT (1) ATE159526T1 (no)
CA (1) CA2156158A1 (no)
DE (2) DE4305523A1 (no)
DK (1) DK0684948T3 (no)
ES (1) ES2110735T3 (no)
GR (1) GR3025770T3 (no)
NO (1) NO953220L (no)
WO (1) WO1994019352A1 (no)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
EP0758907A1 (en) * 1994-05-11 1997-02-26 Schering Aktiengesellschaft The use of porphyrin-complex or expanded porphyrin-complex compounds as localization diagnosticum for infarction or necrosis
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
US5883246A (en) * 1996-03-07 1999-03-16 Qlt Phototherapeutics, Inc. Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds
US6444194B1 (en) 1997-02-14 2002-09-03 Miravant Pharmaceuticals, Inc. Indium photosensitizers for PDT
WO1999023097A1 (en) 1997-11-03 1999-05-14 Duke University Substituted porphyrins
DE19824653A1 (de) * 1998-02-25 1999-08-26 Schering Ag Nekrose-affine Verbindungen und ihre Verwendung zur Herstellung von Präparaten zur Pharmakotherapie
ES2257858T3 (es) * 1998-04-24 2006-08-01 Duke University Porfirinas sustituidas.
EP1107971B1 (en) 1998-08-28 2004-11-24 Destiny Pharma Limited Porphyrin derivatives, their use in photodynamic therapy and medical devices containing them
ATE312103T1 (de) 1999-01-25 2005-12-15 Nat Jewish Med & Res Center Substituierte porphyrine und deren therapeutische verwendungen
US6433162B1 (en) 1999-03-05 2002-08-13 Emory University Method for synthesizing porphyrin compounds
US6376664B1 (en) * 1999-03-17 2002-04-23 The Ohio State University Cyclic bis-benzimidazole ligands and metal complexes thereof
US6403788B1 (en) 2000-07-11 2002-06-11 Eukarion, Inc. Non-genotoxic metalloporphyrins as synthetic catalytic scavengers of reactive oxygen species
JP4678661B2 (ja) * 2000-12-04 2011-04-27 日本化薬株式会社 新規なテトラキスアミノフェニル(ジ)フェニレンジアミン骨格を有する化合物
DE60233317D1 (de) * 2001-01-19 2009-09-24 Nat Jewish Med & Res Center Medikament zum schutz in der radiotherapie
US7048907B2 (en) * 2001-02-05 2006-05-23 Biophysics Assay Laboratory, Inc. Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products
EP1439842A4 (en) * 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
US6566517B2 (en) 2001-06-06 2003-05-20 Brookhaven Science Associates, Llc Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy
IL147898A (en) * 2002-01-30 2007-05-15 Yuval Golan A method of treating cancer based on the Ugar effect
US7485721B2 (en) * 2002-06-07 2009-02-03 Duke University Substituted porphyrins
AU2003299346A1 (en) * 2002-12-20 2004-08-10 Centre National De La Recherche Scientifique Porphyrin derivatives, methods for obtaining same, and use thereof in radioimmunotherapy
FR2849035B1 (fr) * 2002-12-20 2005-05-20 Derives des porphyrines, leurs procedes d'obtention, et leurs utilisations en radioimmunotherapie
GB2397067B (en) 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
FR2867473B1 (fr) 2004-03-12 2006-06-23 Guerbet Sa Compose de porphyrines et utilisation a haut champ en irm
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US6989443B2 (en) * 2004-06-28 2006-01-24 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
IL181126A0 (en) * 2006-11-01 2007-07-04 S B Biotechnologies Ltd Preparation of gold-containing nano-liposome particles and their use in medical therapy
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
CN102105146A (zh) 2008-05-23 2011-06-22 国立犹太保健医院 用于治疗与暴露于烷化物质有关的损伤的方法
GB0914287D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Compositions
GB0914286D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Method
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
CN102408430B (zh) * 2011-09-07 2013-11-06 沅江华龙催化科技有限公司 取代四苯基双铁卟啉的合成工艺与专用设备
CN113754672B (zh) * 2021-10-27 2024-05-03 上海先辉医药科技有限公司 一类新型四吡咯化合物及其应用
CN116425765B (zh) * 2023-04-13 2025-07-01 安徽元梦生物基材料科技有限公司 金属卟啉-乳酸化合物的制备及阻燃抗熔滴pla材料

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3809671A1 (de) * 1988-03-18 1989-09-28 Schering Ag Porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5284647A (en) * 1988-03-18 1994-02-08 Schering Aktiengesellschaft Mesotetraphenylporphyrin complex compounds, process for their production and pharmaceutical agents containing them
US5262532A (en) * 1991-07-22 1993-11-16 E.R. Squibb & Sons, Inc. Paramagnetic metalloporphyrins as contrast agents for magnetic resonance imaging

Also Published As

Publication number Publication date
ATE159526T1 (de) 1997-11-15
DE4305523A1 (de) 1994-08-18
DE59404433D1 (de) 1997-11-27
DK0684948T3 (da) 1998-07-20
JPH08506819A (ja) 1996-07-23
EP0684948A1 (de) 1995-12-06
WO1994019352A1 (de) 1994-09-01
CA2156158A1 (en) 1994-09-01
NO953220D0 (no) 1995-08-16
GR3025770T3 (en) 1998-03-31
US5674467A (en) 1997-10-07
ES2110735T3 (es) 1998-02-16
EP0684948B1 (de) 1997-10-22

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