NO960247L - Transformant systems of Candida utilis and the expression of heterologous genes thereby - Google Patents

Transformant systems of Candida utilis and the expression of heterologous genes thereby

Info

Publication number
NO960247L
NO960247L NO960247A NO960247A NO960247L NO 960247 L NO960247 L NO 960247L NO 960247 A NO960247 A NO 960247A NO 960247 A NO960247 A NO 960247A NO 960247 L NO960247 L NO 960247L
Authority
NO
Norway
Prior art keywords
transformant
expression
systems
heterologous genes
candida utilis
Prior art date
Application number
NO960247A
Other languages
Norwegian (no)
Other versions
NO960247D0 (en
Inventor
Keiji Kondo
Susumu Kajiwara
Norihiko Misawa
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Publication of NO960247D0 publication Critical patent/NO960247D0/en
Publication of NO960247L publication Critical patent/NO960247L/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/40Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

A GAP-gene promoter sequence, a GAP gene terminator sequence and a gene expression unit comprising same.
NO960247A 1994-05-25 1996-01-22 Transformant systems of Candida utilis and the expression of heterologous genes thereby NO960247L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP13501594 1994-05-25
JP28582394 1994-10-26
JP7129287A JPH08173170A (en) 1994-05-25 1995-04-28 Transformation system of Candida utilis yeast and expression of heterologous gene by it
PCT/JP1995/001005 WO1995032289A1 (en) 1994-05-25 1995-05-25 Transformant line of candida utilis yeast and expression of heterogene therewith

Publications (2)

Publication Number Publication Date
NO960247D0 NO960247D0 (en) 1996-01-22
NO960247L true NO960247L (en) 1996-03-22

Family

ID=27315910

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960247A NO960247L (en) 1994-05-25 1996-01-22 Transformant systems of Candida utilis and the expression of heterologous genes thereby

Country Status (11)

Country Link
US (1) US5849524A (en)
EP (2) EP0717107B1 (en)
JP (4) JPH08173170A (en)
KR (2) KR100263962B1 (en)
AT (1) ATE347598T1 (en)
AU (1) AU699864B2 (en)
CA (1) CA2168037C (en)
DE (1) DE69535326T2 (en)
FI (1) FI121013B (en)
NO (1) NO960247L (en)
WO (1) WO1995032289A1 (en)

Families Citing this family (33)

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US6642021B2 (en) 1996-03-29 2003-11-04 University Of Maryland Methods of producing carotenoids by the expression of plant ε-cyclase genes
DE69739107D1 (en) 1996-08-23 2008-12-24 Kirin Brewery HEFEVEKTOREN AND METHOD FOR THE USE OF THE PRODUCTION OF PROTEINS.
CU22722A1 (en) * 1996-10-03 2002-02-28 Ct Ingenieria Genetica Biotech TRANSFORMATION SYSTEM FOR THE EXPRESSION OF HETEROLOGICAL GENES IN CANDIDA UTILIS YEAST
DE19736343B4 (en) * 1997-08-21 2006-02-09 Forschungszentrum Jülich GmbH Method for increasing gene expression of sucrose synthase
WO1999057279A1 (en) * 1998-05-07 1999-11-11 Doosan Corporation Plasmid for gene expression in pichia ciferrii and transformation method using the same
JP2000342263A (en) * 1999-06-02 2000-12-12 Japan Energy Corp Hygromycin resistance gene and transformed Candida yeast
DE19963690A1 (en) * 1999-11-23 2001-06-13 Rhein Biotech Proz & Prod Gmbh Vectors and methods for producing recombinant proteins in fungi
CN1301747A (en) * 1999-12-27 2001-07-04 上海博德基因开发有限公司 New polypeptide-ribosome S19e protein and polynucleotide coding such polypeptide
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
JP2002325573A (en) * 2001-04-27 2002-11-12 Japan Science & Technology Corp vector
US6645739B2 (en) * 2001-07-26 2003-11-11 Phoenix Pharmacologies, Inc. Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
CA2474152A1 (en) * 2001-11-23 2003-06-19 Natureworks Llc Methods and materials for the production of organic products in cells of candida species
ES2529254T3 (en) * 2002-05-30 2015-02-18 Cargill Inc. Fermentation process using specific oxygen incorporation rates as a process control
JP4587750B2 (en) * 2004-09-13 2010-11-24 株式会社興人 Candida utilis-derived gene encoding transcriptional activation protein
JP4671394B2 (en) * 2004-09-13 2011-04-13 株式会社興人 Promoter DNA from Candida utilis
JP4563228B2 (en) * 2004-09-13 2010-10-13 株式会社興人 ARS gene from Candida utilis
CN103589650A (en) 2005-03-18 2014-02-19 米克罗比亚公司 Production of carotenoids in oleaginous yeast and fungi
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
WO2008041385A1 (en) 2006-09-29 2008-04-10 National University Corporation NARA Institute of Science and Technology Novel alkane polyol dehydrogenase
US20090277974A1 (en) * 2008-05-06 2009-11-12 Samino Citrawireja Lawn And Garden Sprinkler Housing
EP2330190A1 (en) 2008-09-01 2011-06-08 Daicel Chemical Industries, Ltd. Process for production of optically active amine derivative
WO2010024445A1 (en) 2008-09-01 2010-03-04 ダイセル化学工業株式会社 Process for production of optically active amine derivative
WO2010095750A1 (en) * 2009-02-23 2010-08-26 キリンホールディングス株式会社 Manufacturing method for substances from candida utilis that can use xylose as carbon source
US8158391B2 (en) 2009-05-06 2012-04-17 Dna Twopointo, Inc. Production of an α-carboxyl-ω-hydroxy fatty acid using a genetically modified Candida strain
US8597923B2 (en) * 2009-05-06 2013-12-03 SyntheZyme, LLC Oxidation of compounds using genetically modified Candida
JP5787360B2 (en) 2009-10-30 2015-09-30 株式会社ダイセル Genetically modified microorganisms provided with 1,3-butanediol production function and use thereof
CN103348014B (en) 2010-10-05 2020-11-03 味之素株式会社 Gamma-Glu-Abu-containing yeast and yeast extract, and method for producing same
EP3020801A4 (en) 2013-07-12 2017-01-18 Ajinomoto Co., Inc. YEAST WITH HIGH CONTENT OF Abu, upsilon-Glu-Abu, AND/OR UPSILON-Glu-Abu-Gly
CN108779480A (en) 2015-08-24 2018-11-09 味之素株式会社 The method for producing sphingosine and sphingolipid
CN108473968A (en) 2015-08-24 2018-08-31 味之素株式会社 The method for producing phytosphingosine or dihydrosphingosine
CN112575013B (en) * 2020-12-24 2022-05-17 广东省微生物研究所(广东省微生物分析检测中心) Application of gene GNATB as screening marker gene in resistance screening
WO2022158535A1 (en) 2021-01-20 2022-07-28 Ajinomoto Co., Inc. Method for producing phytosphingosine or phytoceramide
JP2024505831A (en) 2021-01-20 2024-02-08 味の素株式会社 Method for producing phytosphingosine or phytoceramide

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CA1341302C (en) * 1983-02-22 2001-10-09 Rae Lyn Burke Yeast expression systems with vectors having gapdh or pyk promoters and synthesis of foreign protein
JPS59162884A (en) * 1983-03-09 1984-09-13 Kohjin Co Ltd Novel hybrid plasmid and microorganism containing the same
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
JPS60210815A (en) * 1984-04-04 1985-10-23 Hitachi Ltd transformer core
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
JPS6442673A (en) 1987-08-11 1989-02-14 Seiko Epson Corp Printer
JP3036002B2 (en) * 1990-07-06 2000-04-24 東洋紡績株式会社 DNA fragment containing ADE1 gene derived from Candida utilis
FR2679253B1 (en) * 1991-07-15 1994-09-02 Pasteur Institut CYCLOHEXIMIDE RESISTANCE PROTEINS. USE AS A SELECTION MARKER FOR EXAMPLE TO CONTROL THE TRANSFER OF NUCLEIC ACIDS.
JP3113435B2 (en) * 1992-02-28 2000-11-27 サントリー株式会社 Novel vector having promoter inducible by addition of methanol and / or glycerol
JP2984143B2 (en) * 1992-05-15 1999-11-29 キッコーマン株式会社 Novel uricase gene, novel recombinant DNA and method for producing uricase
JPH0614865A (en) 1992-07-02 1994-01-25 Asahi Optical Co Ltd End of endoscope
DE4244915C2 (en) * 1992-08-14 1998-12-03 Widmar Prof Dr Tanner Fungal cells contg. mutated DPM2 mannosyl transferase gene

Also Published As

Publication number Publication date
WO1995032289A1 (en) 1995-11-30
EP0717107A4 (en) 2002-05-22
US5849524A (en) 1998-12-15
FI121013B (en) 2010-06-15
JP2003144185A (en) 2003-05-20
JP3385027B2 (en) 2003-03-10
EP1792993A1 (en) 2007-06-06
EP0717107A1 (en) 1996-06-19
JP2003174879A (en) 2003-06-24
JP4623925B2 (en) 2011-02-02
DE69535326D1 (en) 2007-01-18
FI960331A0 (en) 1996-01-24
KR100320905B1 (en) 2002-01-23
AU2537795A (en) 1995-12-18
DE69535326T2 (en) 2007-06-21
KR100263962B1 (en) 2000-08-16
ATE347598T1 (en) 2006-12-15
NO960247D0 (en) 1996-01-22
EP0717107B1 (en) 2006-12-06
CA2168037A1 (en) 1995-11-30
FI960331L (en) 1996-03-20
JPH08173170A (en) 1996-07-09
JP4017966B2 (en) 2007-12-05
CA2168037C (en) 2003-07-01
AU699864B2 (en) 1998-12-17

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