NO961161L - Metallkomplekser med ladede linkere - Google Patents

Metallkomplekser med ladede linkere

Info

Publication number
NO961161L
NO961161L NO961161A NO961161A NO961161L NO 961161 L NO961161 L NO 961161L NO 961161 A NO961161 A NO 961161A NO 961161 A NO961161 A NO 961161A NO 961161 L NO961161 L NO 961161L
Authority
NO
Norway
Prior art keywords
metal complexes
charged linkers
linkers
charged
immunoassay
Prior art date
Application number
NO961161A
Other languages
English (en)
Other versions
NO961161D0 (no
Inventor
Hans-Peter Josel
Eva Hoss
Beatus Ofenloch-Hahnle
Christoph Seidel
Barbara Upheimer
Ursula-Henrike Wienhues
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4430998A external-priority patent/DE4430998A1/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO961161L publication Critical patent/NO961161L/no
Publication of NO961161D0 publication Critical patent/NO961161D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds
    • C07F15/0053—Ruthenium compounds without a metal-carbon linkage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in epitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Electroluminescent Light Sources (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)

Abstract

Det blir beskrevet nye metallkomplekser med ladede linkere og deres anvendelse som luminiserende markeringsgrupper i immunoanalyse.
NO961161A 1994-07-25 1996-03-21 Metallkomplekser med ladede linkere NO961161D0 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE4426276 1994-07-25
DE4430998A DE4430998A1 (de) 1994-07-25 1994-08-31 Metallchelat-markierte Peptide
DE4439345A DE4439345A1 (de) 1994-07-25 1994-11-04 Oligomere Trägermoleküle mit definiert eingebauten Markierungsgruppen und Haptenen
DE4439347A DE4439347A1 (de) 1994-07-25 1994-11-04 Metallkomplexe mit geladenem Linker
PCT/EP1995/002920 WO1996003409A1 (de) 1994-07-25 1995-07-24 Metallkomplexe mit geladenem linker

Publications (2)

Publication Number Publication Date
NO961161L true NO961161L (no) 1996-03-21
NO961161D0 NO961161D0 (no) 1996-03-21

Family

ID=27436023

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961161A NO961161D0 (no) 1994-07-25 1996-03-21 Metallkomplekser med ladede linkere

Country Status (13)

Country Link
US (1) US5958783A (no)
EP (1) EP0720614B1 (no)
JP (1) JP2771900B2 (no)
CN (1) CN1046531C (no)
AT (1) ATE193294T1 (no)
AU (1) AU690315B2 (no)
CA (1) CA2172145C (no)
DE (1) DE59508391D1 (no)
ES (1) ES2148540T3 (no)
FI (1) FI961349A0 (no)
NO (1) NO961161D0 (no)
NZ (1) NZ291154A (no)
WO (1) WO1996003409A1 (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998029736A1 (en) * 1996-12-31 1998-07-09 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
DE19811582A1 (de) 1998-03-17 1999-09-23 Roche Diagnostics Gmbh Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen
DE19828441A1 (de) * 1998-06-25 1999-12-30 Roche Diagnostics Gmbh Verwendung derivatisierter Reagenzien in Chemilumineszenz- und Elektrochemilumineszenz-Nachweisverfahren
DE19828466A1 (de) 1998-06-26 1999-12-30 Roche Diagnostics Gmbh Entstörung von Immunoassays durch Substanzen, die aus den Framework-Regionen von Antikörpern abgeleitet sind
US20050112607A1 (en) * 1999-01-23 2005-05-26 Bamdad Cynthia C. Rapid and sensitive detection of protein aggregation
US6300143B1 (en) * 1999-03-01 2001-10-09 Idec Pharmaceuticals Corporation Electrochemiluminescent assays for eukaryotic cells
US7897404B2 (en) * 2000-09-29 2011-03-01 Roche Diagnostics Operations, Inc. Conjugates of defined stoichiometry
DE10048417A1 (de) * 2000-09-29 2002-04-11 Roche Diagnostics Gmbh Verbindungen mit verzweigtem Linker
EP1245956A1 (en) * 2001-03-29 2002-10-02 Roche Diagnostics GmbH Conjugates of defined stoichiometry
AU2002230524A1 (en) 2000-11-16 2002-05-27 California Institute Of Technology Apparatus and methods for conducting assays and high throughput screening
US7135296B2 (en) 2000-12-28 2006-11-14 Mds Inc. Elemental analysis of tagged biologically active materials
US7700295B2 (en) * 2000-12-28 2010-04-20 Mds Sciex Elemental analysis of tagged biologically active materials
US6808939B2 (en) 2001-06-29 2004-10-26 Igen International, Inc. ECL labels having improved non-specific binding properties, methods of using and kits containing the same
US7763439B2 (en) * 2001-07-02 2010-07-27 Arctic Diagnostics Oy Two-photon absorbing dipyrrometheneboron difluoride dyes and their applications
DE60214709T2 (de) * 2001-07-02 2007-09-13 Arctic Diagnostics Oy Verfahren zur Erhöhung der Hydrophilie von Fluoreszenzmarker-Verbindungen
US6989273B2 (en) * 2002-02-08 2006-01-24 Canon Kabushiki Kaisha Light emissive iridium (III) complexes
DE10227599B4 (de) * 2002-06-20 2005-04-28 Proteome Factory Ag Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe
DE10239098A1 (de) * 2002-08-26 2004-03-11 Roche Diagnostics Gmbh Erzeugung von Chemilumineszenz durch Wasserstoff
TW200508606A (en) * 2003-03-07 2005-03-01 Nard Kenkyusho Kk Method of finding molecular weight of phosphoric acid monoester compound, and additive for mass spectrometric measurement
ES2309785T3 (es) 2004-08-13 2008-12-16 F. Hoffmann-La Roche Ag Modificacion c-terminal de polipeptidos.
DE102005032332A1 (de) * 2005-07-08 2007-01-11 Merck Patent Gmbh Metallkomplexe
US8101368B2 (en) * 2006-02-13 2012-01-24 Dvs Sciences Inc. Quantitation of cellular DNA and cell numbers using element labeling
CN101395473B (zh) * 2006-03-20 2012-09-19 阿莱瑞士股份有限公司 利用水溶性轭合物的电化学检测方法
CA2649154A1 (en) * 2006-04-14 2007-10-25 Proteome Factory Ag Method and reagent for the specific identification and quantification of one or more proteins in a sample using inductively coupled plasma-mass spectrometry
GB0711849D0 (en) 2007-06-19 2007-07-25 Oxford Biosensors Ltd Redox Mediators
DE102007032799B4 (de) 2007-07-11 2018-08-23 Friedrich-Schiller-Universität Jena Zuckerhaltige Metallkomplexe und deren Verwendung
US8637194B2 (en) 2008-09-02 2014-01-28 Bio-Nano Power, Llc Bio-nano power cells and their uses
CN101747381B (zh) * 2008-12-19 2013-09-11 苏州纳凯科技有限公司 用作生物标记物的环金属铱配位化合物
EP2512372B1 (en) 2009-12-18 2020-04-29 AMO Groningen B.V. Ophthalmic lens with angular varying phase delay
WO2012055815A1 (en) 2010-10-25 2012-05-03 Roche Diagnostics Gmbh Use of signal enhancing compounds in electrochemiluminescence detection
US10406227B2 (en) 2012-12-19 2019-09-10 California Institute Of Technology Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using same
WO2017031380A1 (en) * 2015-08-19 2017-02-23 University Of Southern California Photoactivated molecules for light-induced modulation of the activity of electrically excitable cells and methods of using
ES2974284T3 (es) 2016-03-11 2024-06-26 Roche Diagnostics Gmbh Aminas de cadena ramificada en la detección de electroquimioluminiscencia
CN107759799B (zh) * 2017-09-21 2020-10-23 中山大学 一种三联吡啶钌-赖氨酸聚合物固相合成方法
CA3169298A1 (en) * 2020-02-27 2021-09-02 The Trustees Of Princeton University Intercellular and intracellular proximity-based labeling compositions and systems

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075447A (en) * 1984-09-17 1991-12-24 Hoffmann-La Roche Inc. Ruthenium complexes useful as carriers for immunologically active materials
DK365785A (da) * 1984-09-17 1986-03-18 Hoffmann La Roche Metalcomplexer
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection

Also Published As

Publication number Publication date
WO1996003409A1 (de) 1996-02-08
CN1046531C (zh) 1999-11-17
FI961349L (fi) 1996-03-25
FI961349A7 (fi) 1996-03-25
CA2172145A1 (en) 1996-02-08
EP0720614B1 (de) 2000-05-24
CA2172145C (en) 2010-09-21
DE59508391D1 (de) 2000-06-29
EP0720614A1 (de) 1996-07-10
ES2148540T3 (es) 2000-10-16
JP2771900B2 (ja) 1998-07-02
ATE193294T1 (de) 2000-06-15
FI961349A0 (fi) 1996-03-25
US5958783A (en) 1999-09-28
NO961161D0 (no) 1996-03-21
CN1134154A (zh) 1996-10-23
NZ291154A (en) 1997-11-24
AU690315B2 (en) 1998-04-23
AU3220595A (en) 1996-02-22
JPH08509995A (ja) 1996-10-22

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application