NO961622L - Inhibition of photo-cleavage of 3-substituted 2-oxindoles - Google Patents

Inhibition of photo-cleavage of 3-substituted 2-oxindoles

Info

Publication number
NO961622L
NO961622L NO961622A NO961622A NO961622L NO 961622 L NO961622 L NO 961622L NO 961622 A NO961622 A NO 961622A NO 961622 A NO961622 A NO 961622A NO 961622 L NO961622 L NO 961622L
Authority
NO
Norway
Prior art keywords
substituted
oxindoles
cleavage
inhibition
photo
Prior art date
Application number
NO961622A
Other languages
Norwegian (no)
Other versions
NO961622D0 (en
Inventor
Willard C Newlin Jr
Sharon M Laughlin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO961622D0 publication Critical patent/NO961622D0/en
Publication of NO961622L publication Critical patent/NO961622L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4883Capsule finishing, e.g. dyeing, aromatising, polishing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Polymerisation Methods In General (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Oppfinnelsen angår beskyttelsen av visse 3-substituerte- 2-oksindol-l-karboksamider med formel og deres farmasøytisk akseptable basesalter, hvor X er H, Cl eller F; Y er H eller Cl; og R er benzyl eller tienyl, hver eventuelt substituert med Cl eller F, mot en spaltning i nærvær av lys.The invention relates to the protection of certain 3-substituted-2-oxindole-1-carboxamides of formula and their pharmaceutically acceptable base salts, wherein X is H, Cl or F; Y is H or Cl; and R is benzyl or thienyl, each optionally substituted with Cl or F, against a decomposition in the presence of light.

NO961622A 1995-04-24 1996-04-23 Inhibition of photo-cleavage of 3-substituted 2-oxindoles NO961622L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB1995/000287 WO1996033701A1 (en) 1995-04-24 1995-04-24 Inhibiting photodecomposition of 3-substituted-2-oxindoles

Publications (2)

Publication Number Publication Date
NO961622D0 NO961622D0 (en) 1996-04-23
NO961622L true NO961622L (en) 1996-10-25

Family

ID=36997502

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961622A NO961622L (en) 1995-04-24 1996-04-23 Inhibition of photo-cleavage of 3-substituted 2-oxindoles

Country Status (30)

Country Link
EP (1) EP0827399A1 (en)
JP (1) JPH10506635A (en)
KR (1) KR100189585B1 (en)
CN (1) CN1053667C (en)
AP (1) AP607A (en)
AR (1) AR002728A1 (en)
AU (1) AU692378B2 (en)
BG (1) BG100531A (en)
BR (1) BR9602024A (en)
CO (1) CO4700418A1 (en)
FI (1) FI973988A0 (en)
HR (1) HRP960194A2 (en)
HU (1) HU216544B (en)
IL (1) IL117969A0 (en)
IS (1) IS4339A (en)
MA (1) MA23848A1 (en)
NO (1) NO961622L (en)
NZ (1) NZ286432A (en)
OA (1) OA10286A (en)
PE (1) PE34397A1 (en)
RO (1) RO113305B1 (en)
RU (1) RU2109510C1 (en)
SG (1) SG64924A1 (en)
SI (1) SI9600133A (en)
SK (1) SK51296A3 (en)
TR (1) TR199600300A2 (en)
UA (1) UA42739C2 (en)
WO (1) WO1996033701A1 (en)
YU (1) YU25096A (en)
ZA (1) ZA963210B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111526730B (en) 2017-12-29 2024-02-23 卡夫食品集团品牌有限责任公司 Improved oxidative stability of oil-in-water emulsions using natural stabilizers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3136282A1 (en) * 1981-09-12 1983-03-24 Hoechst Ag "METHOD FOR STABILIZING PHOTO-UNSTABLE MEDICINAL PRODUCTS AND STABILIZED MEDICAL PREPARATIONS"
HUT59592A (en) * 1990-07-20 1992-06-29 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of solid medical products
TW438798B (en) * 1992-10-07 2001-06-07 Pfizer 3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions

Also Published As

Publication number Publication date
HUP9601057A2 (en) 1997-04-28
AP607A (en) 1997-08-27
MA23848A1 (en) 1996-12-31
AU692378B2 (en) 1998-06-04
UA42739C2 (en) 2001-11-15
FI973988L (en) 1997-10-17
KR100189585B1 (en) 1999-06-01
RO113305B1 (en) 1998-06-30
HUP9601057A3 (en) 1997-05-28
CN1139110A (en) 1997-01-01
SK51296A3 (en) 1997-04-09
IS4339A (en) 1996-10-25
BR9602024A (en) 1998-10-06
CO4700418A1 (en) 1998-12-29
HRP960194A2 (en) 1998-02-28
AU5085196A (en) 1996-11-07
TR199600300A2 (en) 1996-11-21
CN1053667C (en) 2000-06-21
AR002728A1 (en) 1998-04-29
ZA963210B (en) 1997-10-23
EP0827399A1 (en) 1998-03-11
AP9600787A0 (en) 1996-04-30
KR960037656A (en) 1996-11-19
RU2109510C1 (en) 1998-04-27
FI973988A7 (en) 1997-10-17
HU216544B (en) 1999-07-28
HU9601057D0 (en) 1996-06-28
JPH10506635A (en) 1998-06-30
YU25096A (en) 1998-08-14
SG64924A1 (en) 1999-05-25
NO961622D0 (en) 1996-04-23
PE34397A1 (en) 1997-09-29
SI9600133A (en) 1996-10-31
FI973988A0 (en) 1997-10-17
NZ286432A (en) 1998-05-27
IL117969A0 (en) 1996-08-04
OA10286A (en) 1997-09-19
WO1996033701A1 (en) 1996-10-31
BG100531A (en) 1997-06-30

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