NO963029L - Use of IL-10 to stimulate cytological activity of single-core peripheral blood cells - Google Patents

Use of IL-10 to stimulate cytological activity of single-core peripheral blood cells

Info

Publication number
NO963029L
NO963029L NO963029A NO963029A NO963029L NO 963029 L NO963029 L NO 963029L NO 963029 A NO963029 A NO 963029A NO 963029 A NO963029 A NO 963029A NO 963029 L NO963029 L NO 963029L
Authority
NO
Norway
Prior art keywords
peripheral blood
stimulate
blood cells
core peripheral
cytological activity
Prior art date
Application number
NO963029A
Other languages
Norwegian (no)
Other versions
NO963029D0 (en
Inventor
Martin A Schwarz
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO963029D0 publication Critical patent/NO963029D0/en
Publication of NO963029L publication Critical patent/NO963029L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Denne oppfinnelsen vedrører anvendelse av IL-10, alene eller i kom- binasjon med IL-2 og/eller a-lFN, til å behandle neoplasmasykdommer ved å sti- mulere cytolytisk aktivitet av mono- nukleære celler fra perifert blod.This invention relates to the use of IL-10, alone or in combination with IL-2 and / or α-IFN, to treat neoplasmic diseases by stimulating cytolytic activity of peripheral blood mononuclear cells.

NO963029A 1994-01-20 1996-07-19 Use of IL-10 to stimulate cytological activity of single-core peripheral blood cells NO963029L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN94194863A CN1142186A (en) 1994-01-20 1994-01-20 Cytolytic activity of peripheral blood mononuclear cells activated by interleukin-10
PCT/IB1994/000008 WO1995019780A1 (en) 1994-01-20 1994-01-20 Use of il-10 to stimulate peripheral blood mononuclear cell cytolytic activity

Publications (2)

Publication Number Publication Date
NO963029D0 NO963029D0 (en) 1996-07-19
NO963029L true NO963029L (en) 1996-09-19

Family

ID=37708148

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963029A NO963029L (en) 1994-01-20 1996-07-19 Use of IL-10 to stimulate cytological activity of single-core peripheral blood cells

Country Status (10)

Country Link
EP (1) EP0740552A1 (en)
JP (1) JPH09508116A (en)
CN (1) CN1142186A (en)
AU (1) AU707019B2 (en)
FI (1) FI962813A0 (en)
NO (1) NO963029L (en)
NZ (1) NZ259584A (en)
PL (1) PL175343B1 (en)
SK (1) SK91696A3 (en)
WO (1) WO1995019780A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000037096A2 (en) * 1998-12-22 2000-06-29 Schering Corporation Treatment of hepatitis c virus infections with interleukin-10
EP2295450B1 (en) 2000-09-29 2015-01-28 Merck Sharp & Dohme Corp. Pegylated interleukin-10
RU2322452C2 (en) * 2006-03-27 2008-04-20 Михаил Николаевич Смирнов Immunomodulating composition
EP2066336B1 (en) 2006-09-28 2012-09-19 Merck Sharp & Dohme Corp. Use of pegylated il-10 to treat cancer
US20110044939A1 (en) * 2007-06-27 2011-02-24 Joslin Diabetes Center, Inc. Regulatory t cells in adipose tissue
ES2655364T3 (en) 2008-12-17 2018-02-19 Merck Sharp & Dohme Corp. Production of mono- and dipegilated IL-10 and its uses
MX2015014438A (en) 2013-04-18 2016-05-18 Armo Biosciences Inc Methods of using interleukin-10 for treating diseases and disorders.
EP3010527B1 (en) 2013-06-17 2018-08-08 Armo Biosciences, Inc. Method for assessing protein identity and stability
CN105658232A (en) 2013-08-30 2016-06-08 阿尔莫生物科技股份有限公司 Methods of using interleukin-10 for treating diseases and disorders
CN120242030A (en) 2013-11-11 2025-07-04 阿尔莫生物科技股份有限公司 Methods of using interleukin-10 to treat diseases and conditions
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
WO2016060996A2 (en) 2014-10-14 2016-04-21 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
AU2015336101A1 (en) 2014-10-22 2017-04-20 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US20160361415A1 (en) 2015-05-28 2016-12-15 Armo Biosciences, Inc. Methods of Using Interleukin-10 for Treating Diseases and Disorders
KR20180038553A (en) 2015-08-25 2018-04-16 아르모 바이오사이언시스 인코포레이티드 Methods for using interleukin-10 to treat diseases and disorders
WO2023072863A1 (en) * 2021-10-25 2023-05-04 Ellennbe Gmbh Pharmaceutical composition and kit comprising an immunomodulatory substance for treating diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE116550T1 (en) * 1991-01-16 1995-01-15 Schering Corp TREATMENT OF NEOPLASTIC DISEASES WITH INTERLEUKIN-10.
ES2074879T3 (en) * 1991-01-16 1995-09-16 Schering Corp USE OF INTERLEUKIN-10 IN ADOPTIVE CANCER IMMUNOTHERAPY.
US5055045A (en) * 1991-03-18 1991-10-08 Dickie Robert G Disposable dental matrix retainer clamp

Also Published As

Publication number Publication date
FI962813A7 (en) 1996-07-11
JPH09508116A (en) 1997-08-19
FI962813L (en) 1996-07-11
NZ259584A (en) 1998-01-26
AU5842594A (en) 1995-08-08
AU707019B2 (en) 1999-07-01
SK91696A3 (en) 1997-04-09
PL175343B1 (en) 1998-12-31
FI962813A0 (en) 1996-07-11
WO1995019780A1 (en) 1995-07-27
CN1142186A (en) 1997-02-05
PL315513A1 (en) 1996-11-12
NO963029D0 (en) 1996-07-19
EP0740552A1 (en) 1996-11-06

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