NO963389L - Antiparasitic agents - Google Patents

Antiparasitic agents

Info

Publication number
NO963389L
NO963389L NO963389A NO963389A NO963389L NO 963389 L NO963389 L NO 963389L NO 963389 A NO963389 A NO 963389A NO 963389 A NO963389 A NO 963389A NO 963389 L NO963389 L NO 963389L
Authority
NO
Norway
Prior art keywords
cjj
formula
organic radical
represent
antiparasitic agents
Prior art date
Application number
NO963389A
Other languages
Norwegian (no)
Other versions
NO963389D0 (en
Inventor
Nigel Derek Walshe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO963389D0 publication Critical patent/NO963389D0/en
Publication of NO963389L publication Critical patent/NO963389L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Antiparasittiske avermectin- og milbemycinderivater med formel (I), hvor de stiplede linjer hver uavhengig betyr en valgfri binding, R1 og RJ ikke forekommer når Cjj-Cjj-dobbeltbindingen forekommer; R1, R2 og R6 hver uavhengig betyr H, OH, halogen, oksimino eller et organisk radikal; R4 og Rs betyr organiske radikaler; R3 betyr H eller et organisk radikal, og A og B kan være en av et vidt spektrum av substituenter, fremstilles ved å omsette en forbindelse med formel (I), hvor A betyr en valgfritt substituert hydrazongruppe, med en elektrofil art for å tilveiebringe substitusjon i 3- stillingen, om nødvendig etterfulgt av ytterligere syntesetrinn.Antiparasitic avermectin and milbemycin derivatives of formula (I), wherein the dotted lines each independently represent an optional bond, R1 and RJ not occurring when the Cjj-Cjj double bond occurs; R 1, R 2 and R 6 each independently means H, OH, halogen, oxymino or an organic radical; R 4 and R 5 represent organic radicals; R 3 represents H or an organic radical, and A and B may be one of a wide range of substituents, prepared by reacting a compound of formula (I), wherein A represents an optionally substituted hydrazone group, with an electrophilic species to provide substitution in the 3 position, if necessary, followed by additional synthesis steps.

NO963389A 1994-02-16 1996-08-14 Antiparasitic agents NO963389L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9402916A GB9402916D0 (en) 1994-02-16 1994-02-16 Antiparasitic agents
PCT/EP1995/000383 WO1995022552A1 (en) 1994-02-16 1995-02-01 Antiparasitic agents

Publications (2)

Publication Number Publication Date
NO963389D0 NO963389D0 (en) 1996-08-14
NO963389L true NO963389L (en) 1996-08-14

Family

ID=10750420

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963389A NO963389L (en) 1994-02-16 1996-08-14 Antiparasitic agents

Country Status (30)

Country Link
US (1) US5723488A (en)
EP (1) EP0745089B1 (en)
JP (2) JP3194959B2 (en)
KR (1) KR100196751B1 (en)
CN (1) CN1043996C (en)
AP (1) AP547A (en)
AT (1) ATE174340T1 (en)
AU (1) AU686326B2 (en)
CA (1) CA2183453C (en)
CZ (1) CZ241496A3 (en)
DE (1) DE69506525T2 (en)
DK (1) DK0745089T3 (en)
EG (1) EG20774A (en)
ES (1) ES2124529T3 (en)
FI (1) FI963201A7 (en)
GB (1) GB9402916D0 (en)
HU (1) HUT76521A (en)
IL (1) IL112596A0 (en)
MA (1) MA23452A1 (en)
MX (1) MX9603486A (en)
NO (1) NO963389L (en)
NZ (1) NZ279494A (en)
OA (1) OA10309A (en)
PL (1) PL315902A1 (en)
RU (1) RU2134272C1 (en)
SI (1) SI9520021A (en)
SK (1) SK106096A3 (en)
WO (1) WO1995022552A1 (en)
YU (1) YU8795A (en)
ZA (1) ZA951218B (en)

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