NO965123L - Pantropiske, neurotrofiske faktorer - Google Patents

Pantropiske, neurotrofiske faktorer

Info

Publication number
NO965123L
NO965123L NO965123A NO965123A NO965123L NO 965123 L NO965123 L NO 965123L NO 965123 A NO965123 A NO 965123A NO 965123 A NO965123 A NO 965123A NO 965123 L NO965123 L NO 965123L
Authority
NO
Norway
Prior art keywords
pantropic
neurotrophic factors
neurotrophic
factors
useful
Prior art date
Application number
NO965123A
Other languages
English (en)
Other versions
NO965123D0 (no
NO317938B1 (no
Inventor
Roman Urfer
Leonard G Presta
John W Winslow
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22962278&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO965123(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO965123D0 publication Critical patent/NO965123D0/no
Publication of NO965123L publication Critical patent/NO965123L/no
Publication of NO317938B1 publication Critical patent/NO317938B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO19965123A 1994-06-03 1996-12-02 Pantropisk neurotrofinpolypeptid, fremgangsmate for fremstilling av dette, isolert nukleinsyre, ekspresjonsvektor, vertscelle samt farmasoytisk preparat NO317938B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25393794A 1994-06-03 1994-06-03
PCT/US1995/006918 WO1995033829A1 (en) 1994-06-03 1995-06-01 Pantropic neurotrophic factors

Publications (3)

Publication Number Publication Date
NO965123D0 NO965123D0 (no) 1996-12-02
NO965123L true NO965123L (no) 1997-02-03
NO317938B1 NO317938B1 (no) 2005-01-10

Family

ID=22962278

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19965123A NO317938B1 (no) 1994-06-03 1996-12-02 Pantropisk neurotrofinpolypeptid, fremgangsmate for fremstilling av dette, isolert nukleinsyre, ekspresjonsvektor, vertscelle samt farmasoytisk preparat

Country Status (17)

Country Link
US (6) US5728803A (no)
EP (1) EP0763107B1 (no)
JP (1) JPH10501138A (no)
CN (1) CN1159439C (no)
AT (1) ATE280825T1 (no)
AU (1) AU695144B2 (no)
BR (1) BR9508019B1 (no)
CA (1) CA2191064C (no)
DE (1) DE69533698T2 (no)
ES (1) ES2231786T3 (no)
FI (1) FI120237B (no)
IL (1) IL113983A0 (no)
MX (1) MX9605971A (no)
NO (1) NO317938B1 (no)
NZ (1) NZ287762A (no)
PT (1) PT763107E (no)
WO (1) WO1995033829A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728803A (en) * 1994-06-03 1998-03-17 Genentech, Inc. Pantropic neurotrophic factors
DE19637718A1 (de) * 1996-04-01 1997-10-02 Boehringer Mannheim Gmbh Rekombinante inaktive Core-Streptavidin Mutanten
AU729459B2 (en) 1996-11-15 2001-02-01 Genentech Inc. Purification of neurotrophins
US6391571B1 (en) 1997-04-01 2002-05-21 Roche Diagnostics Gmbh Recombinant inactive avidin mutants
JP2001527402A (ja) * 1997-04-25 2001-12-25 ジェネンテック，インコーポレーテッド Ｎｇｆ変異体
US6365373B2 (en) 1997-04-25 2002-04-02 Genentech, Inc. Nucleic acids encoding NGF variants
US7452863B1 (en) 1997-04-29 2008-11-18 Genentech, Inc. NGF variants
US6663899B2 (en) 1997-06-13 2003-12-16 Genentech, Inc. Controlled release microencapsulated NGF formulation
US6113947A (en) * 1997-06-13 2000-09-05 Genentech, Inc. Controlled release microencapsulated NGF formulation
US20040120891A1 (en) * 1998-12-21 2004-06-24 Craig Hill Compounds for intracellular delivery of therapeutic moieties to nerve cells
US6652864B1 (en) * 1998-12-21 2003-11-25 Asilomar Pharmaceuticals, Inc. Compounds for intracellular delivery of therapeutic moieties to nerve cells
GB0024550D0 (no) 2000-10-06 2000-11-22 Oxford Biomedica Ltd
KR20100132559A (ko) * 2001-05-30 2010-12-17 제넨테크, 인크. 다양한 질환의 치료에 유용한 항-엔지에프 항체
AU2003259846A1 (en) * 2002-08-16 2004-03-03 The General Hospital Corporation Non-invasive functional imaging of peripheral nervous system activation in humans and animals
DK1891966T3 (da) 2002-12-20 2012-04-02 Lundbeck & Co As H Modulation af neurotrophinaktivitet; fremgangsmåde til screening
EP1841858A4 (en) * 2004-12-30 2010-02-10 Univ Johns Hopkins PROCESS FOR HIGHLY EFFICIENT SURVIVAL OR BZW. For the highly efficient proliferation of human embryonic stem cells in culture
PL3225251T3 (pl) 2006-12-21 2020-06-29 H. Lundbeck A/S Modulacja aktywności proneurotrofin
WO2009062149A1 (en) * 2007-11-08 2009-05-14 Creighton University Methods for maintaining inner ear neurons
US8447409B2 (en) * 2008-10-15 2013-05-21 Cochlear Limited Electroneural interface for a medical implant
US8259461B2 (en) * 2008-11-25 2012-09-04 Micron Technology, Inc. Apparatus for bypassing faulty connections
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9783601B2 (en) 2010-12-01 2017-10-10 Alderbio Holdings Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
CN109071678B (zh) * 2016-03-18 2022-05-20 舒泰神（北京）生物制药股份有限公司 神经生长因子融合蛋白、制备方法及其用途
CN107286233B (zh) * 2016-04-13 2020-11-06 舒泰神（北京）生物制药股份有限公司 低痛神经生长因子突变体
WO2018140792A2 (en) * 2017-01-27 2018-08-02 Otonomy, Inc. Neurotrophin mutants for treating hearing loss and other otic disorders
CN110183536B (zh) * 2018-02-22 2021-01-15 中国科学院遗传与发育生物学研究所 一种复合支架材料及其应用
MX2021000644A (es) 2018-07-18 2021-08-19 Manzanita Pharmaceuticals Inc Conjugados para suministrar un agente contra el cancer a las celulas nerviosas, metodos de uso y metodos para la elaboracion de los mismos.
CN110812532A (zh) * 2019-08-20 2020-02-21 中山大学 一种靶向促进皮质脊髓束连接以修复脊髓损伤的组织工程支架的构建方法
EP4188945A4 (en) * 2020-07-27 2024-10-02 Human Cell Co. NGF VARIANTS, PRODUCTION, COMPOSITIONS AND THERAPEUTIC USES

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169764A (en) * 1990-08-08 1992-12-08 Regeneron Pharmaceuticals, Inc. Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
US5488099A (en) * 1992-03-06 1996-01-30 Persson, Deceased; Hakan B. Multifunctional chimeric neurotrophic factors
US5349055A (en) * 1992-03-06 1994-09-20 Persson Hakan B Nerve growth factor having altered receptor binding specificities
EP0644937A4 (en) * 1992-06-12 1995-05-03 Regeneron Pharmaceuticals, Inc. Therapeutic and diagnostic methods based on neurotrophin-4 expression.
US5753225A (en) 1993-12-03 1998-05-19 The Regents Of The University Of California Antibodies that mimic actions of neurotrophins
AU1282895A (en) * 1993-12-29 1995-07-17 Sumitomo Pharmaceuticals Company, Limited Novel human ciliary neurotrophic factor
US5728803A (en) * 1994-06-03 1998-03-17 Genentech, Inc. Pantropic neurotrophic factors
US7144983B1 (en) * 1997-02-03 2006-12-05 Genentech, Inc. Pantropic neurotrophic factors

Also Published As

Publication number Publication date
US7528233B2 (en) 2009-05-05
PT763107E (pt) 2005-02-28
FI964833L (fi) 1996-12-03
CA2191064A1 (en) 1995-12-14
DE69533698D1 (de) 2004-12-02
FI120237B (fi) 2009-08-14
EP0763107A1 (en) 1997-03-19
JPH10501138A (ja) 1998-02-03
ES2231786T3 (es) 2005-05-16
US6503728B1 (en) 2003-01-07
MX9605971A (es) 1997-12-31
US20100184656A1 (en) 2010-07-22
BR9508019A (pt) 1997-09-09
NO965123D0 (no) 1996-12-02
DE69533698T2 (de) 2006-02-09
BR9508019B1 (pt) 2012-06-12
AU2659295A (en) 1996-01-04
CN1153528A (zh) 1997-07-02
US5728803A (en) 1998-03-17
US7935671B2 (en) 2011-05-03
AU695144B2 (en) 1998-08-06
NO317938B1 (no) 2005-01-10
US20060270838A1 (en) 2006-11-30
US6333310B1 (en) 2001-12-25
EP0763107B1 (en) 2004-10-27
US5981480A (en) 1999-11-09
FI964833A0 (fi) 1996-12-03
IL113983A0 (en) 1995-10-31
NZ287762A (en) 1999-01-28
CA2191064C (en) 2009-11-03
ATE280825T1 (de) 2004-11-15
WO1995033829A1 (en) 1995-12-14
CN1159439C (zh) 2004-07-28

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