NO970665L - Blod billeddannende sammensetninger, anvendelse og fremgangsmåte - Google Patents
Blod billeddannende sammensetninger, anvendelse og fremgangsmåteInfo
- Publication number
- NO970665L NO970665L NO970665A NO970665A NO970665L NO 970665 L NO970665 L NO 970665L NO 970665 A NO970665 A NO 970665A NO 970665 A NO970665 A NO 970665A NO 970665 L NO970665 L NO 970665L
- Authority
- NO
- Norway
- Prior art keywords
- compositions
- circulation
- mixed micelles
- mri
- physiologically acceptable
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000003384 imaging method Methods 0.000 title abstract 4
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000693 micelle Substances 0.000 abstract 4
- 210000000056 organ Anatomy 0.000 abstract 3
- 239000002872 contrast media Substances 0.000 abstract 2
- 210000004204 blood vessel Anatomy 0.000 abstract 1
- 238000011847 diagnostic investigation Methods 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000003307 reticuloendothelial effect Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95810403 | 1995-06-15 | ||
| PCT/IB1996/000577 WO1997000087A1 (en) | 1995-06-15 | 1996-06-14 | Blood-pool imaging compositions use and method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO970665D0 NO970665D0 (no) | 1997-02-13 |
| NO970665L true NO970665L (no) | 1997-04-03 |
| NO314127B1 NO314127B1 (no) | 2003-02-03 |
Family
ID=8221760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19970665A NO314127B1 (no) | 1995-06-15 | 1997-02-13 | Injiserbare NMR-billeddannende sammensetninger, fremgangsmåter for fremstilling og anvendelse av disse |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5833948A (no) |
| EP (1) | EP0804251B1 (no) |
| JP (1) | JP4335976B2 (no) |
| KR (1) | KR100399712B1 (no) |
| AT (1) | ATE224737T1 (no) |
| AU (1) | AU708328B2 (no) |
| CA (1) | CA2195633C (no) |
| DE (1) | DE69623929T2 (no) |
| ES (1) | ES2180784T3 (no) |
| NO (1) | NO314127B1 (no) |
| PT (1) | PT804251E (no) |
| WO (1) | WO1997000087A1 (no) |
| ZA (1) | ZA965101B (no) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1297034B1 (it) * | 1997-12-30 | 1999-08-03 | Bracco Spa | Acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico |
| IT1297035B1 (it) * | 1997-12-30 | 1999-08-03 | Bracco Spa | Derivati dell'acido 1,4,7,10-tetraazaciclododecan-1,4-diacetico |
| US6342598B1 (en) | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
| IT1304501B1 (it) * | 1998-12-23 | 2001-03-19 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza |
| AU2001266696A1 (en) | 2000-06-02 | 2001-12-11 | Bracco Research Usa | Compounds for targeting endothelial cells |
| US6984395B2 (en) * | 2001-04-11 | 2006-01-10 | Qlt, Inc. | Drug delivery system for hydrophobic drugs |
| US20070128253A1 (en) * | 2005-04-13 | 2007-06-07 | Ramaekers Joseph C | Encapsulated transfer factor compositions and methods of use |
| US20060073197A1 (en) * | 2004-05-20 | 2006-04-06 | Ramaekers Joseph C | Encapsulated transfer factor compositions and methods of use |
| US6506413B1 (en) * | 2001-04-30 | 2003-01-14 | Joseph C. Ramaekers | Compositions for treating animal diseases and syndromes |
| US6803046B2 (en) | 2002-08-16 | 2004-10-12 | Bracco International B.V. | Sincalide formulations |
| US7553930B2 (en) * | 2003-01-06 | 2009-06-30 | Xencor, Inc. | BAFF variants and methods thereof |
| US20050221443A1 (en) * | 2003-01-06 | 2005-10-06 | Xencor, Inc. | Tumor necrosis factor super family agonists |
| US20050130892A1 (en) * | 2003-03-07 | 2005-06-16 | Xencor, Inc. | BAFF variants and methods thereof |
| US20060014248A1 (en) * | 2003-01-06 | 2006-01-19 | Xencor, Inc. | TNF super family members with altered immunogenicity |
| JP4670083B2 (ja) | 2003-02-04 | 2011-04-13 | ブラッコ・シュイス・ソシエテ・アノニム | 超音波造影剤およびその製造方法 |
| EP1675871A2 (en) | 2003-10-10 | 2006-07-05 | Xencor Inc. | Protein based tnf-alpha variants for the treatment of tnf-alpha related disorders |
| CN100563718C (zh) | 2003-12-22 | 2009-12-02 | 伯拉考开发股份有限公司 | 用于反差成像的充气微囊组件 |
| US20050152842A1 (en) * | 2003-12-24 | 2005-07-14 | Chun Li | Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent |
| EP1750671B1 (en) * | 2004-06-03 | 2008-10-15 | Bracco Research S.A. | Liposomal assembly for therapeutic and/or diagnostic use |
| US9248204B2 (en) | 2004-08-18 | 2016-02-02 | Bracco Suisse S.A. | Gas-filled microvesicles composition for contrast imaging |
| FR2883562B1 (fr) | 2005-03-24 | 2009-02-27 | Guerbet Sa | Chelates lipophiles et leur utilisation en imagerie |
| RU2007140391A (ru) * | 2005-04-01 | 2009-05-10 | Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем (Us) | Поли(пептид) как хелатор: способы получения и применения |
| EP1898958A2 (en) * | 2005-05-31 | 2008-03-19 | INBIOS S.r.l. | Supramolecular aggregates containing chelating agents and bioactive peptides as effective and selective delivery tools for drugs and contrast agents in mri or nuclear medicine |
| US20090053197A1 (en) * | 2006-06-14 | 2009-02-26 | Ramaekers Joseph C | Transfer Factor Compositions and Methods |
| US9125874B2 (en) | 2007-11-30 | 2015-09-08 | The Ramaekers Family Trust | Administration of transfer factor for improving reproductive health |
| ATE469660T1 (de) | 2006-09-05 | 2010-06-15 | Bracco Research Sa | Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden |
| GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
| US20090074751A1 (en) * | 2007-09-18 | 2009-03-19 | Ramaekers Nutrition, Inc. | Growth factor fraction compositions and methods |
| KR101401217B1 (ko) * | 2007-11-07 | 2014-05-28 | 충남대학교산학협력단 | Pe-dtpa의 새로운 용도 |
| MX2010005317A (es) | 2007-11-20 | 2010-06-02 | Ambrx Inc | Polipeptidos de insulina modificados y sus usos. |
| WO2009070788A1 (en) * | 2007-11-30 | 2009-06-04 | The Ramaekers Family Trust | Compositions and methods for enhancing fertility |
| WO2009097559A1 (en) | 2008-01-30 | 2009-08-06 | Histogen, Inc. | Extracellular matrix compositions |
| CN106362171A (zh) | 2009-02-13 | 2017-02-01 | 华盛顿大学 | 用于磁共振成像的钆表现脂质纳米颗粒 |
| WO2010139003A1 (en) * | 2009-06-01 | 2010-12-09 | Commonwealth Scientific And Industrial Research Organisation | Chelating amphiphiles |
| MA34521B1 (fr) | 2010-08-17 | 2013-09-02 | Ambrx Inc | Polypeptides de relaxine modifiés et leurs utilisations |
| EP2639227A1 (en) | 2012-03-14 | 2013-09-18 | Bracco Imaging S.p.A | A new class of diazepine derivative chelating agents and complexes with paramagnetic metals as MRI contrast agents |
| WO2014037498A2 (en) | 2012-09-07 | 2014-03-13 | Bracco Imaging Spa | Paramagnetic solid lipid nanoparticles (pslns) containing metal amphiphilic complexes for mri. |
| WO2014040076A1 (en) | 2012-09-10 | 2014-03-13 | Xencor | Methods of treating neurological diseases |
| EP2934740B1 (en) | 2012-12-21 | 2019-12-11 | Bracco Suisse SA | Gas-filled microvesicles |
| WO2015119642A1 (en) | 2014-02-10 | 2015-08-13 | The Johns Hopkins University | Low oxygen tension enhances endothelial fate of human pluripotent stem cells |
| US10519207B2 (en) | 2015-06-12 | 2019-12-31 | Georgia State University Research Foundation, Inc. | Compositions and methods for treating opioid tolerance |
| US11110063B2 (en) | 2017-08-25 | 2021-09-07 | MAIA Pharmaceuticals, Inc. | Storage stable sincalide formulations |
| US12077780B2 (en) | 2020-02-14 | 2024-09-03 | Allergan Sales, Llc | Conditioned medium from cells cultured under hypoxic conditions and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5387410A (en) * | 1983-03-18 | 1995-02-07 | Mallinckrodt, Inc. | Method for enhancing magnetic resonance with compositions containing paramagnetic elements carried by liposomes |
| US4728575A (en) * | 1984-04-27 | 1988-03-01 | Vestar, Inc. | Contrast agents for NMR imaging |
| US5215680A (en) * | 1990-07-10 | 1993-06-01 | Cavitation-Control Technology, Inc. | Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles |
| JPH06507904A (ja) * | 1991-05-23 | 1994-09-08 | イマアーレクス・フアーマシユーチカル・コーポレーシヨン | 磁気共鳴画像形成用の油脂可溶化合物 |
| US5464696A (en) * | 1992-08-13 | 1995-11-07 | Bracco International B.V. | Particles for NMR imaging |
| US5534241A (en) * | 1993-07-23 | 1996-07-09 | Torchilin; Vladimir P. | Amphipathic polychelating compounds and methods of use |
| US5567410A (en) * | 1994-06-24 | 1996-10-22 | The General Hospital Corporation | Composotions and methods for radiographic imaging |
-
1996
- 1996-06-13 US US08/663,545 patent/US5833948A/en not_active Expired - Lifetime
- 1996-06-14 KR KR1019970700923A patent/KR100399712B1/ko not_active Expired - Fee Related
- 1996-06-14 PT PT96919971T patent/PT804251E/pt unknown
- 1996-06-14 AT AT96919971T patent/ATE224737T1/de not_active IP Right Cessation
- 1996-06-14 JP JP50285697A patent/JP4335976B2/ja not_active Expired - Fee Related
- 1996-06-14 ES ES96919971T patent/ES2180784T3/es not_active Expired - Lifetime
- 1996-06-14 DE DE69623929T patent/DE69623929T2/de not_active Expired - Lifetime
- 1996-06-14 AU AU58431/96A patent/AU708328B2/en not_active Ceased
- 1996-06-14 EP EP96919971A patent/EP0804251B1/en not_active Expired - Lifetime
- 1996-06-14 ZA ZA965101A patent/ZA965101B/xx unknown
- 1996-06-14 CA CA002195633A patent/CA2195633C/en not_active Expired - Fee Related
- 1996-06-14 WO PCT/IB1996/000577 patent/WO1997000087A1/en not_active Ceased
-
1997
- 1997-02-13 NO NO19970665A patent/NO314127B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA965101B (en) | 1997-01-22 |
| JPH10504044A (ja) | 1998-04-14 |
| EP0804251B1 (en) | 2002-09-25 |
| CA2195633C (en) | 2008-09-16 |
| EP0804251A1 (en) | 1997-11-05 |
| ES2180784T3 (es) | 2003-02-16 |
| DE69623929D1 (de) | 2002-10-31 |
| CA2195633A1 (en) | 1997-01-03 |
| US5833948A (en) | 1998-11-10 |
| NO314127B1 (no) | 2003-02-03 |
| AU5843196A (en) | 1997-01-15 |
| KR970704477A (ko) | 1997-09-06 |
| JP4335976B2 (ja) | 2009-09-30 |
| WO1997000087A1 (en) | 1997-01-03 |
| AU708328B2 (en) | 1999-08-05 |
| NO970665D0 (no) | 1997-02-13 |
| PT804251E (pt) | 2003-01-31 |
| KR100399712B1 (ko) | 2004-02-18 |
| DE69623929T2 (de) | 2003-05-15 |
| ATE224737T1 (de) | 2002-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CB | Opposition filed (par. 26,5 patents act) |
Opponent name: AMERSHAM HEALTH AS, POSTBOKS 4220 NYDALEN, 0401 OS Effective date: 20031104 |
|
| ERR | Erratum |
Free format text: I PATENTTIDENDE NR 47 BLE INNSIGELSE I PATENT NR 314127 KUNNGJORT MED FEIL INNSIGELSESDAG. |
|
| MM1K | Lapsed by not paying the annual fees |