NO971991L - Heterosyklus-substituerte propensyrederivater som NMDA-antagonister - Google Patents
Heterosyklus-substituerte propensyrederivater som NMDA-antagonisterInfo
- Publication number
- NO971991L NO971991L NO971991A NO971991A NO971991L NO 971991 L NO971991 L NO 971991L NO 971991 A NO971991 A NO 971991A NO 971991 A NO971991 A NO 971991A NO 971991 L NO971991 L NO 971991L
- Authority
- NO
- Norway
- Prior art keywords
- acid derivatives
- propenoic acid
- heterocycle
- nmda antagonists
- substituted propenoic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08332016 US5563157B1 (en) | 1994-10-31 | 1994-10-31 | Heterocycle substituted propenoic acid derivatives and pharmaceutical compositions thereof |
| PCT/US1995/012085 WO1996013501A1 (en) | 1994-10-31 | 1995-09-21 | Heterocycle substituted propenoic acid derivatives as nmda antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO971991D0 NO971991D0 (no) | 1997-04-29 |
| NO971991L true NO971991L (no) | 1997-04-29 |
| NO313197B1 NO313197B1 (no) | 2002-08-26 |
Family
ID=23296353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19971991A NO313197B1 (no) | 1994-10-31 | 1997-04-29 | Heterosyklus-substituerte propensyrederivater som NMDA- antagonister |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US5563157B1 (no) |
| EP (1) | EP0790994B1 (no) |
| JP (1) | JP3934678B2 (no) |
| KR (1) | KR100401138B1 (no) |
| CN (1) | CN1068001C (no) |
| AT (1) | ATE217307T1 (no) |
| AU (1) | AU696423B2 (no) |
| CA (1) | CA2202992C (no) |
| DE (1) | DE69526668T2 (no) |
| DK (1) | DK0790994T3 (no) |
| ES (1) | ES2173198T3 (no) |
| FI (1) | FI971831A0 (no) |
| HU (1) | HU222372B1 (no) |
| IL (1) | IL115791A (no) |
| MX (1) | MX9703146A (no) |
| NO (1) | NO313197B1 (no) |
| NZ (1) | NZ293842A (no) |
| PT (1) | PT790994E (no) |
| TW (1) | TW336232B (no) |
| WO (1) | WO1996013501A1 (no) |
| ZA (1) | ZA959046B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922752A (en) * | 1997-06-11 | 1999-07-13 | Hoechst Marion Roussell, Inc. | NMDA (n-methyl-d-aspartate) antagonists |
| GB9902455D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| IL154981A0 (en) | 2000-10-10 | 2003-10-31 | Smithkline Beecham Corp | Substituted indoles, pharmaceutical compositions containing such indoles and their use as ppay-y-binding agents |
| JP2005506292A (ja) * | 2001-03-08 | 2005-03-03 | エモリー ユニバーシティ | pHに依存するNMDAレセプターアンタゴニスト |
| KR20100045983A (ko) | 2007-06-29 | 2010-05-04 | 에모리 유니버시티 | 신경보호를 위한 nmda 수용체 길항물질 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU216787B (hu) * | 1990-07-16 | 1999-08-30 | Merrell Dow Pharmaceuticals Inc. | Eljárás excitátoros aminosav-antagonista hatású indolszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
| JP3094450B2 (ja) * | 1990-10-15 | 2000-10-03 | アストラゼネカ・アクチエボラーグ | 神経保護特性を有するピペリジン誘導体 |
| US5284862A (en) * | 1991-03-18 | 1994-02-08 | Warner-Lambert Company | Derivatives of 2-carboxyindoles having pharmaceutical activity |
| GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
| US5519048A (en) * | 1993-05-27 | 1996-05-21 | Merrell Pharmaceuticals Inc. | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof |
| WO1994027964A1 (en) * | 1993-05-27 | 1994-12-08 | Merrell Dow Pharmaceuticals Inc. | 3-(indol-3-yl) propenoic acid derivatives and as nmda antagonists |
-
1994
- 1994-10-31 US US08332016 patent/US5563157B1/en not_active Expired - Lifetime
-
1995
- 1995-09-21 CN CN95195799A patent/CN1068001C/zh not_active Expired - Fee Related
- 1995-09-21 CA CA002202992A patent/CA2202992C/en not_active Expired - Lifetime
- 1995-09-21 KR KR1019970702840A patent/KR100401138B1/ko not_active Expired - Fee Related
- 1995-09-21 ES ES95933902T patent/ES2173198T3/es not_active Expired - Lifetime
- 1995-09-21 EP EP95933902A patent/EP0790994B1/en not_active Expired - Lifetime
- 1995-09-21 DK DK95933902T patent/DK0790994T3/da active
- 1995-09-21 AU AU36387/95A patent/AU696423B2/en not_active Ceased
- 1995-09-21 AT AT95933902T patent/ATE217307T1/de not_active IP Right Cessation
- 1995-09-21 WO PCT/US1995/012085 patent/WO1996013501A1/en not_active Ceased
- 1995-09-21 JP JP51456396A patent/JP3934678B2/ja not_active Expired - Lifetime
- 1995-09-21 MX MX9703146A patent/MX9703146A/es unknown
- 1995-09-21 NZ NZ293842A patent/NZ293842A/en unknown
- 1995-09-21 FI FI971831A patent/FI971831A0/fi not_active IP Right Cessation
- 1995-09-21 DE DE69526668T patent/DE69526668T2/de not_active Expired - Lifetime
- 1995-09-21 HU HU9701941A patent/HU222372B1/hu not_active IP Right Cessation
- 1995-09-21 PT PT95933902T patent/PT790994E/pt unknown
- 1995-10-25 ZA ZA959046A patent/ZA959046B/xx unknown
- 1995-10-26 TW TW084111310A patent/TW336232B/zh active
- 1995-10-27 IL IL11579195A patent/IL115791A/xx not_active IP Right Cessation
-
1997
- 1997-04-29 NO NO19971991A patent/NO313197B1/no not_active IP Right Cessation
- 1997-12-15 US US08/990,673 patent/US5981553A/en not_active Expired - Lifetime
-
1999
- 1999-07-28 US US09/363,305 patent/US6180786B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE217307T1 (de) | 2002-05-15 |
| TW336232B (en) | 1998-07-11 |
| EP0790994A1 (en) | 1997-08-27 |
| DE69526668D1 (de) | 2002-06-13 |
| ZA959046B (en) | 1996-05-17 |
| US5563157B1 (en) | 1999-02-02 |
| NO971991D0 (no) | 1997-04-29 |
| WO1996013501A1 (en) | 1996-05-09 |
| EP0790994B1 (en) | 2002-05-08 |
| HU222372B1 (hu) | 2003-06-28 |
| KR100401138B1 (ko) | 2003-12-24 |
| NO313197B1 (no) | 2002-08-26 |
| MX9703146A (es) | 1997-06-28 |
| PT790994E (pt) | 2002-08-30 |
| CA2202992A1 (en) | 1996-05-09 |
| ES2173198T3 (es) | 2002-10-16 |
| DE69526668T2 (de) | 2003-01-02 |
| CN1161696A (zh) | 1997-10-08 |
| NZ293842A (en) | 1998-09-24 |
| JP3934678B2 (ja) | 2007-06-20 |
| JPH10508019A (ja) | 1998-08-04 |
| FI971831L (fi) | 1997-04-29 |
| FI971831A7 (fi) | 1997-04-29 |
| CA2202992C (en) | 2003-05-13 |
| HUT77174A (hu) | 1998-03-02 |
| IL115791A (en) | 2000-09-28 |
| FI971831A0 (fi) | 1997-04-29 |
| US6180786B1 (en) | 2001-01-30 |
| CN1068001C (zh) | 2001-07-04 |
| US5981553A (en) | 1999-11-09 |
| AU3638795A (en) | 1996-05-23 |
| DK0790994T3 (da) | 2002-08-26 |
| AU696423B2 (en) | 1998-09-10 |
| IL115791A0 (en) | 1996-01-19 |
| US5563157A (en) | 1996-10-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1193270E (pt) | Pirrolobenzodiazepinas | |
| PT1007523E (pt) | Derivados indole e 2,3-di-ridroindole, sua preparacao e utilizacao | |
| DK0977741T3 (da) | Substituerede phenylderivater, deres fremstilling og anvendelse | |
| ATE297203T1 (de) | Antithrombotische mitteln | |
| NO20033732L (no) | N-substituerte ikke-aryl-heterosykliske NMDA/NR2B-antagonister, og farmasoytiske preparater som omfatter slike forbindelser. | |
| YU104690A (sh) | Supstituisani imidazo-kondenzovani 6-člani heterocikli kao antagonisti angiotenzina 2 | |
| DK0889876T3 (da) | Meta-substituerede phenylensulfonamidderivater | |
| FI964815L (fi) | Piperatsiinijohdoksia 5-HT1A antagonisteina | |
| BR9914221B1 (pt) | Derivados de glicopeptídeos e composições farmacêuticas contendo os mesmos | |
| CO4940466A1 (es) | Sales metanosulfonato de 5-(2-(4-(1,2-benzoisotiazol-3-il)- 1-piperazinil)etil)-6-cloro-1,3-dihidro-2h-indol-2-ona dihidratadas | |
| BR0206595A (pt) | Composto, composição farmacêutica, e uso de um composto | |
| GB9718903D0 (en) | Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents | |
| DK0696194T3 (da) | Anvendelse af indolderivater som 5HT1-antagonister | |
| FI972684A7 (fi) | Piperidiinietikkahappojohdannaisia, joita voidaan käyttää fibrinogeeni antagonisteina | |
| NO20014855D0 (no) | N-(2-fenyl-4-aminobutyl)-1-naftamider som neurokinin-1- reseptorantagonister | |
| ATE375985T1 (de) | Oxazolylarylpropionsäure derivate und ihre verwendung als ppar agonisten | |
| NO971991D0 (no) | Heterosyklus-substituerte propensyrederivater som NMDA-antagonister | |
| SE9504662D0 (sv) | New compounds | |
| SE9902387D0 (sv) | New pharmaceutically active compounds | |
| FI955604A7 (fi) | 3-(indol-3-yyli)propenoiinihappojohdannaiset NMDA-antagonisteina | |
| TR200001080T2 (tr) | 2 ile ikame edilmiş 1,2-Benisotiyazol türevleri ve bunların serrotonın antagonistleri | |
| DK0888340T3 (da) | 4-(benzo-1,3-dioxolyl)-pyrrolidin-3-carboxylsyre-derivater som antagonister for enodthelin | |
| DE69526738D1 (de) | Endothelin-rezeptor-antagonisten | |
| PT1104419E (pt) | Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao | |
| DE59803066D1 (de) | Substituierte benzyloxyimino-verbindungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |