NO972278L - Fluorerte vitamin D3-analoger - Google Patents

Fluorerte vitamin D3-analoger

Info

Publication number: NO972278L
Authority: NO; Norway
Prior art keywords: double bond; hydrogen; bond; alkyl; independently
Prior art date: 1996-05-23

Application number

NO972278A

Other languages

English (en)

Norwegian (no)

Other versions

NO972278D0 (no

Inventor

Percy Sarwood Manchand

Jr John Joseph Nestor

Milan Radoje Uskokovic

Brian Henry Vickery

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-05-23

Filing date

1997-05-20

Publication date

1997-11-24

1997-05-20 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-05-20 Publication of NO972278D0 publication Critical patent/NO972278D0/no

1997-11-24 Publication of NO972278L publication Critical patent/NO972278L/no

Links

QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 14
239000001257 hydrogen Substances 0.000 abstract 8
150000002431 hydrogen Chemical class 0.000 abstract 6
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000003709 fluoroalkyl group Chemical group 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Nutrition Science (AREA)
Hematology (AREA)
Obesity (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO972278A 1996-05-23 1997-05-20 Fluorerte vitamin D3-analoger NO972278L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1821996P	1996-05-23	1996-05-23
US3990197P	1997-03-19	1997-03-19

Publications (2)

Publication Number	Publication Date
NO972278D0 NO972278D0 (no)	1997-05-20
NO972278L true NO972278L (no)	1997-11-24

Family

ID=26690870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO972278A NO972278L (no)	1996-05-23	1997-05-20	Fluorerte vitamin D3-analoger

Country Status (26)

Country	Link
EP (1)	EP0808832B1 (fr)
JP (1)	JP2859248B2 (fr)
KR (1)	KR100253961B1 (fr)
CN (1)	CN100402497C (fr)
AR (1)	AR007776A1 (fr)
AT (1)	ATE238278T1 (fr)
AU (1)	AU733970B2 (fr)
BR (1)	BR9703385A (fr)
CA (1)	CA2205315C (fr)
CO (1)	CO4940503A1 (fr)
CZ (1)	CZ157797A3 (fr)
DE (1)	DE69721123T2 (fr)
DK (1)	DK0808832T3 (fr)
ES (1)	ES2195049T3 (fr)
HR (1)	HRP970272A2 (fr)
HU (1)	HUP9700928A3 (fr)
IL (1)	IL120844A0 (fr)
MA (1)	MA24250A1 (fr)
NO (1)	NO972278L (fr)
NZ (1)	NZ314840A (fr)
PE (1)	PE66798A1 (fr)
PL (1)	PL320130A1 (fr)
PT (1)	PT808832E (fr)
SG (1)	SG70010A1 (fr)
TR (1)	TR199700416A2 (fr)
YU (1)	YU20097A (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6008209A (en) *	1997-04-28	1999-12-28	Hoffmann-La Roche Inc.	Method of using vitamin D3 analogs with bis C-20 side chains
DE19935771A1 (de)	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
AU2001278744A1 (en) *	2000-08-17	2002-02-25	Chugai Seiyaku Kabushiki Kaisha	Remedial agent for osteoporosis
JP2005503434A (ja) *	2001-09-21	2005-02-03	エフ．ホフマン−ラ　ロシュ　アーゲー	３−デスオキシ−ビタミンｄ３類似体
AU2004203436A1 (en)	2003-09-24	2005-04-14	Bioxell Spa	Compound and use in treatment
CN101106985A (zh) *	2004-09-24	2008-01-16	拜奥艾克塞尔股份公司	20－环烷基，26,27－烷基/卤代烷基维生素d3化合物及其使用方法
WO2006102647A1 (fr) *	2005-03-23	2006-09-28	Bioxell S.P.A.	Vitamine d3 gemini 20-alkyle, composes et procedes d’utilisation
PL2634171T3 (pl) *	2010-10-25	2015-12-31	Teijin Ltd	23-ynowa pochodna witaminy D3

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4141746A1 (de) *	1991-12-13	1993-06-17	Schering Ag	20-methyl-substituierte vitamin d-derivate
DE4220757A1 (de) *	1992-06-24	1994-01-05	Schering Ag	Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
US5428029A (en) *	1993-11-24	1995-06-27	Hoffmann-La Roche Inc.	Vitamin D3 fluorinated analogs
US5384314B1 (en) *	1994-03-11	1997-08-05	Hoffmann La Roche	1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
AU7295696A (en) *	1995-10-27	1997-05-22	F. Hoffmann-La Roche Ag	Pharmaceutical composition for treating osteoporosis

1997
- 1997-05-12 SG SG1997001484A patent/SG70010A1/en unknown
- 1997-05-14 PT PT97107868T patent/PT808832E/pt unknown
- 1997-05-14 DE DE69721123T patent/DE69721123T2/de not_active Expired - Lifetime
- 1997-05-14 ES ES97107868T patent/ES2195049T3/es not_active Expired - Lifetime
- 1997-05-14 DK DK97107868T patent/DK0808832T3/da active
- 1997-05-14 EP EP97107868A patent/EP0808832B1/fr not_active Expired - Lifetime
- 1997-05-14 AT AT97107868T patent/ATE238278T1/de not_active IP Right Cessation
- 1997-05-14 CA CA002205315A patent/CA2205315C/fr not_active Expired - Fee Related
- 1997-05-16 PE PE1997000387A patent/PE66798A1/es not_active Application Discontinuation
- 1997-05-16 NZ NZ314840A patent/NZ314840A/en unknown
- 1997-05-16 IL IL12084497A patent/IL120844A0/xx unknown
- 1997-05-20 YU YU20097A patent/YU20097A/sh unknown
- 1997-05-20 NO NO972278A patent/NO972278L/no unknown
- 1997-05-20 HR HR60/039,901A patent/HRP970272A2/xx not_active Application Discontinuation
- 1997-05-21 MA MA24631A patent/MA24250A1/fr unknown
- 1997-05-21 HU HU9700928A patent/HUP9700928A3/hu unknown
- 1997-05-21 AR ARP970102159A patent/AR007776A1/es active IP Right Grant
- 1997-05-22 JP JP9131810A patent/JP2859248B2/ja not_active Expired - Fee Related
- 1997-05-22 CZ CZ971577A patent/CZ157797A3/cs unknown
- 1997-05-22 KR KR1019970020029A patent/KR100253961B1/ko not_active Expired - Fee Related
- 1997-05-22 CO CO97028096A patent/CO4940503A1/es unknown
- 1997-05-22 CN CNB971134324A patent/CN100402497C/zh not_active Expired - Fee Related
- 1997-05-22 PL PL97320130A patent/PL320130A1/xx unknown
- 1997-05-22 AU AU23576/97A patent/AU733970B2/en not_active Ceased
- 1997-05-23 TR TR97/00416A patent/TR199700416A2/xx unknown
- 1997-05-23 BR BR9703385A patent/BR9703385A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2205315C (fr)	2006-10-24
IL120844A0 (en)	1997-09-30
PL320130A1 (en)	1997-11-24
EP0808832A3 (fr)	1999-02-03
KR970074764A (ko)	1997-12-10
PT808832E (pt)	2003-07-31
HRP970272A2 (en)	1998-04-30
JPH1045714A (ja)	1998-02-17
DE69721123T2 (de)	2004-01-08
DK0808832T3 (da)	2003-08-11
DE69721123D1 (de)	2003-05-28
KR100253961B1 (ko)	2000-04-15
TR199700416A2 (xx)	1997-12-21
ES2195049T3 (es)	2003-12-01
CN100402497C (zh)	2008-07-16
JP2859248B2 (ja)	1999-02-17
AU733970B2 (en)	2001-05-31
CA2205315A1 (fr)	1997-11-23
CN1172801A (zh)	1998-02-11
CO4940503A1 (es)	2000-07-24
HUP9700928A3 (en)	1999-07-28
CZ157797A3 (en)	1997-12-17
MX9703775A (es)	1998-06-30
HUP9700928A2 (hu)	1998-01-28
BR9703385A (pt)	1998-09-15
YU20097A (sh)	1999-09-27
AU2357697A (en)	1997-11-27
NZ314840A (en)	1998-11-25
AR007776A1 (es)	1999-11-24
EP0808832B1 (fr)	2003-04-23
NO972278D0 (no)	1997-05-20
PE66798A1 (es)	1998-10-22
HU9700928D0 (en)	1997-07-28
MA24250A1 (fr)	1998-04-01
SG70010A1 (en)	2000-01-25
EP0808832A2 (fr)	1997-11-26
ATE238278T1 (de)	2003-05-15

Publication	Publication Date	Title
HU9401950D0 (en)	1994-09-28	New aryl- and heteroaryl-ethylene derivatives and process for producing them
DE69208078D1 (de)	1996-03-14	Fluorierte kohlenwasserstoffderivate, ihre verwendung in kosmetischen zusammensetzungen, verfahren zu ihrer herstellung und sie enthaltende kosmetische zusammensetzungen
DK0707472T3 (da)	2001-04-17	Fremgangsmåde til regulering af størrelsen af liposomer
NO972278L (no)	1997-11-24	Fluorerte vitamin D3-analoger
ID18576A (id)	1998-04-23	Senyawa antara untuk membuat turunan-turunan steroid yang digunakan dalam pengobatan hipertropi prostatik dan pembuatannya
DE3762615D1 (de)	1990-06-13	Verfahren zur herstellung von (2,2)-paracyclophan und dessen derivaten.
GB2283016A (en)	1995-04-26	Scavenging of hydrogen sulphide
IL83141A (en)	1992-11-15	Solutions of oxazophosphorins having improved stability and their preparation
ES8601843A1 (es)	1985-11-16	Procedimiento para el tratamiento de textiles
AU6559994A (en)	1994-11-21	Stable moulding or spinning compound containing cellulose
GB1477293A (en)	1977-06-22	Tetralone and indanone derivatives and process for their preparations
AU1706495A (en)	1995-09-11	Stabilizer mixture made up of chromane derivatives, organic phosphites or phosphonites and amines
EA199800468A1 (ru)	1998-12-24	25-гидрокси-16-ен-26,27-бисгомохолекальциферолы
HU9502179D0 (en)	1995-09-28	Piperazine derivatives for producing alkyl-trazodon derivatives and process for producing them
AU683148B2 (en)	1997-10-30	Cyclohexane derivatives, process for their preparation, and the use of the compounds for the treatment of diseases
JPS5735506A (en)	1982-02-26	Bleaching cosmetic
NO940113L (no)	1994-03-11	Syntese av 2-fenyl-substituerte 1,3-propandioler
FI832007A0 (fi)	1983-06-03	En ny mikroorganismstam chromobacterium violaceum, medelst denna stam framstaellda farmaceutiskt aktiva foereningar, ett foerfarande foer framstaellning av foereningarna och anvaendning av dessa foereningar som laekemedel
JPS5745169A (en)	1982-03-13	Benzotriazole compound and its preparation
ES2150564T3 (es)	2000-12-01	Proceso para la preparacion de derivados de 5,6-dihidroxi-2-amino-1,2,3,4-tetrahidronaftaleno.
SU1837613A1 (ru)	1996-04-27	Гидрофобизатор для обработки бетона
US4268669A (en)	1981-05-19	9-Deoxy-9-methylene-5,6-didehydro-PGF1 amides
JPS56152827A (en)	1981-11-26	Stabilized polyurethane
MX9603450A (es)	1997-03-29	Procedimiento para la obtencion de aminotriazolinas substituidas.
UA18619A (uk)	1997-12-25	Спосіб одержаhhя сірки