NO972716L - Modulator av funksjonen til FAS/APO1 reseptorer - Google Patents

Modulator av funksjonen til FAS/APO1 reseptorer

Info

Publication number
NO972716L
NO972716L NO972716A NO972716A NO972716L NO 972716 L NO972716 L NO 972716L NO 972716 A NO972716 A NO 972716A NO 972716 A NO972716 A NO 972716A NO 972716 L NO972716 L NO 972716L
Authority
NO
Norway
Prior art keywords
fas
function
modulator
apo1
receptors
Prior art date
Application number
NO972716A
Other languages
English (en)
Other versions
NO972716D0 (no
NO324725B1 (no
Inventor
David Wallach
Mark Boldin
Eugene Varfolomeev
Igor Mett
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL11200294A external-priority patent/IL112002A0/xx
Priority claimed from IL112692A external-priority patent/IL112692A/en
Priority claimed from IL11461595A external-priority patent/IL114615A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO972716D0 publication Critical patent/NO972716D0/no
Publication of NO972716L publication Critical patent/NO972716L/no
Publication of NO324725B1 publication Critical patent/NO324725B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transmitters (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Radar Systems Or Details Thereof (AREA)
NO19972716A 1994-12-15 1997-06-12 MORT-1-protein, DNA-sekvens som koder for MORT-1 og antistoffer spesifikke for MORT-1, samt fremgangsmate for fremstilling, farmasoytiske sammensetninger og anvendelser. NO324725B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL11200294A IL112002A0 (en) 1994-05-11 1994-12-15 Modulatiors of tnf/ngf superfamily receptors, their preparation and use
IL112692A IL112692A (en) 1995-02-19 1995-02-19 ANTIBODIES TO PROTEIN WHICH BINDS TO Fas-R
IL11461595A IL114615A0 (en) 1995-07-16 1995-07-16 Modulators of the function of fas receptors and other proteins
PCT/US1995/016542 WO1996018641A1 (en) 1994-12-15 1995-12-14 Modulators of the function of fas/apo1 receptors

Publications (3)

Publication Number Publication Date
NO972716D0 NO972716D0 (no) 1997-06-12
NO972716L true NO972716L (no) 1997-07-11
NO324725B1 NO324725B1 (no) 2007-12-03

Family

ID=27271687

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19972716A NO324725B1 (no) 1994-12-15 1997-06-12 MORT-1-protein, DNA-sekvens som koder for MORT-1 og antistoffer spesifikke for MORT-1, samt fremgangsmate for fremstilling, farmasoytiske sammensetninger og anvendelser.

Country Status (17)

Country Link
EP (1) EP0871645B1 (no)
JP (1) JP3787355B2 (no)
KR (1) KR100536394B1 (no)
CN (1) CN1105725C (no)
AT (1) ATE377073T1 (no)
AU (1) AU706401B2 (no)
CA (1) CA2207815C (no)
CY (1) CY2586B2 (no)
DE (1) DE69535634T2 (no)
DK (1) DK0871645T3 (no)
ES (1) ES2292172T3 (no)
FI (1) FI121273B (no)
MX (1) MX9704501A (no)
NO (1) NO324725B1 (no)
PT (1) PT871645E (no)
UA (1) UA58489C2 (no)
WO (1) WO1996018641A1 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
US7097972B1 (en) 1995-02-13 2006-08-29 Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6015665A (en) * 1995-02-13 2000-01-18 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6060238A (en) * 1995-02-13 2000-05-09 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
WO1996025941A1 (en) * 1995-02-22 1996-08-29 Yeda Research And Development Co. Ltd. Modulators of regulatory proteins
AU755662B2 (en) * 1995-02-22 2002-12-19 Yeda Research And Development Co. Ltd. Modulators of regulatory proteins
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
US7807783B1 (en) * 1995-04-03 2010-10-05 The Regents Of The University Of Michigan Methods and compositions for regulating FAS-associated apoptosis
US6399327B1 (en) 1995-07-16 2002-06-04 Yeda Research And Development Co. Ltd. Modulators of the function of FAS receptors and other proteins
US6911526B2 (en) * 1996-07-22 2005-06-28 The Trustees Of Columbia University In The City Of New York Compounds that inhibit the interaction between signal-transducing proteins and the GLGF (PDZ/DHR) domain and uses thereof
EP0842665A3 (en) * 1996-11-14 2002-12-18 Smithkline Beecham Corporation Interleukin-1 beta converting enzyme like apoptotic proteases and their agonists
US5969102A (en) 1997-03-03 1999-10-19 St. Jude Children's Research Hospital Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof
DK0977846T3 (da) * 1997-04-25 2002-10-14 Wyeth Corp Neuronale MORT1-isoformer
WO1999000499A1 (en) * 1997-06-26 1999-01-07 Chiron Corporation Human fadd-interacting protein (fip)
US7833529B1 (en) 1999-01-07 2010-11-16 Zymogenetics, Inc. Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
US6015712A (en) * 1999-07-19 2000-01-18 Isis Pharmaceuticals Inc. Antisense modulation of FADD expression
PL403488A1 (pl) 2001-05-24 2013-07-08 Zymogenetics, Inc. Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina
US6743630B2 (en) 2002-03-06 2004-06-01 The Trustees Of Columbia University In The City Of New York Method of preparing a protein array based on biochemical protein-protein interaction
KR20080056714A (ko) 2005-08-09 2008-06-23 지모제넥틱스, 인코포레이티드 ＴＡＣＩ―Ｉｇ 융합 분자를 사용하여 Ｂ―세포 악성종양을치료하는 방법
US8808696B2 (en) 2005-08-09 2014-08-19 Ares Trading S.A. Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules
WO2007134326A2 (en) 2006-05-15 2007-11-22 Ares Trading S.A. Methods for treating autoimmune diseases using a taci-ig fusion molecule

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO178777C (no) * 1994-05-09 1996-05-29 Kvaerner Eng Varmeveksler
US7807783B1 (en) * 1995-04-03 2010-10-05 The Regents Of The University Of Michigan Methods and compositions for regulating FAS-associated apoptosis
US5674734A (en) * 1995-05-18 1997-10-07 President And Fellows Of Harvard College Cell death protein

Also Published As

Publication number Publication date
EP0871645A1 (en) 1998-10-21
CA2207815C (en) 2011-03-29
DE69535634T2 (de) 2008-08-28
DE69535634D1 (de) 2007-12-13
MX9704501A (es) 1997-10-31
PT871645E (pt) 2007-11-14
CN1105725C (zh) 2003-04-16
AU4602296A (en) 1996-07-03
FI972457L (fi) 1997-06-10
AU706401B2 (en) 1999-06-17
HK1007248A1 (en) 1999-04-09
DK0871645T3 (da) 2007-12-03
WO1996018641A1 (en) 1996-06-20
UA58489C2 (uk) 2003-08-15
NO972716D0 (no) 1997-06-12
FI972457A0 (fi) 1997-06-10
JPH10510712A (ja) 1998-10-20
EP0871645A4 (en) 1999-11-24
NO324725B1 (no) 2007-12-03
EP0871645B1 (en) 2007-10-31
ATE377073T1 (de) 2007-11-15
JP3787355B2 (ja) 2006-06-21
CY2586B2 (en) 2009-11-04
KR100536394B1 (ko) 2006-04-21
FI121273B (fi) 2010-09-15
CN1169729A (zh) 1998-01-07
ES2292172T3 (es) 2008-03-01
CA2207815A1 (en) 1996-06-20

Similar Documents

Publication Publication Date Title
CY2586B2 (en) Modulators of the function of FAS/APO1 receptors
AU1750297A (en) Humanized green fluorescent protein genes and methods
DE69632827D1 (de) Materialen und methoden im zusammenhang mit bindung und präsentation von substanzen auf zelloberflächen
DE69931391D1 (de) Trans-aktivierung und cis-aktivierung um die dauer der expression eines transgens zu modulieren
DE3786592D1 (de) Transformation von trichoderma.
WO1999006557A3 (en) Mammalian cell membrane proteins; related reagents
WO1998021343A8 (en) Genes encoding telomerase proteins
WO1999025878A3 (en) Methods for modulating and identifying cellular senescence
IL133129A0 (en) Prenylcysteine carboxyl methyltransferase dna encoding same and a method of screening for inhibistors thereof
AU4423799A (en) Methods and agents for modulating the immune response and inflammation involvingmonocyte and dendritic cell membrane proteins
WO2005060722A3 (en) Modulation of immune system function by modulation of polypeptide arginine methyltransferases
WO1996007739A3 (en) Interleukin-1 type 3 receptors
AU1908395A (en) Antibodies to mammalian natural killer antigens and uses
AU7423391A (en) Dna constructs for the expression of proteins in the mammary gland of transgenetic mammals
ES8802538A1 (es) Un metodo de producir una proteina capaz de modular la actividad fisiologica de celulas que tienen un receptor de diazepam
WO2000018909A3 (en) NUCLEIC ACIDS AND PROTEINS FROM $i(CENARCHAEUM SYMBIOSUM)
BG104769A (en) Modulators of the function of receptors of the tnf/ngf receptor family and other proteins
DK0868511T3 (da) Genekspression af utrophin
WO1999047709A3 (en) Methods for identifying anti-cancer agents
DK0870015T3 (da) Xylanaser, gener, der koder for disse, samt anvendelser deraf
WO1999024835A3 (en) An immunoassay for procollagen-iii-c-terminal propeptide
AU4365196A (en) Purified genes encoding mammalian cell surface antigens; proteins and antibodies
WO2000034335A3 (en) 'death domain' containing receptors
AU9790398A (en) Mrit family of cell death proteins, nucleic acids encoding same, and methods of use
AU7718294A (en) Mammalian stromal cell proteins and dna sequences coding therefor

Legal Events

Date Code Title Description
MK1K Patent expired