NO973835L - Fremgangsmåte for fremstilling av lorakarbefmonohydrat - Google Patents

Fremgangsmåte for fremstilling av lorakarbefmonohydrat

Info

Publication number
NO973835L
NO973835L NO973835A NO973835A NO973835L NO 973835 L NO973835 L NO 973835L NO 973835 A NO973835 A NO 973835A NO 973835 A NO973835 A NO 973835A NO 973835 L NO973835 L NO 973835L
Authority
NO
Norway
Prior art keywords
preparation
loracarbef monohydrate
loracarbef
monohydrate
Prior art date
Application number
NO973835A
Other languages
English (en)
Other versions
NO308471B1 (no
NO973835D0 (no
Inventor
William C Henning
Theodore R Stout
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO973835L publication Critical patent/NO973835L/no
Publication of NO973835D0 publication Critical patent/NO973835D0/no
Publication of NO308471B1 publication Critical patent/NO308471B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO973835A 1995-03-01 1997-08-20 FremgangsmÕter for fremstilling av lorakarbefmonohydrat og krystallinsk anhydratform av lorakarbef NO308471B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/396,948 US5580977A (en) 1995-03-01 1995-03-01 Process for preparing loracarbef monohydrate
PCT/US1996/002586 WO1996026942A1 (en) 1995-03-01 1996-02-28 A process for preparing loracarbef monohydrate

Publications (3)

Publication Number Publication Date
NO973835L true NO973835L (no) 1997-08-20
NO973835D0 NO973835D0 (no) 1997-08-20
NO308471B1 NO308471B1 (no) 2000-09-18

Family

ID=23569249

Family Applications (1)

Application Number Title Priority Date Filing Date
NO973835A NO308471B1 (no) 1995-03-01 1997-08-20 FremgangsmÕter for fremstilling av lorakarbefmonohydrat og krystallinsk anhydratform av lorakarbef

Country Status (28)

Country Link
US (1) US5580977A (no)
EP (1) EP0729959B1 (no)
JP (1) JPH11501032A (no)
KR (1) KR19980702666A (no)
CN (1) CN1061349C (no)
AR (1) AR002709A1 (no)
AT (1) ATE184006T1 (no)
AU (1) AU694639B2 (no)
BR (1) BR9607308A (no)
CA (1) CA2213812A1 (no)
CO (1) CO4700429A1 (no)
CZ (1) CZ272897A3 (no)
DE (1) DE69603995T2 (no)
DK (1) DK0729959T3 (no)
ES (1) ES2135165T3 (no)
GR (1) GR3031947T3 (no)
HU (1) HUP9702151A3 (no)
IL (1) IL117228A (no)
NO (1) NO308471B1 (no)
NZ (1) NZ304534A (no)
PE (1) PE28097A1 (no)
PL (1) PL322111A1 (no)
RU (1) RU2160261C2 (no)
SI (1) SI0729959T1 (no)
TR (1) TR199700877T1 (no)
TW (1) TW330205B (no)
WO (1) WO1996026942A1 (no)
ZA (1) ZA961341B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69824632T2 (de) 1997-11-12 2005-06-09 Mitsubishi Chemical Corp. Purinderivate und medikamente, welche dieselben als aktiven bestandteil enthalten
KR100747106B1 (ko) 1999-05-11 2007-08-08 미쯔비시 가가꾸 가부시끼가이샤 퓨린 유도체 이수화물, 이를 유효성분으로 함유하는 의약및 이의 제조 중간체
PE20011061A1 (es) 2000-02-01 2001-11-20 Procter & Gamble Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
CA2506872A1 (en) * 2002-11-21 2004-06-03 Ranbaxy Laboratories Limited Monohydrate solvates of loracarbef

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502663A (en) * 1969-04-21 1970-03-24 Lilly Co Eli Crystalline cephalosporin,method for its manufacture
US3531481A (en) * 1969-04-21 1970-09-29 Lilly Co Eli Method for manufacture of crystalline cephalosporin
US4775751A (en) * 1985-06-03 1988-10-04 Eli Lilly & Company Process for cephalexin hydrochloride alcoholates
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate
CA2002597C (en) * 1988-11-14 1999-03-23 Thomas M. Eckrich Solvates of b-lactam antibiotic
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
US5374719A (en) * 1993-06-04 1994-12-20 Eli Lilly And Company Process for converting loracarbef dihydrate to loracarbef monohydrate
US5352782A (en) * 1993-06-04 1994-10-04 Eli Lilly And Company Process for preparing crystalline β-lactam monohydrate
US5399686A (en) * 1993-06-04 1995-03-21 Eli Lilly And Company Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate

Also Published As

Publication number Publication date
PL322111A1 (en) 1998-01-05
IL117228A0 (en) 1996-06-18
JPH11501032A (ja) 1999-01-26
TW330205B (en) 1998-04-21
SI0729959T1 (en) 1999-12-31
AU694639B2 (en) 1998-07-23
MX9706606A (es) 1997-11-29
DK0729959T3 (da) 1999-12-13
CO4700429A1 (es) 1998-12-29
KR19980702666A (ko) 1998-08-05
ZA961341B (en) 1997-08-20
AU5174296A (en) 1996-09-18
NZ304534A (en) 1998-09-24
RU2160261C2 (ru) 2000-12-10
DE69603995D1 (de) 1999-10-07
PE28097A1 (es) 1997-08-20
IL117228A (en) 2000-12-06
CZ272897A3 (cs) 1998-01-14
ATE184006T1 (de) 1999-09-15
CN1182429A (zh) 1998-05-20
CA2213812A1 (en) 1996-09-06
AR002709A1 (es) 1998-04-29
BR9607308A (pt) 1997-11-25
NO308471B1 (no) 2000-09-18
US5580977A (en) 1996-12-03
TR199700877T1 (xx) 1998-02-21
ES2135165T3 (es) 1999-10-16
WO1996026942A1 (en) 1996-09-06
HUP9702151A3 (en) 2001-01-29
DE69603995T2 (de) 2000-01-20
CN1061349C (zh) 2001-01-31
NO973835D0 (no) 1997-08-20
EP0729959A1 (en) 1996-09-04
EP0729959B1 (en) 1999-09-01
HUP9702151A2 (hu) 1998-07-28
GR3031947T3 (en) 2000-03-31

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