NO974618L - Farmasöytiske preparater for intranasal administrasjon - Google Patents

Farmasöytiske preparater for intranasal administrasjon

Info

Publication number
NO974618L
NO974618L NO974618A NO974618A NO974618L NO 974618 L NO974618 L NO 974618L NO 974618 A NO974618 A NO 974618A NO 974618 A NO974618 A NO 974618A NO 974618 L NO974618 L NO 974618L
Authority
NO
Norway
Prior art keywords
intranasal administration
pharmaceutical preparations
mixture
powder
composition comprises
Prior art date
Application number
NO974618A
Other languages
English (en)
Other versions
NO974618D0 (no
Inventor
Mitsuko Takenaga
Hiroshi Muramatsu
Tetsuji Ehata
Yasuo Kosaka
Muramatsu Hiroshi
Original Assignee
Fuji Yakuhin Kogyo Kk
Tetsuji Ehata
Igarashi Toshisato
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fuji Yakuhin Kogyo Kk, Tetsuji Ehata, Igarashi Toshisato filed Critical Fuji Yakuhin Kogyo Kk
Publication of NO974618D0 publication Critical patent/NO974618D0/no
Publication of NO974618L publication Critical patent/NO974618L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Det tillveiebringes et farmasøytisk preparat for intranasal administrering og med bedre absorpsjonsevne og mindre irritasjonseffekter. Det farmasøytiske preparat omfatter en blanding av et pulver av en adsorberende harpiks og et biologisk aktivt peptid med medikamenteffekt, under den betingelse at de er tørre før eller etter blandingen.
NO974618A 1996-10-07 1997-10-06 Farmasöytiske preparater for intranasal administrasjon NO974618L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8282866A JP3020141B2 (ja) 1996-10-07 1996-10-07 経鼻投与用製剤

Publications (2)

Publication Number Publication Date
NO974618D0 NO974618D0 (no) 1997-10-06
NO974618L true NO974618L (no) 1998-04-08

Family

ID=17658107

Family Applications (1)

Application Number Title Priority Date Filing Date
NO974618A NO974618L (no) 1996-10-07 1997-10-06 Farmasöytiske preparater for intranasal administrasjon

Country Status (16)

Country Link
US (1) US5948749A (no)
JP (1) JP3020141B2 (no)
KR (1) KR19980032364A (no)
CN (1) CN1180569A (no)
AU (1) AU3992697A (no)
CA (1) CA2217409A1 (no)
DE (1) DE19740733A1 (no)
DK (1) DK114797A (no)
ES (1) ES2126536B1 (no)
FI (1) FI973244L (no)
FR (1) FR2754453A1 (no)
GB (1) GB2322077A (no)
GR (1) GR970100333A (no)
IT (1) IT1295047B1 (no)
NO (1) NO974618L (no)
SE (1) SE9703133L (no)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
WO2000012063A1 (en) * 1998-08-26 2000-03-09 Teijin Limited Powdery pernasal compositions
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1207167B1 (en) * 1999-06-30 2006-10-04 Takeda Pharmaceutical Company Limited Process for the preparation of lh-rh derivatives
US6382204B1 (en) 1999-10-14 2002-05-07 Becton Dickinson And Company Drug delivery system including holder and drug container
USD463546S1 (en) 1999-10-14 2002-09-24 Becton Dickinson And Company Drug container holder
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US20040126900A1 (en) * 2001-04-13 2004-07-01 Barry Stephen E High affinity peptide- containing nanoparticles
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
US20080260838A1 (en) * 2003-08-01 2008-10-23 Mannkind Corporation Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
WO2004073729A1 (ja) 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
US7812120B2 (en) 2003-03-21 2010-10-12 Par Pharmaceutical, Inc. Nasal calcitonin formulations containing chlorobutanol
CA2519287A1 (en) 2003-03-27 2004-10-14 Bioactis Limited Powder medicine applicator for nasal cavity
WO2006016530A1 (ja) * 2004-08-10 2006-02-16 Translational Research, Ltd. 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
US7115561B2 (en) * 2004-09-22 2006-10-03 Patterson James A Medicament composition and method of administration
FR2880272A1 (fr) * 2005-01-04 2006-07-07 Jean Marc Ruiz Preparation contenant des microparticules d'un sel de polymere insoluble portant un principe actif, ainsi que son procede de fabrication
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US20080033038A1 (en) * 2006-07-07 2008-02-07 Shytle R D Compositions of polyphenols and methods of use
CN101668544B (zh) 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
EP2211842B1 (en) * 2007-10-24 2015-08-12 MannKind Corporation An inhalable dry powder formulation comprising glp-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration
CN101827626B (zh) 2008-06-13 2015-03-18 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
US9101539B2 (en) * 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
KR102584844B1 (ko) 2009-06-12 2023-10-04 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
GB2472327B (en) * 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
CN103638527A (zh) * 2013-12-05 2014-03-19 浙江大学 促红细胞生成素载药纳米粒及其应用
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
CN106362158A (zh) * 2015-07-25 2017-02-01 于杰 增效药物
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB792544A (en) * 1956-05-07 1958-03-26 American Home Prod Therapeutic composition
JPS4917563B1 (no) * 1970-12-28 1974-05-01
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
JPS62223131A (ja) * 1986-03-26 1987-10-01 Nitto Electric Ind Co Ltd 持続性鼻疾患治療剤
US5112804A (en) * 1987-04-01 1992-05-12 Temple University Of The Commonwealth System Of Higher Education Pharmaceutical composition and method of intranasal administration
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
US5554388A (en) * 1989-02-25 1996-09-10 Danbiosyst Uk Limited Systemic drug delivery compositions comprising a polycationi substance
GB8904370D0 (en) * 1989-02-25 1989-04-12 Cosmas Damian Ltd Liquid delivery compositions
US5342922A (en) * 1989-03-08 1994-08-30 Washington University Inhibitors of retroviral protease
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
US5397771A (en) * 1990-05-10 1995-03-14 Bechgaard International Research And Development A/S Pharmaceutical preparation
GB9203769D0 (en) * 1992-02-21 1992-04-08 Sandoz Ltd Improvements in or relating to organic compounds
CA2115444C (en) * 1992-06-12 2000-10-03 Yuji Makino Preparation for intratracheobronchial administration
AU678389B2 (en) * 1992-09-10 1997-05-29 Teijin Limited 4-hydroxy-2-cyclopentenone derivative and carcinostatic and osteogenesis promoter containing the same
CA2114830C (en) * 1993-02-05 2000-06-06 Masayasu Tabe Lactone compound and process of production thereof
JP3098401B2 (ja) * 1995-07-12 2000-10-16 株式会社エルティーティー研究所 経鼻投与用製剤

Also Published As

Publication number Publication date
ITMI972144A1 (it) 1999-03-22
JP3020141B2 (ja) 2000-03-15
FI973244A7 (fi) 1998-04-08
FI973244A0 (fi) 1997-08-06
FI973244L (fi) 1998-04-08
DE19740733A1 (de) 1998-04-09
KR19980032364A (ko) 1998-07-25
CN1180569A (zh) 1998-05-06
JPH10114645A (ja) 1998-05-06
SE9703133L (sv) 1998-04-08
CA2217409A1 (en) 1998-04-07
IT1295047B1 (it) 1999-04-27
DK114797A (da) 1998-04-08
GR970100333A (el) 1998-06-30
FR2754453A1 (fr) 1998-04-17
AU3992697A (en) 1998-04-09
SE9703133D0 (sv) 1997-08-29
NO974618D0 (no) 1997-10-06
ES2126536A1 (es) 1999-03-16
ES2126536B1 (es) 1999-10-01
US5948749A (en) 1999-09-07
GB9718690D0 (en) 1997-11-12
GB2322077A (en) 1998-08-19

Similar Documents

Publication Publication Date Title
NO974618L (no) Farmasöytiske preparater for intranasal administrasjon
AU5159490A (en) Composition and method for administration of pharmaceutically active substances
SE8504945L (sv) Farmaceutiska kompositioner innehallande antracyklinglykosider
CA2258095A1 (en) Tetrahydrolipstatin containing compositions
WO2002051390A3 (en) Amphiphilic lipid nanoparticles for peptide and/or protein incorporation
IL116674A (en) Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
AU1534699A (en) Osmotic dosage form comprising first and second coats
AU5806998A (en) Processes for spray drying solutions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
FI953898A7 (fi) Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita
ES2009216A6 (es) Metodo de preparar un derivado de interleucina-lalfa.
ATE217532T1 (de) Eine didemnin verbindung enthaltende pharmazeutische formulierung
FR2577557B1 (fr) Peptides et derives peptidiques, leur preparation, leur utilisation en therapeutique et compositions pharmaceutiques les contenant
CA2087543A1 (en) Heterocyclic compounds
SE8701479L (sv) Metod foer inneslutning av biologiskt verksamma preparat samt anvaendning daerav
HUP9903353A3 (en) 7alpha-(methyl-amino-pentyl)-estratrienes, pharmaceutical preparations which contain said 7alpha-(5-methylaminopentyl) -estratrienes and use thereof for production of drugs
HUP9904210A3 (en) Analogues of camptothecin,their application as medicine and pharmaceutical compositions containing them
AU6804394A (en) Oral pharmaceutical compositions comprising a protein or peptide, an antibody and polymeric beads
WO1991003226A3 (en) Pharmaceutical compositions containing aromatic polymers and therapeutic methods using the same
GEP20022735B (en) Pharmaceutical Compositions Containing Lamivudine and Zidovudine
KR900701300A (ko) 생물학적 활성 펩티드 및 특정음이온을 갖는 조성물 및 이것을 사용하는 방법
EP0409893A4 (en) Magnetically influenced homeopathic pharmaceutical formulations, methods of their preparation and methods of their administration
NO305792B1 (no) Substituerte benzensulfonylureaer, deres anvendelse for fremstilling av farmas°ytiske preparater og medikamenter inneholdende disse
DK0483320T3 (da) Farmaceutiske sammensætninger med forlænget frigivelse til peroral indgivelse og fremgangsmåde til fremstilling deraf
FI940717A0 (fi) Streptogramiinien puhdistetut muodot, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet
FR2756285B1 (fr) Derives de n-(imidazolylbutyle)benzenesulfonamide, leur preparation et leur application en therapeutique