NO974779L - FremgangsmÕte for separasjon av en blanding av enantiomere - Google Patents
FremgangsmÕte for separasjon av en blanding av enantiomereInfo
- Publication number
- NO974779L NO974779L NO974779A NO974779A NO974779L NO 974779 L NO974779 L NO 974779L NO 974779 A NO974779 A NO 974779A NO 974779 A NO974779 A NO 974779A NO 974779 L NO974779 L NO 974779L
- Authority
- NO
- Norway
- Prior art keywords
- enantiomers
- diastereomer
- mixture
- optically active
- active form
- Prior art date
Links
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/023—Preparation; Separation; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/80—Preparation of compounds containing amino groups bound to a carbon skeleton by photochemical reactions; by using free radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/34—Preparation of optical isomers by separation of optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1004346A NL1004346C2 (nl) | 1996-10-23 | 1996-10-23 | Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO974779D0 NO974779D0 (no) | 1997-10-16 |
| NO974779L true NO974779L (no) | 1998-04-24 |
Family
ID=19763731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO974779A NO974779L (no) | 1996-10-23 | 1997-10-16 | FremgangsmÕte for separasjon av en blanding av enantiomere |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6235927B1 (de) |
| EP (1) | EP0838448B1 (de) |
| JP (1) | JPH10245368A (de) |
| CN (1) | CN1182068A (de) |
| AT (1) | ATE264826T1 (de) |
| CA (1) | CA2218804A1 (de) |
| DE (1) | DE69728730T9 (de) |
| IL (1) | IL122012A (de) |
| IN (1) | IN184142B (de) |
| NL (1) | NL1004346C2 (de) |
| NO (1) | NO974779L (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999042460A1 (en) * | 1998-02-20 | 1999-08-26 | Fine Chemicals Corporation (Proprietary) Limited | Process for the production of optically enriched (r)- or (s)-albuterol |
| US6713627B2 (en) | 1998-03-13 | 2004-03-30 | Aventis Pharmaceuticals Inc. | Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol |
| NL1008911C2 (nl) * | 1998-04-17 | 1999-10-19 | Dsm Nv | Werkwijze voor het verhogen van de enantiomere overmaat van een chirale verbinding. |
| EP1034826A1 (de) | 1999-03-05 | 2000-09-13 | Reuter Chemische Apparatebau | Co-Kristallisationsverfahren |
| NL1012865C2 (nl) * | 1999-08-19 | 2001-02-20 | Dsm Nv | 1-Fenyl-3-oxopropaan-1-sulfonzuren en -sulfonaten en zuivere enantiomeren daarvan. |
| WO2001030763A1 (en) * | 1999-10-22 | 2001-05-03 | Takeda Chemical Industries, Ltd. | Process for producing optically active naphthalene derivative and optical resolver therefor |
| US7666588B2 (en) * | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
| JP2005104895A (ja) * | 2003-09-30 | 2005-04-21 | Nippon Kayaku Co Ltd | 光学活性なアミノアルコール化合物の製造法 |
| ATE361905T1 (de) * | 2003-12-10 | 2007-06-15 | Degussa | Verfahren zur herstellung von enantiomeren angereicherten aminosäuren |
| EP1720861A2 (de) | 2004-02-25 | 2006-11-15 | Eli Lilly And Company | Antagonisten des histamin-h3-rezeptors, herstellung und therapeutische anwendungen |
| WO2006006071A1 (en) * | 2004-07-07 | 2006-01-19 | Pfizer Products Inc. | Resolution of an aryl-fused azapolycyclic compound |
| EP1885692A2 (de) * | 2005-05-04 | 2008-02-13 | Medichem, S.A. | Verfahren zur herstellung von tamsulosin |
| MX2007016216A (es) | 2005-07-01 | 2008-03-11 | Lilly Co Eli | Agenes del receptor de histamina h3, preparacion y usos terapeuticos. |
| ES2393757T3 (es) | 2005-11-17 | 2012-12-27 | Eli Lilly & Company | Antagonistas de receptor de glucagón, preparación y usos terapéuticos |
| WO2007114855A2 (en) | 2005-11-18 | 2007-10-11 | Eli Lilly And Company | Glucagon receptor antagonists, preparation and therapeutic uses |
| UA99284C2 (ru) | 2007-05-11 | 2012-08-10 | Елі Ліллі Енд Компані | ИНГИБИТОРЫ р70 S6-КИНАЗЫ |
| BRPI0916197B1 (pt) | 2008-07-29 | 2018-01-23 | Poxel | Processo para isolar componentes enantioméricos de uma mistura de enantiômeros |
| AR075988A1 (es) | 2009-04-09 | 2011-05-11 | Lilly Co Eli | Compuesto de piridiloxi - pirrolidina inhibidor de recaptacion de serotonina y norepinefrina, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para el tratamiento de dolor cronico |
| EA020151B1 (ru) | 2009-10-23 | 2014-09-30 | Эли Лилли Энд Компани | Ингибиторы akt и фармацевтические составы, их содержащие |
| CN101792398B (zh) * | 2010-03-09 | 2013-06-26 | 河北科技大学 | 一种拆分法制备光学纯对羟基苯甘氨酸的方法 |
| CN104876856B (zh) * | 2015-05-05 | 2017-11-21 | 河北凯力昂生物科技有限公司 | 一种拆分法制备(r)‑(+)‑3‑氨基哌啶二盐酸盐的方法 |
| CN104829459B (zh) * | 2015-05-06 | 2017-05-24 | 河北凯力昂生物科技有限公司 | 一种拆分法制备(r)‑(+)‑1‑萘乙胺的方法 |
| KR102565407B1 (ko) * | 2016-01-04 | 2023-08-10 | (주)아모레퍼시픽 | 극성 비양자성 용매를 이용한 n-[4-(1-아미노에틸)-페닐]-술폰아미드 유도체의 카이랄 분할 방법 |
| CN108658784B (zh) * | 2018-04-26 | 2020-12-18 | 联化科技股份有限公司 | (r)-1-(4-甲基苯基)乙胺的合成方法 |
| CN109485561A (zh) * | 2018-11-23 | 2019-03-19 | 江苏颖盛化工有限公司 | 一种dl-萘普生的合成工艺 |
| WO2021074778A1 (en) * | 2019-10-16 | 2021-04-22 | Hikal Limited | An industrial process for resolution of chlocyphos |
| US20260015329A1 (en) * | 2022-07-14 | 2026-01-15 | Kureha Corporation | Method for producing triazole derivative enantiomer (r) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB656500A (en) * | 1947-10-24 | 1951-08-22 | Sterling Drug Inc | Improvements in or relating to the preparation of l-arterenol and l-arterenol so prepared |
| US3862985A (en) * | 1971-07-28 | 1975-01-28 | Allied Chem | Resolution of lysineamide |
| WO1985003932A1 (en) * | 1984-03-01 | 1985-09-12 | Alkaloida Vegyészeti Gyár | Novel diastereomer salts of phenylalanine and n-acyl derivatives thereof and process for the separation of optically active phenylalanine and n-acyl derivatives thereof |
-
1996
- 1996-10-23 NL NL1004346A patent/NL1004346C2/nl not_active IP Right Cessation
-
1997
- 1997-10-16 NO NO974779A patent/NO974779L/no not_active Application Discontinuation
- 1997-10-20 DE DE69728730T patent/DE69728730T9/de active Active
- 1997-10-20 EP EP97203262A patent/EP0838448B1/de not_active Expired - Lifetime
- 1997-10-20 AT AT97203262T patent/ATE264826T1/de not_active IP Right Cessation
- 1997-10-20 IN IN2350MA1997 patent/IN184142B/en unknown
- 1997-10-21 CA CA002218804A patent/CA2218804A1/en not_active Abandoned
- 1997-10-21 IL IL12201297A patent/IL122012A/xx not_active IP Right Cessation
- 1997-10-22 US US08/955,612 patent/US6235927B1/en not_active Expired - Fee Related
- 1997-10-23 CN CN97122879A patent/CN1182068A/zh active Pending
- 1997-10-23 JP JP9326871A patent/JPH10245368A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL1004346C2 (nl) | 1998-04-24 |
| CA2218804A1 (en) | 1998-04-23 |
| ATE264826T1 (de) | 2004-05-15 |
| DE69728730D1 (de) | 2004-05-27 |
| EP0838448B1 (de) | 2004-04-21 |
| IL122012A (en) | 2001-08-26 |
| US6235927B1 (en) | 2001-05-22 |
| IN184142B (de) | 2000-06-17 |
| JPH10245368A (ja) | 1998-09-14 |
| DE69728730T9 (de) | 2005-09-08 |
| DE69728730T2 (de) | 2005-03-31 |
| IL122012A0 (en) | 1998-03-10 |
| NO974779D0 (no) | 1997-10-16 |
| CN1182068A (zh) | 1998-05-20 |
| EP0838448A1 (de) | 1998-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |