NO982238L - Substituerte 4-(1H-benzimidazol-2-yl-amino)piperidiner som er anvendbare for behandling av allergiske sykdommer - Google Patents
Substituerte 4-(1H-benzimidazol-2-yl-amino)piperidiner som er anvendbare for behandling av allergiske sykdommerInfo
- Publication number
- NO982238L NO982238L NO982238A NO982238A NO982238L NO 982238 L NO982238 L NO 982238L NO 982238 A NO982238 A NO 982238A NO 982238 A NO982238 A NO 982238A NO 982238 L NO982238 L NO 982238L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- useful
- benzimidazol
- amino
- substituted
- Prior art date
Links
- 208000026935 allergic disease Diseases 0.000 title 1
- CLPYDQPFQYNIDH-UHFFFAOYSA-N n-piperidin-4-yl-1h-benzimidazol-2-amine Chemical class C1CNCCC1NC1=NC2=CC=CC=C2N1 CLPYDQPFQYNIDH-UHFFFAOYSA-N 0.000 title 1
- 206010049153 Allergic sinusitis Diseases 0.000 abstract 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 229940122236 Histamine receptor antagonist Drugs 0.000 abstract 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 208000036284 Rhinitis seasonal Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002462 tachykinin receptor antagonist Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56041995A | 1995-11-17 | 1995-11-17 | |
| US73450896A | 1996-10-17 | 1996-10-17 | |
| PCT/US1996/018001 WO1997019074A1 (en) | 1995-11-17 | 1996-11-07 | Substituted 4-(1h-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO982238D0 NO982238D0 (no) | 1998-05-15 |
| NO982238L true NO982238L (no) | 1998-07-01 |
Family
ID=27072328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO982238A NO982238L (no) | 1995-11-17 | 1998-05-15 | Substituerte 4-(1H-benzimidazol-2-yl-amino)piperidiner som er anvendbare for behandling av allergiske sykdommer |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0920425B1 (no) |
| JP (1) | JPH11513991A (no) |
| KR (1) | KR19990067622A (no) |
| CN (1) | CN1098264C (no) |
| AT (1) | ATE232858T1 (no) |
| AU (1) | AU703701B2 (no) |
| CA (1) | CA2237971C (no) |
| DE (1) | DE69626321T2 (no) |
| DK (1) | DK0920425T3 (no) |
| ES (1) | ES2188801T3 (no) |
| HU (1) | HUP9900927A3 (no) |
| IL (1) | IL124396A (no) |
| MX (1) | MX9803815A (no) |
| NO (1) | NO982238L (no) |
| NZ (1) | NZ323543A (no) |
| PT (1) | PT920425E (no) |
| SI (1) | SI0920425T1 (no) |
| TW (1) | TW394771B (no) |
| WO (1) | WO1997019074A1 (no) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| US5861417A (en) * | 1996-12-19 | 1999-01-19 | Hoechst Marion Roussel, Inc. | Heterocyclic substituted pyrrolidine amide derivatives |
| CA2275527C (en) * | 1996-12-19 | 2003-09-23 | Hoechst Marion Roussel, Inc. | Novel heterocyclic substituted pyrrolidine amide derivatives |
| EP1035869A1 (en) * | 1997-03-26 | 2000-09-20 | Sepracor, Inc. | Chemically and thermally stable norastemizole formulations |
| US6713627B2 (en) | 1998-03-13 | 2004-03-30 | Aventis Pharmaceuticals Inc. | Processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol |
| PE20020507A1 (es) | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| CN100360130C (zh) * | 2002-04-18 | 2008-01-09 | 先灵公司 | 用作组胺h3拮抗剂的1－(4－哌啶基)苯并咪唑酮 |
| EP1747198B1 (en) | 2004-05-07 | 2008-06-04 | Janssen Pharmaceutica N.V. | Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| CA2565630C (en) | 2004-05-07 | 2013-05-28 | Janssen Pharmaceutica N.V. | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| DE602005017159D1 (de) | 2004-08-30 | 2009-11-26 | Janssen Pharmaceutica Nv | Oxysteroid-dehydrogenase-inhibitoren |
| MY141198A (en) | 2004-08-30 | 2010-03-31 | Janssen Pharmaceutica Nv | Tricyclic adamantylamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
| CN101300005B (zh) | 2004-08-30 | 2013-05-01 | 詹森药业有限公司 | 作为11-β羟类固醇脱氢酶抑制剂的N-2金刚烷基-2-苯氧基-乙酰胺衍生物 |
| US8093268B2 (en) | 2007-01-24 | 2012-01-10 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl-benzyl)-(2S-phenylpiperidin-3S-yl-) |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| IL293481A (en) * | 2019-12-06 | 2022-08-01 | Celgene Corp | Processes for the preparation of 2-(4-chlorophenyl)-n-((2-(2,6-dioxypyridin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| FR2719311B1 (fr) * | 1994-03-18 | 1998-06-26 | Sanofi Sa | Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic. |
| CN1067385C (zh) * | 1994-08-25 | 2001-06-20 | 默里尔药物公司 | 用于治疗变应性疾病的新的取代的哌啶类化合物 |
| ATE205102T1 (de) * | 1994-09-23 | 2001-09-15 | Tranas Rostfria Ab | Ein zusammenbau zum praktizieren des gehens |
| CA2162786A1 (en) * | 1994-11-22 | 1996-05-23 | Philip Arthur Hipskind | Heterocyclic tachykinin receptor antagonists |
-
1996
- 1996-11-07 WO PCT/US1996/018001 patent/WO1997019074A1/en not_active Ceased
- 1996-11-07 PT PT96941334T patent/PT920425E/pt unknown
- 1996-11-07 DE DE69626321T patent/DE69626321T2/de not_active Expired - Fee Related
- 1996-11-07 AT AT96941334T patent/ATE232858T1/de not_active IP Right Cessation
- 1996-11-07 CA CA002237971A patent/CA2237971C/en not_active Expired - Fee Related
- 1996-11-07 AU AU10508/97A patent/AU703701B2/en not_active Ceased
- 1996-11-07 EP EP96941334A patent/EP0920425B1/en not_active Expired - Lifetime
- 1996-11-07 CN CN96198360A patent/CN1098264C/zh not_active Expired - Fee Related
- 1996-11-07 HU HU9900927A patent/HUP9900927A3/hu unknown
- 1996-11-07 SI SI9630597T patent/SI0920425T1/xx unknown
- 1996-11-07 NZ NZ323543A patent/NZ323543A/xx unknown
- 1996-11-07 ES ES96941334T patent/ES2188801T3/es not_active Expired - Lifetime
- 1996-11-07 JP JP9519767A patent/JPH11513991A/ja not_active Abandoned
- 1996-11-07 IL IL12439696A patent/IL124396A/xx not_active IP Right Cessation
- 1996-11-07 DK DK96941334T patent/DK0920425T3/da active
- 1996-11-07 KR KR1019980703649A patent/KR19990067622A/ko not_active Abandoned
- 1996-12-20 TW TW085115760A patent/TW394771B/zh not_active IP Right Cessation
-
1998
- 1998-05-13 MX MX9803815A patent/MX9803815A/es unknown
- 1998-05-15 NO NO982238A patent/NO982238L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW394771B (en) | 2000-06-21 |
| WO1997019074A1 (en) | 1997-05-29 |
| DE69626321T2 (de) | 2003-08-14 |
| NZ323543A (en) | 1999-06-29 |
| KR19990067622A (ko) | 1999-08-25 |
| SI0920425T1 (en) | 2003-08-31 |
| CN1202894A (zh) | 1998-12-23 |
| IL124396A0 (en) | 1998-12-06 |
| EP0920425B1 (en) | 2003-02-19 |
| EP0920425A1 (en) | 1999-06-09 |
| MX9803815A (es) | 1998-09-30 |
| IL124396A (en) | 2001-03-19 |
| JPH11513991A (ja) | 1999-11-30 |
| CA2237971C (en) | 2002-01-22 |
| ES2188801T3 (es) | 2003-07-01 |
| HUP9900927A2 (hu) | 2000-03-28 |
| HK1018065A1 (en) | 1999-12-10 |
| HUP9900927A3 (en) | 2002-02-28 |
| DK0920425T3 (da) | 2003-05-26 |
| DE69626321D1 (de) | 2003-03-27 |
| AU703701B2 (en) | 1999-04-01 |
| CN1098264C (zh) | 2003-01-08 |
| PT920425E (pt) | 2003-07-31 |
| ATE232858T1 (de) | 2003-03-15 |
| AU1050897A (en) | 1997-06-11 |
| CA2237971A1 (en) | 1997-05-29 |
| NO982238D0 (no) | 1998-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |