NO983090L - Terapeutiske forbindelser - Google Patents

Terapeutiske forbindelser

Info

Publication number
NO983090L
NO983090L NO983090A NO983090A NO983090L NO 983090 L NO983090 L NO 983090L NO 983090 A NO983090 A NO 983090A NO 983090 A NO983090 A NO 983090A NO 983090 L NO983090 L NO 983090L
Authority
NO
Norway
Prior art keywords
therapeutic compounds
relates
benzimidazole derivatives
prophylaxis
preparation
Prior art date
Application number
NO983090A
Other languages
English (en)
Other versions
NO983090D0 (no
Inventor
Stanley Dawes Chamberlain
George Walter Koszalka
Jeffrey H Tidwell
Nanine Agneta Van Draanen
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO983090D0 publication Critical patent/NO983090D0/no
Publication of NO983090L publication Critical patent/NO983090L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår benzimidazolderivater og deres anvendelse i medisinsk terapi, spesielt for behandlingen eller profylakse av virus- infeksjoner, f.eks. de som er forårsaket av herpes-virus. Oppfinnelsen angår også fremstillingen av benzimidazolderivatene og farmasøytiske preparater som inneholder disse.
NO983090A 1996-01-05 1998-07-03 Terapeutiske forbindelser NO983090L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9600143.3A GB9600143D0 (en) 1996-01-05 1996-01-05 Therapeutic compounds
PCT/GB1996/003151 WO1997025337A1 (en) 1996-01-05 1996-12-19 Therapeutic compounds

Publications (2)

Publication Number Publication Date
NO983090D0 NO983090D0 (no) 1998-07-03
NO983090L true NO983090L (no) 1998-09-01

Family

ID=10786611

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983090A NO983090L (no) 1996-01-05 1998-07-03 Terapeutiske forbindelser

Country Status (21)

Country Link
US (2) US6204249B1 (no)
EP (1) EP0876389A1 (no)
JP (1) JP2000515119A (no)
KR (1) KR19990077041A (no)
CN (1) CN1214049A (no)
AP (1) AP9801286A0 (no)
AU (1) AU729541B2 (no)
BR (1) BR9612413A (no)
CA (1) CA2241993A1 (no)
CZ (1) CZ212698A3 (no)
EA (1) EA001770B1 (no)
GB (1) GB9600143D0 (no)
HU (1) HUP9904301A3 (no)
IS (1) IS4789A (no)
MX (1) MX9805441A (no)
NO (1) NO983090L (no)
NZ (1) NZ324380A (no)
OA (1) OA10707A (no)
PL (1) PL327732A1 (no)
TR (1) TR199801289T2 (no)
WO (1) WO1997025337A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0845001B1 (en) * 1995-08-18 2002-11-13 The Regents of The University of Michigan 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
GB9600143D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
AU6221998A (en) * 1997-02-13 1998-09-08 Glaxo Group Limited Benzimidazole derivatives
CA2281927C (en) 1997-02-25 2004-01-27 Christopher J. Michejda Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase
AU744176B2 (en) 1997-07-30 2002-02-14 Glaxo Group Limited Lyxofuranosyl benzimidazoles as antiviral agents
GB9807354D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB9807355D0 (en) * 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB0008939D0 (en) 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
ES2377937T3 (es) * 2003-12-26 2012-04-03 Kissei Pharmaceutical Co., Ltd. Derivados de benzimidazol y usos médicos de los mismos
JPWO2009044886A1 (ja) 2007-10-05 2011-02-10 株式会社エーピーアイ コーポレーション リボフラノース誘導体の製造方法
US12043644B2 (en) * 2020-06-23 2024-07-23 Biometrix Technology Inc Benzimidazole derivatives, preparation method thereof and use thereof as anti-cancer agent or anti-virus agent comprising the same
CN119136799A (zh) 2022-10-12 2024-12-13 武田药品工业株式会社 制备马立巴韦的方法
WO2024103979A1 (zh) * 2022-11-17 2024-05-23 北京凯因科技股份有限公司 一种抑制疱疹病毒的化合物
CN119119151A (zh) * 2024-09-04 2024-12-13 斯坦德药典标准物质研发(湖北)有限公司 一种马立巴韦的制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE130030C (no)
US3399987A (en) 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3655901A (en) 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
US4002623A (en) 1974-08-07 1977-01-11 Pfizer Inc. Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines
FR2551442B1 (fr) 1983-09-05 1987-04-30 Centre Nat Rech Scient Nouveaux derives furaniques, leur preparation et leur application
EP0304624A3 (de) 1987-07-29 1989-03-22 F. Hoffmann-La Roche Ag Benzimidazol-2-yl-pyridiniumverbindungen
IT1226100B (it) 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
SE9003151D0 (sv) 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1992018517A1 (en) 1991-04-17 1992-10-29 Yale University Method of treating or preventing hepatitis b virus
ZA923640B (en) 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
GB9205071D0 (en) 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
WO1994008456A1 (en) * 1992-10-21 1994-04-28 The Regents Of The University Of Michigan Polysubstituted benzimidazoles as antiviral agents
GB9226879D0 (en) 1992-12-23 1993-02-17 Iaf Biochem Int Anti-viral compounds
US5399580A (en) 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
EP0845001B1 (en) 1995-08-18 2002-11-13 The Regents of The University of Michigan 5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
GB9600143D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
US5995610A (en) * 1997-05-06 1999-11-30 Telefonaktiebolaget Lm Ericsson Cooperative call processing across public and private intelligent networks

Also Published As

Publication number Publication date
CN1214049A (zh) 1999-04-14
MX9805441A (es) 1998-11-30
CA2241993A1 (en) 1997-07-17
EA199800526A1 (ru) 1999-04-29
AP9801286A0 (en) 1998-09-30
PL327732A1 (en) 1998-12-21
HUP9904301A2 (hu) 2000-05-28
KR19990077041A (ko) 1999-10-25
US6617315B1 (en) 2003-09-09
BR9612413A (pt) 1999-07-13
EA001770B1 (ru) 2001-08-27
JP2000515119A (ja) 2000-11-14
NO983090D0 (no) 1998-07-03
TR199801289T2 (en) 1998-10-21
WO1997025337A1 (en) 1997-07-17
HUP9904301A3 (en) 2001-07-30
NZ324380A (en) 2000-01-28
CZ212698A3 (cs) 1998-12-16
OA10707A (en) 2001-05-09
AU1164097A (en) 1997-08-01
US6204249B1 (en) 2001-03-20
AU729541B2 (en) 2001-02-01
IS4789A (is) 1998-06-30
EP0876389A1 (en) 1998-11-11
GB9600143D0 (en) 1996-03-06

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