NO985304L - FremgangsmÕte og sammensetning for rekonformering av multiepitopiske antigener for Õ initiere en immunrespons - Google Patents

FremgangsmÕte og sammensetning for rekonformering av multiepitopiske antigener for Õ initiere en immunrespons

Info

Publication number
NO985304L
NO985304L NO985304A NO985304A NO985304L NO 985304 L NO985304 L NO 985304L NO 985304 A NO985304 A NO 985304A NO 985304 A NO985304 A NO 985304A NO 985304 L NO985304 L NO 985304L
Authority
NO
Norway
Prior art keywords
immune response
antigen
composition
multiepitopic
reconstituting
Prior art date
Application number
NO985304A
Other languages
English (en)
Other versions
NO321511B1 (no
NO985304D0 (no
Inventor
Ragupathy Madiyalakan
Antoine A Noujaim
Richard P Baum
Birgit Schultes
Original Assignee
Altarex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altarex Inc filed Critical Altarex Inc
Publication of NO985304L publication Critical patent/NO985304L/no
Publication of NO985304D0 publication Critical patent/NO985304D0/no
Publication of NO321511B1 publication Critical patent/NO321511B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19985304A 1996-05-15 1998-11-13 Sammensetning for rekonformering av multi-epitopiske antigener for a initiere en immunrespons og anvendelse av sammensetningen til fremstilling av et legemiddel NO321511B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB1996/000461 WO1997042973A1 (en) 1996-05-15 1996-05-15 Method and composition for reconforming multi-epitopic antigens to initiate an immune response

Publications (3)

Publication Number Publication Date
NO985304L true NO985304L (no) 1998-11-13
NO985304D0 NO985304D0 (no) 1998-11-13
NO321511B1 NO321511B1 (no) 2006-05-15

Family

ID=46171074

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19985304A NO321511B1 (no) 1996-05-15 1998-11-13 Sammensetning for rekonformering av multi-epitopiske antigener for a initiere en immunrespons og anvendelse av sammensetningen til fremstilling av et legemiddel
NO20061203A NO20061203L (no) 1996-05-15 2006-03-15 Fremgangsmate og sammensetning for rekontormering av multiepitopiske antigener for a initiere en immunrespons

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20061203A NO20061203L (no) 1996-05-15 2006-03-15 Fremgangsmate og sammensetning for rekontormering av multiepitopiske antigener for a initiere en immunrespons

Country Status (17)

Country Link
US (7) US6241985B1 (no)
EP (2) EP1297846A1 (no)
JP (1) JP3565351B2 (no)
KR (1) KR20020011137A (no)
AT (1) ATE233102T1 (no)
BR (1) BR9612619A (no)
CA (1) CA2253602A1 (no)
DE (1) DE69626423T2 (no)
DK (1) DK0910407T3 (no)
ES (1) ES2193240T3 (no)
HU (1) HUP9903770A3 (no)
IL (1) IL126803A (no)
NO (2) NO321511B1 (no)
NZ (3) NZ505174A (no)
PT (1) PT910407E (no)
SI (1) SI0910407T1 (no)
WO (1) WO1997042973A1 (no)

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US20060159688A1 (en) * 1996-05-15 2006-07-20 Ragupathy Madiyalakan Method for diagnosing efficacy of xenotypic antibody therapy
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EP1085902A2 (en) * 1998-06-15 2001-03-28 AltaRex Medical Corp. Therapeutic compositions that produce an immune response by altering the antigen
US6716966B1 (en) 1999-08-18 2004-04-06 Altarex Corp. Therapeutic binding agents against MUC-1 antigen and methods for their use
ATE290879T1 (de) * 1999-08-18 2005-04-15 Altarex Medical Corp Therapeutische antikörper gegen das muc-1 antigen und verfahren zu deren verwendung
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AU2002256168B2 (en) * 2001-04-10 2007-09-20 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic and diagnostic uses of antibody specificity profiles
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US20050260208A1 (en) * 2002-04-11 2005-11-24 Altarex Medical Corp. Binding agents and their use in targeting tumor cells
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US20090226367A1 (en) * 2005-03-11 2009-09-10 Euro-Celtique S.A. Compositions comprising an anti-ca125 antibody and a cytotoxic compound and their use for the treatment of cancer
WO2007016340A2 (en) * 2005-07-29 2007-02-08 Providence Health System Defective ribosomal products in blebs (dribbles) and methods of use to stimulate an immune response
CA2623329A1 (en) * 2005-10-13 2007-04-19 Virexx Medical Corp. Chimeric antigen containing hepatitis c virus polypeptide and fc fragment for eliciting an immune response
JP2007320969A (ja) * 2007-09-10 2007-12-13 Altarex Medical Corp 免疫応答を惹起するための、多数エピトープ含有抗原の再構成法および組成物

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Also Published As

Publication number Publication date
NO321511B1 (no) 2006-05-15
HUP9903770A3 (en) 2001-07-30
NZ332588A (en) 2000-11-24
US20070036798A1 (en) 2007-02-15
EP1297846A1 (en) 2003-04-02
DE69626423T2 (de) 2004-03-18
PT910407E (pt) 2003-07-31
US20080131443A1 (en) 2008-06-05
ATE233102T1 (de) 2003-03-15
SI0910407T1 (en) 2003-10-31
EP0910407B1 (en) 2003-02-26
JP3565351B2 (ja) 2004-09-15
NZ516264A (en) 2002-04-26
JPH11509558A (ja) 1999-08-24
AU711270B2 (en) 1999-10-07
US20010036457A1 (en) 2001-11-01
EP0910407A1 (en) 1999-04-28
US6086873A (en) 2000-07-11
DE69626423D1 (de) 2003-04-03
WO1997042973A1 (en) 1997-11-20
NZ505174A (en) 2002-03-01
DK0910407T3 (da) 2003-06-16
IL126803A (en) 2003-11-23
US6241985B1 (en) 2001-06-05
AU5658096A (en) 1997-12-05
IL126803A0 (en) 1999-08-17
HUP9903770A2 (hu) 2000-03-28
NO20061203L (no) 1998-11-13
US20080311127A1 (en) 2008-12-18
BR9612619A (pt) 1999-07-20
KR20020011137A (ko) 2002-02-07
US20080206318A1 (en) 2008-08-28
ES2193240T3 (es) 2003-11-01
CA2253602A1 (en) 1997-11-20
NO985304D0 (no) 1998-11-13

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