NO990583D0 - Cykliske eterforbindelser som natriumkanalmodulatorer - Google Patents

Cykliske eterforbindelser som natriumkanalmodulatorer

Info

Publication number
NO990583D0
NO990583D0 NO990583A NO990583A NO990583D0 NO 990583 D0 NO990583 D0 NO 990583D0 NO 990583 A NO990583 A NO 990583A NO 990583 A NO990583 A NO 990583A NO 990583 D0 NO990583 D0 NO 990583D0
Authority
NO
Norway
Prior art keywords
substituted
sodium channel
lower alkyl
cyclic ether
ether compounds
Prior art date
Application number
NO990583A
Other languages
English (en)
Norwegian (no)
Other versions
NO990583L (no
Inventor
Shigenori Ohkawa
Tadatoshi Hashimoto
Kohji Fukatsu
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO990583D0 publication Critical patent/NO990583D0/no
Publication of NO990583L publication Critical patent/NO990583L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transmitters (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
NO990583A 1996-08-29 1999-02-08 Cykliske eterforbindelser som natriumkanalmodulatorer NO990583L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22884596 1996-08-29
JP8649697 1997-04-04
PCT/JP1997/003007 WO1998008842A1 (en) 1996-08-29 1997-08-28 Cyclic ether compounds as sodium channel modulators

Publications (2)

Publication Number Publication Date
NO990583D0 true NO990583D0 (no) 1999-02-08
NO990583L NO990583L (no) 1999-02-08

Family

ID=26427602

Family Applications (1)

Application Number Title Priority Date Filing Date
NO990583A NO990583L (no) 1996-08-29 1999-02-08 Cykliske eterforbindelser som natriumkanalmodulatorer

Country Status (10)

Country Link
US (1) US6172085B1 (de)
EP (1) EP0923575B1 (de)
CN (1) CN1076022C (de)
AT (1) ATE234298T1 (de)
AU (1) AU4031697A (de)
CA (1) CA2264231A1 (de)
DE (1) DE69719766T2 (de)
HU (1) HUP9903557A2 (de)
NO (1) NO990583L (de)
WO (1) WO1998008842A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1136477E (pt) 1998-12-04 2004-08-31 Takeda Chemical Industries Ltd Derivados do benzofurano processo para a sua preparacao e suas utilizacoes
AU4334900A (en) 1999-04-09 2000-11-14 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
WO2001078709A2 (en) * 2000-04-12 2001-10-25 Minerva Biotechnologies Corporation Treatment of neurodegenerative disease
US6825201B2 (en) * 2001-04-25 2004-11-30 Bristol-Myers Squibb Company Indole, azaindole and related heterocyclic amidopiperazine derivatives
CN1274306C (zh) 2001-09-03 2006-09-13 纽朗制药有限公司 包含加巴喷丁或其类似物和α－氨基酰胺的药物组合物及其止痛应用
AU2002363250A1 (en) 2001-11-01 2003-05-12 Icagen, Inc. Pyrazole-amides and-sulfonamides
JP2005514412A (ja) * 2001-12-27 2005-05-19 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 中枢神経系疾患を処置するために有用なアロイルピロールヘテロアリールおよびメタノール類
US20030236277A1 (en) 2002-02-14 2003-12-25 Kadow John F. Indole, azaindole and related heterocyclic pyrrolidine derivatives
AU2003219933A1 (en) 2002-02-25 2003-09-09 Vanderbilt University Expression system for human brain-specific voltage-gated sodium channel, type 1
US7037913B2 (en) 2002-05-01 2006-05-02 Bristol-Myers Squibb Company Bicyclo 4.4.0 antiviral derivatives
US7465815B2 (en) * 2003-06-26 2008-12-16 Takeda Pharmaceutical Company Limited Cannabinoid receptor modulator
EP1783121A4 (de) * 2004-08-27 2009-08-05 Takeda Pharmaceutical Azoverbindungen und verfahren zu deren herstellung
US20060100209A1 (en) * 2004-11-09 2006-05-11 Chong-Hui Gu Formulations of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US20060100432A1 (en) * 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
DE102004061593A1 (de) 2004-12-21 2006-06-22 Abbott Gmbh & Co. Kg Substituierte N-heterocyclische Verbindungen und ihre therapeutische Verwendung
US7598380B2 (en) * 2005-08-03 2009-10-06 Bristol-Myers Squibb Company Method of preparation of azaindole derivatives
WO2007021941A2 (en) 2005-08-16 2007-02-22 Icagen, Inc. Inhibitors of voltage-gated sodium channels
JP2009514868A (ja) 2005-11-02 2009-04-09 イカジェン インコーポレイテッド イオンチャネルの阻害剤
US7851476B2 (en) * 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) * 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
CL2008000835A1 (es) * 2007-03-23 2008-10-03 Icagen Inc Pfizer Ltd Compuestos derivados de sulfonamidas, inhibidores de los canales de calcio; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del dolor, sindrome de intestino irritable, enfermedad de crohn, taquiarritm
JP5460589B2 (ja) * 2007-07-13 2014-04-02 アイカジェン， インコーポレイテッド ナトリウムチャネル阻害物質
CN103554002B (zh) * 2013-10-08 2016-04-27 常州大学 1-苯基吲哚及其制备方法
EP3233077B1 (de) 2014-12-19 2026-05-06 The Broad Institute, Inc. Dopamin-d2-rezeptor-liganden
EP3233799B1 (de) * 2014-12-19 2021-05-19 The Broad Institute, Inc. Dopamin-d2-rezeptor-liganden

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW199152B (de) * 1990-11-01 1993-02-01 Takeda Pharm Industry Co Ltd
JP3198395B2 (ja) * 1992-05-28 2001-08-13 武田薬品工業株式会社 アミノクマラン誘導体
TW334433B (en) 1992-12-09 1998-06-21 Takeda Pharm Industry Co Ltd Crystalline salt of (S)-(+)-5-amino-2,4,6,7-tetramethyl-2-(4-phenylpiperidinomethyl)-2,3-dihydrobenzo(b)furan dihydrochloride their production and use

Also Published As

Publication number Publication date
CA2264231A1 (en) 1998-03-05
DE69719766T2 (de) 2004-01-15
EP0923575B1 (de) 2003-03-12
US6172085B1 (en) 2001-01-09
WO1998008842A1 (en) 1998-03-05
EP0923575A1 (de) 1999-06-23
CN1076022C (zh) 2001-12-12
NO990583L (no) 1999-02-08
AU4031697A (en) 1998-03-19
ATE234298T1 (de) 2003-03-15
DE69719766D1 (de) 2003-04-17
HUP9903557A2 (en) 2002-08-28
CN1223652A (zh) 1999-07-21

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application