NO991012L - 3,6-Ketal- og enoleter-makrolid-antibiotika - Google Patents

3,6-Ketal- og enoleter-makrolid-antibiotika

Info

Publication number
NO991012L
NO991012L NO991012A NO991012A NO991012L NO 991012 L NO991012 L NO 991012L NO 991012 A NO991012 A NO 991012A NO 991012 A NO991012 A NO 991012A NO 991012 L NO991012 L NO 991012L
Authority
NO
Norway
Prior art keywords
ketal
enol ether
macrolide antibiotics
macrolide
antibiotics
Prior art date
Application number
NO991012A
Other languages
English (en)
Other versions
NO991012D0 (no
NO312366B1 (no
Inventor
Peter Bertinato
Hengmiao Cheng
Kristin M Lundby
Road Groton
Subas M Sakya
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO991012D0 publication Critical patent/NO991012D0/no
Publication of NO991012L publication Critical patent/NO991012L/no
Publication of NO312366B1 publication Critical patent/NO312366B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO19991012A 1998-03-03 1999-03-02 3,6-ketal- og enoleter-makrolidforbindelser, anvendelse derav samt farmasöytisk preparat og fremgangsmåte for fremstilling derav NO312366B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7663098P 1998-03-03 1998-03-03

Publications (3)

Publication Number Publication Date
NO991012D0 NO991012D0 (no) 1999-03-02
NO991012L true NO991012L (no) 1999-09-06
NO312366B1 NO312366B1 (no) 2002-04-29

Family

ID=22133253

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19991012A NO312366B1 (no) 1998-03-03 1999-03-02 3,6-ketal- og enoleter-makrolidforbindelser, anvendelse derav samt farmasöytisk preparat og fremgangsmåte for fremstilling derav

Country Status (17)

Country Link
US (1) US6043226A (no)
EP (1) EP0941998B1 (no)
JP (1) JP3666788B2 (no)
CN (1) CN1244532A (no)
AR (1) AR016715A1 (no)
AT (1) ATE275151T1 (no)
AU (1) AU741435B2 (no)
BR (1) BR9900856A (no)
CA (1) CA2263203C (no)
DE (1) DE69919769T2 (no)
DK (1) DK0941998T3 (no)
ES (1) ES2226282T3 (no)
HU (1) HUP9900492A3 (no)
NO (1) NO312366B1 (no)
NZ (1) NZ334442A (no)
PT (1) PT941998E (no)
ZA (1) ZA991664B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
TR200101241T2 (tr) 1998-11-03 2001-09-21 Pfizer Products Inc. Yeni makrolit antibiyotikler
ATE340183T1 (de) 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
US6590083B1 (en) * 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6451768B1 (en) * 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
HUP0201516A3 (en) * 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
AU2001214707A1 (en) * 2000-11-07 2002-05-21 Morphotek Inc. Methods for isolating novel antimicrobial agents from hypermutable mammalian cells
US8063021B2 (en) * 2002-01-17 2011-11-22 Kosan Biosciences Incorporated Ketolide anti-infective compounds
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US20060141470A1 (en) * 2003-02-14 2006-06-29 Kalayoglu Murat V Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
UA85937C2 (uk) 2004-12-21 2009-03-10 Пфайзер Продактс Інк. Макроліди
US7517859B2 (en) * 2005-05-04 2009-04-14 Enanta Pharmaceuticals, Inc. Spirocyclic bicyclolides
EP2203435B1 (en) * 2007-09-17 2018-07-18 Enanta Pharmaceuticals, Inc. 6, 11-bridged biaryl macrolides
GB201706299D0 (en) * 2017-04-20 2017-06-07 Novintum Biotechnology Gmbh Compounds
CA3060892A1 (en) * 2017-04-20 2018-10-25 Rising Tide Foundation Azithromycin derivatives containing a phosphonium ion as anticancer agents
WO2018193111A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as anticancer agents
WO2018193126A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as antibacterial agents
CN110799516A (zh) * 2017-04-20 2020-02-14 来兴泰德基金会 作为抗癌剂的包含鏻离子的阿奇霉素衍生物
WO2018193116A1 (en) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Azithromycin derivatives containing a phosphonium ion as anticancer agents
US11197872B2 (en) 2017-04-21 2021-12-14 Lunella Biotech, Inc. Vitamin C and doxycycline: a synthetic lethal combination therapy for eradicating cancer stem cells (CSCs)
EP3612177A4 (en) 2017-04-21 2021-01-13 Lunella Biotech, Inc. TARGETING HYPOXIC CARCINOUS STEM CELLS (SCC) USING DOXYCYCLINE: IMPLICATIONS FOR IMPROVING ANTI-ANGIOGENIC THERAPY
PH12019502594A1 (en) 2017-05-19 2020-10-26 Lunella Biotech Inc Antimitoscins: targeted inhibitors of mitochondrial biogenesis for eradicating cancer stem cells
CA3063450A1 (en) 2017-05-19 2018-11-22 Lunella Biotech, Inc. Companion diagnostics for mitochondrial inhibitors
KR102854338B1 (ko) 2017-06-26 2025-09-03 루넬라 바이오테크 인코포레이티드 미토케토신: 암 세포에서 케톤 대사를 표적화하는 미토콘드리아-기반의 치료제
GB201817083D0 (en) * 2018-10-19 2018-12-05 Novintum Biotechnology Gmbh Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8721165D0 (en) * 1987-09-09 1987-10-14 Beecham Group Plc Chemical compounds
EP0344106A3 (de) * 1988-05-24 1990-01-31 Ciba-Geigy Ag Blaue Dispersionsfarbstoffe und Mischungen blauer Dispersionsfarbstoffe
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
KR960700258A (ko) * 1993-01-26 1996-01-19 우에하라 아키라 5-0-데소사미닐에리쓰로노라이드 유도체
JP2000509712A (ja) * 1996-05-07 2000-08-02 アボツト・ラボラトリーズ 6―o―置換エリスロマイシン及びその製造方法

Also Published As

Publication number Publication date
NO991012D0 (no) 1999-03-02
PT941998E (pt) 2004-12-31
US6043226A (en) 2000-03-28
BR9900856A (pt) 2000-04-25
JP3666788B2 (ja) 2005-06-29
JPH11315093A (ja) 1999-11-16
EP0941998B1 (en) 2004-09-01
ES2226282T3 (es) 2005-03-16
CA2263203C (en) 2002-09-03
DE69919769T2 (de) 2005-01-27
AU741435B2 (en) 2001-11-29
HUP9900492A2 (hu) 1999-09-28
EP0941998A3 (en) 1999-10-06
DK0941998T3 (da) 2004-09-20
NZ334442A (en) 2000-03-27
CA2263203A1 (en) 1999-09-03
AU1856299A (en) 1999-09-16
DE69919769D1 (de) 2004-10-07
HUP9900492A3 (en) 2001-08-28
ZA991664B (en) 2000-10-12
EP0941998A2 (en) 1999-09-15
ATE275151T1 (de) 2004-09-15
NO312366B1 (no) 2002-04-29
CN1244532A (zh) 2000-02-16
AR016715A1 (es) 2001-07-25
HU9900492D0 (en) 1999-04-28

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