NO991996L - Nukleinsyresekvens som koder for <beta>-C-4-oksygenase fra Haematococcus plivialis for biosyntese av astaxanthin - Google Patents
Nukleinsyresekvens som koder for <beta>-C-4-oksygenase fra Haematococcus plivialis for biosyntese av astaxanthinInfo
- Publication number
- NO991996L NO991996L NO991996A NO991996A NO991996L NO 991996 L NO991996 L NO 991996L NO 991996 A NO991996 A NO 991996A NO 991996 A NO991996 A NO 991996A NO 991996 L NO991996 L NO 991996L
- Authority
- NO
- Norway
- Prior art keywords
- plivialis
- haematococcus
- oxygenase
- beta
- nucleic acid
- Prior art date
Links
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 title 1
- 241000168525 Haematococcus Species 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 title 1
- 229940022405 astaxanthin Drugs 0.000 title 1
- 235000013793 astaxanthin Nutrition 0.000 title 1
- 239000001168 astaxanthin Substances 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/562,535 US5916791A (en) | 1995-11-24 | 1995-11-24 | Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a β--C--4--oxygenase activity for biotechnological production of (3S,3S)astaxanthin |
| US08/742,605 US5965795A (en) | 1995-11-24 | 1996-10-28 | Polynucleotide molecule from Haematococcus pluvialis encoding a polypeptide having a beta-C-4-oxygenase activity for biotechnological production of (3S, 3'S) astaxanthin and its specific expression in chromoplasts of higher plants |
| PCT/US1997/017819 WO1998018910A1 (en) | 1995-11-24 | 1997-10-03 | Nucleic acid sequence encoding beta-c-4-oxygenase from haematococcus pluvialis for the biosynthesis of astaxanthin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO991996D0 NO991996D0 (no) | 1999-04-27 |
| NO991996L true NO991996L (no) | 1999-06-22 |
| NO325046B1 NO325046B1 (no) | 2008-01-21 |
Family
ID=27072985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19991996A NO325046B1 (no) | 1995-11-24 | 1999-04-27 | Nukleinsyresekvens og polypeptid som har beta-karoten-C-4-oksygenase aktivitet, rekombinant vektor og vertscelle, samt fremgangmate for a fremstille xantofyller, transgene planteceller og naeringsmiddeladditiv. |
Country Status (3)
| Country | Link |
|---|---|
| US (4) | US5916791A (no) |
| NO (1) | NO325046B1 (no) |
| WO (1) | WO1998018910A1 (no) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6429356B1 (en) | 1996-08-09 | 2002-08-06 | Calgene Llc | Methods for producing carotenoid compounds, and specialty oils in plant seeds |
| AU732842B2 (en) * | 1996-10-28 | 2001-05-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nucleic acid sequence encoding beta-C-4-oxygenase from haematococcus pluvialis for the biosynthesis of astaxanthin |
| US6653530B1 (en) | 1998-02-13 | 2003-11-25 | Calgene Llc | Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds |
| JP2003527077A (ja) | 1999-04-15 | 2003-09-16 | カルジーン エルエルシー | トコフェロール合成に関与するタンパク質の核酸配列 |
| SE9903336D0 (sv) * | 1999-09-17 | 1999-09-17 | Astacarotene Ab | DNA construct and its use |
| US20030157592A1 (en) * | 1999-12-16 | 2003-08-21 | Jens Lerchl | Moss genes from physcomitrella patens encoding proteins involved in the synthesis of tocopherols and carotenoids |
| US6872815B1 (en) | 2000-10-14 | 2005-03-29 | Calgene Llc | Nucleic acid sequences to proteins involved in tocopherol synthesis |
| US7214520B2 (en) * | 2000-07-18 | 2007-05-08 | National Research Council Of Canada | Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in Escherichia coli |
| AR030124A1 (es) | 2000-08-07 | 2003-08-13 | Monsanto Technology Llc | Genes de la via del fosfato de metil-d-eritritol |
| SK286630B6 (sk) * | 2001-01-22 | 2009-02-05 | Merck & Co., Inc. | Nukleozidové deriváty, farmaceutický prostriedok s ich obsahom a ich použitie |
| US8481712B2 (en) | 2001-01-22 | 2013-07-09 | Merck Sharp & Dohme Corp. | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase |
| CA2436366A1 (en) * | 2001-01-26 | 2002-10-10 | Cargill, Incorporated | Carotenoid biosynthesis |
| US20050003474A1 (en) * | 2001-01-26 | 2005-01-06 | Desouza Mervyn L. | Carotenoid biosynthesis |
| US20040078846A1 (en) * | 2002-01-25 | 2004-04-22 | Desouza Mervyn L. | Carotenoid biosynthesis |
| US7161061B2 (en) | 2001-05-09 | 2007-01-09 | Monsanto Technology Llc | Metabolite transporters |
| DE60230608D1 (de) | 2001-05-09 | 2009-02-12 | Monsanto Technology Llc | Tyra-gene und ihre verwendung |
| US20020177181A1 (en) * | 2001-05-24 | 2002-11-28 | Agricultural Research Organization, The Volcani Center | Increasing bioavailability of carotenoids |
| US7192731B2 (en) * | 2001-05-24 | 2007-03-20 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center | Methods for efficient extraction of carotenoids using an esterase |
| US7252964B2 (en) * | 2001-06-12 | 2007-08-07 | Institut De Recherche Pour Le Developpement (I.R.D.) | Isolated carotenoid biosynthesis gene cluster involved in canthaxanthin production and applications thereof |
| US7575766B2 (en) * | 2001-06-29 | 2009-08-18 | Ball Horticultural Company | Tagetes erecta with altered carotenoid compositions and ratios |
| US7081478B2 (en) * | 2001-06-29 | 2006-07-25 | Chrysantis, Inc. | Mixed zeaxanthin ester concentrate and uses thereof |
| US6784351B2 (en) * | 2001-06-29 | 2004-08-31 | Ball Horticultural Company | Targetes erecta marigolds with altered carotenoid compositions and ratios |
| IL159944A0 (en) * | 2001-07-19 | 2004-06-20 | Yissum Res Dev Co | Polypeptides having carotenoid isomerase catalytic activity, nucleic acids encoding same and uses thereof |
| WO2003016482A2 (en) | 2001-08-17 | 2003-02-27 | Monsanto Technology Llc | Methyltransferase genes and uses thereof |
| WO2003034812A2 (en) | 2001-10-25 | 2003-05-01 | Monsanto Technology Llc | Aromatic methyltransferases and uses thereof |
| US7112717B2 (en) | 2002-03-19 | 2006-09-26 | Monsanto Technology Llc | Homogentisate prenyl transferase gene (HPT2) from arabidopsis and uses thereof |
| US7223909B2 (en) * | 2002-03-21 | 2007-05-29 | Ball Horticultural | 4-ketocarotenoids in flower petals |
| IL164089A0 (en) * | 2002-04-30 | 2005-12-18 | Suntory Ltd | Astaxanthin medium-chain fatty acidester, production method of the same, and composition comprising the same |
| EP1546334A4 (en) | 2002-08-05 | 2007-01-03 | Monsanto Technology Llc | GENES ASSOCIATED WITH TOCOPHEROL BIOSYNTHESIS AND USES THEREOF |
| ATE484198T1 (de) * | 2002-08-20 | 2010-10-15 | Sungene Gmbh & Co Kgaa | Verwendung von astaxanthinhaltigen pflanzen oder pflanzenteilen der gattung tagetes als futtermittel |
| DE102004007622A1 (de) * | 2004-02-17 | 2005-08-25 | Sungene Gmbh & Co. Kgaa | Verfahren zur Herstellung von Ketocarotinoiden in genetisch veränderten, nicht-humanen Organismen |
| AR047658A1 (es) | 2004-02-03 | 2006-02-01 | Cargill Inc | Concentrado de proteinas y corriente acuosa con carbohidratos hidrosolubles |
| WO2005121352A2 (en) * | 2004-06-08 | 2005-12-22 | E.I. Dupont De Nemours And Company | Carotenoid ketolase genes with improved ketocarotenoid yield |
| US7074604B1 (en) * | 2004-12-29 | 2006-07-11 | E. I. Du Pont De Nemours And Company | Bioproduction of astaxanthin using mutant carotenoid ketolase and carotenoid hydroxylase genes |
| GB0501365D0 (en) * | 2005-01-21 | 2005-03-02 | Promar As | Compositions |
| WO2006092449A2 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| CN103589650A (zh) | 2005-03-18 | 2014-02-19 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
| AR058801A1 (es) * | 2005-08-03 | 2008-02-27 | Cargill Inc | Concentrados de proteinas de maiz |
| WO2008042338A2 (en) | 2006-09-28 | 2008-04-10 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| US7434716B2 (en) * | 2006-12-21 | 2008-10-14 | Tyco Healthcare Group Lp | Staple driver for articulating surgical stapler |
| EP2199399A1 (en) | 2008-12-17 | 2010-06-23 | BASF Plant Science GmbH | Production of ketocarotenoids in plants |
| CN101974600A (zh) * | 2010-10-14 | 2011-02-16 | 山东理工大学 | 利用茉莉酸甲酯诱导雨生红球藻生产虾青素的方法 |
| CN101974599B (zh) * | 2010-10-14 | 2011-11-09 | 山东理工大学 | 利用油菜素内酯刺激雨生红球藻快速生产虾青素的方法 |
| CN101974598A (zh) * | 2010-10-14 | 2011-02-16 | 山东理工大学 | 利用茉莉酸促进雨生红球藻生产虾青素的方法 |
| EP2697242B1 (en) | 2011-04-13 | 2018-10-03 | Merck Sharp & Dohme Corp. | 2'-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| BR112013026345A2 (pt) | 2011-04-13 | 2019-04-24 | Merck Sharp & Dohe Corp. | composto, composição farmacêutica, uso de um composto, e, método para tratar um paciente infectado com hcv |
| WO2012142093A2 (en) | 2011-04-13 | 2012-10-18 | Merck Sharp & Dohme Corp. | 2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| US9408863B2 (en) | 2011-07-13 | 2016-08-09 | Merck Sharp & Dohme Corp. | 5′-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases |
| WO2013009735A1 (en) | 2011-07-13 | 2013-01-17 | Merck Sharp & Dohme Corp. | 5'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases |
| CN103805623B (zh) * | 2014-01-17 | 2016-02-03 | 河北大学 | 一种虾青素合成基因重组质粒及其制备方法和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0178871B1 (ko) * | 1994-08-23 | 1999-04-01 | 게이사쿠 마나베 | 케토기 도입 효소, 그를 암호화하는 dna 및 케토카로테노이드를제조하는방법 |
-
1995
- 1995-11-24 US US08/562,535 patent/US5916791A/en not_active Expired - Fee Related
-
1996
- 1996-10-28 US US08/742,605 patent/US5965795A/en not_active Expired - Fee Related
-
1997
- 1997-10-03 WO PCT/US1997/017819 patent/WO1998018910A1/en not_active Ceased
-
1999
- 1999-03-01 US US09/259,294 patent/US6218599B1/en not_active Expired - Fee Related
- 1999-04-27 NO NO19991996A patent/NO325046B1/no unknown
-
2001
- 2001-02-26 US US09/791,687 patent/US6903245B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20020053096A1 (en) | 2002-05-02 |
| NO325046B1 (no) | 2008-01-21 |
| US6218599B1 (en) | 2001-04-17 |
| WO1998018910A1 (en) | 1998-05-07 |
| NO991996D0 (no) | 1999-04-27 |
| US5965795A (en) | 1999-10-12 |
| US5916791A (en) | 1999-06-29 |
| US6903245B2 (en) | 2005-06-07 |
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