NO992225L - FremgangsmÕte for fremstilling av salter og estere av klavulansyre - Google Patents

FremgangsmÕte for fremstilling av salter og estere av klavulansyre

Info

Publication number
NO992225L
NO992225L NO992225A NO992225A NO992225L NO 992225 L NO992225 L NO 992225L NO 992225 A NO992225 A NO 992225A NO 992225 A NO992225 A NO 992225A NO 992225 L NO992225 L NO 992225L
Authority
NO
Norway
Prior art keywords
esters
preparation
clavulanic acid
salts
pharmaceutically acceptable
Prior art date
Application number
NO992225A
Other languages
English (en)
Other versions
NO992225D0 (no
Inventor
Johannes Booij
Antonius Van Den Heuvel
Original Assignee
Gist Brocades Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv
Publication of NO992225D0 publication Critical patent/NO992225D0/no
Publication of NO992225L publication Critical patent/NO992225L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

En forbedret fremgangsmåte for fremstillingen av farmasøytisk akseptable alkalimetallsalter eller estere av klavulansyre er blitt tilveiebrakt. Videre er det også blitt tilveiebrakt kaliumklavulanat med et ekstremt lavt amininnhold og farmasøytiske sammensetninger som inneholder det samme.
NO992225A 1996-11-11 1999-05-07 FremgangsmÕte for fremstilling av salter og estere av klavulansyre NO992225L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96203117 1996-11-11
PCT/EP1997/006263 WO1998021212A1 (en) 1996-11-11 1997-11-10 Process for the preparation of salts and esters of clavulanic acid

Publications (2)

Publication Number Publication Date
NO992225D0 NO992225D0 (no) 1999-05-07
NO992225L true NO992225L (no) 1999-05-07

Family

ID=8224563

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992225A NO992225L (no) 1996-11-11 1999-05-07 FremgangsmÕte for fremstilling av salter og estere av klavulansyre

Country Status (11)

Country Link
EP (1) EP0937084A1 (no)
JP (1) JP2001503763A (no)
CN (1) CN1238776A (no)
AU (1) AU5551698A (no)
BR (1) BR9713339A (no)
CA (1) CA2271847A1 (no)
NO (1) NO992225L (no)
PL (1) PL333247A1 (no)
TR (1) TR199901631T2 (no)
WO (1) WO1998021212A1 (no)
ZA (1) ZA9710141B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT400033B (de) 1992-03-10 1995-09-25 Biochemie Gmbh Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
SI9500134B (sl) * 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
AT403375B (de) * 1995-11-15 1998-01-26 Biochemie Gmbh Verfahren zur fällung von alkalisalzen der clavulansäure
WO2000004028A1 (en) * 1998-07-16 2000-01-27 Dsm N.V. Improved process for the preparation of salts and esters of clavulanic acid
ATE260096T1 (de) * 1999-04-01 2004-03-15 Dsm Ip Assets Bv Agglomerate durch kristallisation
BRPI0110774B8 (pt) * 2000-05-13 2021-05-25 Smithkline Beecham Plc processo para purificação de um sal de ácido clavulânico
CN101548018A (zh) * 2006-12-01 2009-09-30 帝斯曼知识产权资产管理有限公司 一种用于制备克拉维酸的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9300296B (sl) * 1992-06-11 1998-06-30 Smithkline Beecham P.L.C. Postopek in intermedianti za pripravo klavulanske kisline
KR100200239B1 (ko) * 1992-10-21 1999-06-15 김충환 클라불란산 칼륨염의 제조방법
GB9305565D0 (en) * 1993-03-18 1993-05-05 Smithkline Beecham Plc Novel compounds and processes
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) * 1994-12-24 1995-02-22 Spurcourt Ltd Clavulanic acid salts
SI9500074A (en) * 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500134B (sl) * 1995-04-20 2004-04-30 Lek, Postopek za pripravo čistih alkalijskih soli klavulanske kisline
KR100200242B1 (ko) * 1995-05-16 1999-06-15 김충환 클라불란산염의 제조 방법

Also Published As

Publication number Publication date
JP2001503763A (ja) 2001-03-21
CN1238776A (zh) 1999-12-15
PL333247A1 (en) 1999-11-22
ZA9710141B (en) 1998-06-25
NO992225D0 (no) 1999-05-07
EP0937084A1 (en) 1999-08-25
AU5551698A (en) 1998-06-03
BR9713339A (pt) 2000-05-09
TR199901631T2 (xx) 1999-09-21
WO1998021212A1 (en) 1998-05-22
CA2271847A1 (en) 1998-05-22

Similar Documents

Publication Publication Date Title
NO971889L (no) Forbindelser og sammensetninger for levering av aktive midler
AU7035094A (en) New 11-benzaldoxime-estradiene-derivatives, methods for their production and pharmaceuticals containing these substances
AU649421B2 (en) Isoxazole-4-carboxamides and hydroxyalkylidene-cyanoacetamides, drugs containing these compounds and use of such drugs
EP0650483A4 (en) (3r,4r)--g(d)?6 -tetrahydrocannabinol-7-oic acids.
MY114389A (en) Aqueous risperidone formulations
IE851918L (en) An indole derivative.
HK129093A (en) N-tert-butyl-decahydro-2(3-amino-2-hydroxy-4-phenyl-butyl)isoquinoline-3-carboxamide & asparaginyl derivatives thereof
AU3475097A (en) Substituted cyclopentane compounds useful as neuraminidase inhibitors
RU94035686A (ru) 4-ариламино-бензопиран и родственные соединения, фармацевтическая композиция, способ лечения
DK0748387T3 (da) Fremgangsmåde til isolation af clavulansyre og farmaceutisk acceptable salte deraf fra fermenteringsvæsken af Streptomyces sp. P 6621 FERM P 2804
IL127542A0 (en) Administration regimen of H+ K+ -ATPase inhibitors
PL305091A1 (en) Novel derivatives of 11-benzaldoxim-17beta-methoxy-17alpha methoxymethyl estradiene, method of obtaining them and therapeutic agents containing such compounds
DZ2242A1 (fr) Antibiotique carbapenème, compositions et procédé de préparation.
GEP19971030B (en) Method for preparation of derivatives of 1-benzil-3-oximetil-indazolului or salts with pharmaceutically acceptable bases
AU579111B2 (en) Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase
GR3031542T3 (en) Cephalosporinderivatives and process for its preparation
FI945510A0 (fi) Klavulaanihapon diamiinisuolat
IE872667L (en) Pharmaceutical compositions
PL328123A1 (en) Derivatives of banzo[c]quinolysine and method of obtaining them
BG101884A (en) Salts of the clavulanic acid
TR199901631T2 (xx) Klavülanik asitin esterleri ve tuzlarının hazırlanması için işlem.
MY114213A (en) Clavulanic acid salts
AU553874B2 (en) Thiazaspirane derivatives
NO990283L (no) Formulering for behandling og/eller profylakse av demens
AU7028798A (en) Use of 2-methylthiazolidine-2,4-dicarboxylic acid as mucolytic agent

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application