NO992980L - Nitroimidazol gelpreparat - Google Patents
Nitroimidazol gelpreparatInfo
- Publication number
- NO992980L NO992980L NO992980A NO992980A NO992980L NO 992980 L NO992980 L NO 992980L NO 992980 A NO992980 A NO 992980A NO 992980 A NO992980 A NO 992980A NO 992980 L NO992980 L NO 992980L
- Authority
- NO
- Norway
- Prior art keywords
- nitroimidazole
- gel preparation
- water
- skin
- bydroxyalkyl
- Prior art date
Links
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 title abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- -1 alkylene glycol Chemical compound 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 1
- 239000003349 gelling agent Substances 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Colloid Chemistry (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Viskøst hydrogelpreparat for anvendelse ved topisk behandling av en hudlidelse som involverer tørr eller betent hud, om- fattende et antitnikrobielt aktivt nitroimidazolmedikament, et vann-blandbart alkylenglykol, et hydroksyalkylcellulose-gel- dannende middel og vann, bufret til å ha en fysiologisk akseptabel pH, og en fremgangsmåte for fremstilling av dette.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9626513.7A GB9626513D0 (en) | 1996-12-20 | 1996-12-20 | A pharmaceutical composition |
| PCT/GB1997/003512 WO1998027960A2 (en) | 1996-12-20 | 1997-12-19 | A nitroimidazole gel composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO992980D0 NO992980D0 (no) | 1999-06-17 |
| NO992980L true NO992980L (no) | 1999-08-16 |
Family
ID=10804765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO992980A NO992980L (no) | 1996-12-20 | 1999-06-17 | Nitroimidazol gelpreparat |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6348203B1 (no) |
| EP (1) | EP0946143B1 (no) |
| JP (1) | JP2001507018A (no) |
| KR (1) | KR20000069606A (no) |
| AT (1) | ATE323466T1 (no) |
| AU (1) | AU730812B2 (no) |
| CA (1) | CA2275429A1 (no) |
| DE (1) | DE69736998T2 (no) |
| DK (1) | DK0946143T3 (no) |
| ES (1) | ES2263183T3 (no) |
| GB (1) | GB9626513D0 (no) |
| IE (1) | IES970906A2 (no) |
| NO (1) | NO992980L (no) |
| NZ (1) | NZ336258A (no) |
| PT (1) | PT946143E (no) |
| WO (1) | WO1998027960A2 (no) |
| ZA (1) | ZA9711455B (no) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2232855C (en) * | 1997-04-10 | 2007-10-09 | Roche Consumer Health (Worldwide) Sa | Pharmaceutical formulation |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| EP1206937B1 (en) * | 1999-07-16 | 2008-01-23 | Shoei Co., Ltd. | Nitroimidazole external preparations for the treatment of atopic dermatitis |
| JP2002212073A (ja) * | 2001-01-15 | 2002-07-31 | Shoei:Kk | 水性液剤 |
| SE0103528D0 (sv) | 2001-10-21 | 2001-10-21 | Jan Faergeman | Topiska kompositioner med förstärkt effekt |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| SE0301862D0 (sv) * | 2003-06-26 | 2003-06-26 | Jan Faergeman | Sätt att inhibera tillväxten av mot antibiotika resistenta bakterier |
| US7456207B2 (en) * | 2003-09-25 | 2008-11-25 | Teva Pharmaceuticals Usa, Inc. | Vaginal pharmaceutical compositions and methods for preparing them |
| FR2866570B1 (fr) * | 2004-02-20 | 2007-08-24 | Galderma Res & Dev | Utilisation du metronidazole pour la preparation d'une composition pharmaceutique destinee a traiter une inflammation cutanee |
| FR2866569B1 (fr) * | 2004-02-20 | 2007-08-24 | Galderma Res & Dev | Utilisation du metronidazole pour la preparation d'une composition pharmaceutique destinee a traiter des pathologies liees au recepteur de type b de l'interleukine 8 et/ou au recepteur de type 1 de pacap |
| FR2866568B1 (fr) * | 2004-02-20 | 2007-08-24 | Galderma Res & Dev | Utilisation du metronidazole pour la preparation d'une composition pharmaceutique destinee a traiter un desordre de la vascularisation cutanee |
| US20060093675A1 (en) * | 2004-10-29 | 2006-05-04 | Mathew Ebmeier | Intravaginal treatment of vaginal infections with metronidazole compositions |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| KR101106510B1 (ko) | 2006-05-30 | 2012-01-20 | 인타르시아 세라퓨틱스 인코포레이티드 | 투피스, 내부채널 삼투압 전달 시스템 유동 조절기 |
| EP2359808B1 (en) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotic delivery systems and piston assemblies |
| US8258164B2 (en) * | 2006-09-12 | 2012-09-04 | Curatek Pharmaceuticals Holding, Inc. | Nitroimidazole composition and method |
| JP5238295B2 (ja) * | 2007-03-09 | 2013-07-17 | 第一三共ヘルスケア株式会社 | 低刺激性透明半固形外用剤 |
| WO2008133908A2 (en) | 2007-04-23 | 2008-11-06 | Intarcia Therapeutics, Inc. | Suspension formulations of insulinotropic peptides and uses thereof |
| DE102008006394A1 (de) * | 2008-01-28 | 2009-07-30 | Beiersdorf Ag | Verwendung von Wirkstoffkomplexen aus Panthenol, Glycerin, Citrat und/oder Bisabolol gegen Pollenallergien |
| CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| US20100105750A1 (en) * | 2008-10-23 | 2010-04-29 | Nycomed Us Inc. | Stable metronidazole gel formulations |
| RU2547990C2 (ru) | 2009-09-28 | 2015-04-10 | Интарсия Терапьютикс, Инк. | Быстрое достижение и/или прекращение существенной стабильной доставки лекарственного средства |
| CN106913902A (zh) | 2009-11-09 | 2017-07-04 | 聚光灯技术合伙有限责任公司 | 多糖基水凝胶 |
| CN102695501A (zh) | 2009-11-09 | 2012-09-26 | 聚光灯技术合伙有限责任公司 | 碎裂水凝胶 |
| WO2012009794A1 (en) * | 2010-07-19 | 2012-01-26 | Brusells Ventures Corp. | Antimicrobial medical gel composition comprising etherified hydroxyethylcellulose |
| JP5954928B2 (ja) * | 2010-11-19 | 2016-07-20 | 大同化成工業株式会社 | 皮膚潰瘍処置用外用剤のゲル状基剤 |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| AU2012275292B2 (en) | 2011-06-28 | 2015-11-12 | Chemo Research, S.L. | High dosage mucoadhesive metronidazole aqueous-based gel formulations their use to treat bacterial vaginosis |
| WO2014100569A1 (en) * | 2012-12-20 | 2014-06-26 | Medicis Pharmaceutical Corporation | High dosage topical metronidazole gel formulations |
| EP3013368A1 (en) | 2013-06-25 | 2016-05-04 | Mission Pharmacal Company | Novel formulations for the treatment of vaginal disorders |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| RU2730996C2 (ru) | 2015-06-03 | 2020-08-26 | Интарсия Терапьютикс, Инк. | Системы установки и извлечения имплантата |
| AU2016344349B2 (en) * | 2015-10-25 | 2022-05-19 | Iview Therapeutics, Inc. | Pharmaceutical formulations that form gel in situ |
| KR102574993B1 (ko) | 2016-05-16 | 2023-09-06 | 인타르시아 세라퓨틱스 인코포레이티드 | 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법 |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| JP7286542B2 (ja) | 2017-01-03 | 2023-06-05 | インターシア セラピューティクス,インコーポレイティド | Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3421443C2 (de) * | 1984-06-08 | 1996-09-05 | Daicel Chem | Stabile Gelmasse und Verfahren zu ihrer Herstellung |
| US5536743A (en) * | 1988-01-15 | 1996-07-16 | Curatek Pharmaceuticals Limited Partnership | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
| EP0386960A3 (en) * | 1989-03-07 | 1991-10-23 | American Cyanamid Company | Pharmaceutical compositions useful as drug delivery vehicles and/or as wound dressings |
| GB2229443A (en) * | 1989-03-07 | 1990-09-26 | American Cyanamid Co | Wound dressings |
| CA1337279C (en) * | 1989-06-06 | 1995-10-10 | Robert J. Borgman | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
| EP0564586B1 (en) * | 1990-12-21 | 2002-03-20 | BOMBART, Felice | Aqueous vaginal douche and related methods |
| GB9105995D0 (en) * | 1991-03-21 | 1991-05-08 | Smith & Nephew | Wound dressing |
| US5662924A (en) * | 1991-03-21 | 1997-09-02 | Smith & Nephew Plc | Wound dressing |
| SE506509C2 (sv) * | 1992-04-14 | 1997-12-22 | Bioglan Ab | Användning av imidazoler för framställning av en farmaceutisk formulering för behandling av inflammatoriska och/eller infektiösa hudsjukdomar |
| US5391367A (en) * | 1993-07-28 | 1995-02-21 | Pfizer Inc. | Antifungal nail solution |
-
1996
- 1996-12-20 GB GBGB9626513.7A patent/GB9626513D0/en active Pending
-
1997
- 1997-12-19 ES ES97950300T patent/ES2263183T3/es not_active Expired - Lifetime
- 1997-12-19 AU AU53308/98A patent/AU730812B2/en not_active Ceased
- 1997-12-19 DE DE69736998T patent/DE69736998T2/de not_active Expired - Lifetime
- 1997-12-19 NZ NZ336258A patent/NZ336258A/en not_active IP Right Cessation
- 1997-12-19 EP EP97950300A patent/EP0946143B1/en not_active Revoked
- 1997-12-19 WO PCT/GB1997/003512 patent/WO1998027960A2/en not_active Ceased
- 1997-12-19 ZA ZA9711455A patent/ZA9711455B/xx unknown
- 1997-12-19 KR KR1019997005596A patent/KR20000069606A/ko not_active Withdrawn
- 1997-12-19 US US09/331,367 patent/US6348203B1/en not_active Expired - Lifetime
- 1997-12-19 DK DK97950300T patent/DK0946143T3/da active
- 1997-12-19 JP JP52854498A patent/JP2001507018A/ja active Pending
- 1997-12-19 PT PT97950300T patent/PT946143E/pt unknown
- 1997-12-19 CA CA002275429A patent/CA2275429A1/en not_active Abandoned
- 1997-12-19 AT AT97950300T patent/ATE323466T1/de active
- 1997-12-22 IE IE970906A patent/IES970906A2/en not_active IP Right Cessation
-
1999
- 1999-06-17 NO NO992980A patent/NO992980L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE323466T1 (de) | 2006-05-15 |
| ZA9711455B (en) | 1998-09-02 |
| PT946143E (pt) | 2006-08-31 |
| KR20000069606A (ko) | 2000-11-25 |
| AU5330898A (en) | 1998-07-17 |
| EP0946143A2 (en) | 1999-10-06 |
| DE69736998T2 (de) | 2007-03-01 |
| CA2275429A1 (en) | 1998-07-02 |
| GB9626513D0 (en) | 1997-02-05 |
| WO1998027960A2 (en) | 1998-07-02 |
| IES80590B2 (en) | 1998-10-07 |
| JP2001507018A (ja) | 2001-05-29 |
| ES2263183T3 (es) | 2006-12-01 |
| EP0946143B1 (en) | 2006-04-19 |
| AU730812B2 (en) | 2001-03-15 |
| IES970906A2 (en) | 1998-10-07 |
| DE69736998D1 (de) | 2007-01-04 |
| US6348203B1 (en) | 2002-02-19 |
| NO992980D0 (no) | 1999-06-17 |
| DK0946143T3 (da) | 2006-08-21 |
| WO1998027960A3 (en) | 1998-09-11 |
| NZ336258A (en) | 2001-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |