NO993180L - N-(pyridinylamino)isoindoler og beslektede forbindelser - Google Patents
N-(pyridinylamino)isoindoler og beslektede forbindelserInfo
- Publication number
- NO993180L NO993180L NO993180A NO993180A NO993180L NO 993180 L NO993180 L NO 993180L NO 993180 A NO993180 A NO 993180A NO 993180 A NO993180 A NO 993180A NO 993180 L NO993180 L NO 993180L
- Authority
- NO
- Norway
- Prior art keywords
- pyridinylamino
- related compounds
- isoindoles
- intermediates
- isoindolines
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- -1 N- (pyridinylamino) isoindoles Chemical class 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 230000007074 memory dysfunction Effects 0.000 abstract 1
- FRDNVRYBEXCNBP-UHFFFAOYSA-N n-pyridin-2-yl-1,3-dihydroisoindol-2-amine Chemical class C1C2=CC=CC=C2CN1NC1=CC=CC=N1 FRDNVRYBEXCNBP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
- C07D213/77—Hydrazine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77430896A | 1996-12-27 | 1996-12-27 | |
| US08/959,789 US6004977A (en) | 1996-12-27 | 1997-10-29 | N-(pyridinylamino) isoindolines and related compounds |
| PCT/US1997/020591 WO1998029407A2 (en) | 1996-12-27 | 1997-11-13 | N-(pyridinylamino)isoindolines for treating alzheimer's and depression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO993180D0 NO993180D0 (no) | 1999-06-25 |
| NO993180L true NO993180L (no) | 1999-08-26 |
Family
ID=27118867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO993180A NO993180L (no) | 1996-12-27 | 1999-06-25 | N-(pyridinylamino)isoindoler og beslektede forbindelser |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0950056B1 (de) |
| JP (1) | JP4256937B2 (de) |
| KR (1) | KR20000062358A (de) |
| AT (1) | ATE224387T1 (de) |
| AU (1) | AU720466B2 (de) |
| BR (1) | BR9714189A (de) |
| CA (1) | CA2276203C (de) |
| DE (1) | DE69715668T2 (de) |
| DK (1) | DK0950056T3 (de) |
| ES (1) | ES2179377T3 (de) |
| HU (1) | HUP0000783A2 (de) |
| IL (1) | IL130642A0 (de) |
| NO (1) | NO993180L (de) |
| PT (1) | PT950056E (de) |
| WO (1) | WO1998029407A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6772195B1 (en) | 1999-10-29 | 2004-08-03 | Electronic Arts, Inc. | Chat clusters for a virtual world application |
| EP1283199A4 (de) * | 2000-05-16 | 2003-12-17 | Takeda Chemical Industries Ltd | Antagonisten des melanin-konzentrierenden hormons |
| KR20060009686A (ko) * | 2004-07-26 | 2006-02-01 | 엘지이노텍 주식회사 | 반도체 발광소자 및 그 제조방법 |
| US9623021B2 (en) | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| KR101638035B1 (ko) | 2007-01-22 | 2016-07-11 | 지티엑스, 인코포레이티드 | 핵 수용체에 결합하는 물질 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3852335T2 (de) * | 1987-04-24 | 1995-05-11 | Hoechst Roussel Pharma | N-(Pyridinyl)-1H-indol-1-amine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel. |
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
| DK0415103T3 (da) * | 1989-08-02 | 1995-06-19 | Hoechst Roussel Pharma | 2,3-Dihydro-1-(pyridinylamino)-indoler, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler |
| US5102891A (en) * | 1990-07-23 | 1992-04-07 | Hoechst-Roussel Pharmaceuticals Inc. | 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates |
| US5177088A (en) * | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
| US5328920A (en) * | 1991-04-17 | 1994-07-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted (pyridinylamino)-indoles |
-
1997
- 1997-11-13 DE DE69715668T patent/DE69715668T2/de not_active Expired - Fee Related
- 1997-11-13 BR BR9714189-5A patent/BR9714189A/pt not_active IP Right Cessation
- 1997-11-13 CA CA002276203A patent/CA2276203C/en not_active Expired - Fee Related
- 1997-11-13 HU HU0000783A patent/HUP0000783A2/hu unknown
- 1997-11-13 EP EP97948250A patent/EP0950056B1/de not_active Expired - Lifetime
- 1997-11-13 JP JP52999098A patent/JP4256937B2/ja not_active Expired - Fee Related
- 1997-11-13 IL IL13064297A patent/IL130642A0/xx unknown
- 1997-11-13 DK DK97948250T patent/DK0950056T3/da active
- 1997-11-13 AU AU54349/98A patent/AU720466B2/en not_active Ceased
- 1997-11-13 AT AT97948250T patent/ATE224387T1/de not_active IP Right Cessation
- 1997-11-13 PT PT97948250T patent/PT950056E/pt unknown
- 1997-11-13 WO PCT/US1997/020591 patent/WO1998029407A2/en not_active Ceased
- 1997-11-13 ES ES97948250T patent/ES2179377T3/es not_active Expired - Lifetime
- 1997-11-13 KR KR1019997005846A patent/KR20000062358A/ko not_active Abandoned
-
1999
- 1999-06-25 NO NO993180A patent/NO993180L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2276203C (en) | 2003-07-22 |
| WO1998029407A3 (en) | 1998-10-22 |
| IL130642A0 (en) | 2000-06-01 |
| EP0950056A2 (de) | 1999-10-20 |
| ES2179377T3 (es) | 2003-01-16 |
| KR20000062358A (ko) | 2000-10-25 |
| DK0950056T3 (da) | 2003-01-27 |
| DE69715668T2 (de) | 2003-07-31 |
| AU720466B2 (en) | 2000-06-01 |
| CA2276203A1 (en) | 1998-07-09 |
| AU5434998A (en) | 1998-07-31 |
| BR9714189A (pt) | 2000-02-29 |
| NO993180D0 (no) | 1999-06-25 |
| ATE224387T1 (de) | 2002-10-15 |
| PT950056E (pt) | 2002-12-31 |
| HUP0000783A2 (hu) | 2001-04-28 |
| JP2001511119A (ja) | 2001-08-07 |
| EP0950056B1 (de) | 2002-09-18 |
| WO1998029407A2 (en) | 1998-07-09 |
| DE69715668D1 (de) | 2002-10-24 |
| JP4256937B2 (ja) | 2009-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |