NO993438L - Ultrasound contrast agents - Google Patents

Ultrasound contrast agents

Info

Publication number
NO993438L
NO993438L NO993438A NO993438A NO993438L NO 993438 L NO993438 L NO 993438L NO 993438 A NO993438 A NO 993438A NO 993438 A NO993438 A NO 993438A NO 993438 L NO993438 L NO 993438L
Authority
NO
Norway
Prior art keywords
sensitivity
types
contrast agents
microparticle
acoustic energy
Prior art date
Application number
NO993438A
Other languages
Norwegian (no)
Other versions
NO993438D0 (en
Inventor
Jonny Oestensen
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO993438L publication Critical patent/NO993438L/en
Publication of NO993438D0 publication Critical patent/NO993438D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Kontrastmidler til ultralydavbilding som inneholder to eller flere typer gassinneholdende mikropartikler som har forskjellig følsomhet overfor ultralydtrykk. Mikropartikkeltyper med' relativt lav følsomhet overfor ultralydtrykk gir en respons på høy akustisk energi i nærfeltet der mikropartikkeltyper med relativt høy følsomhet har lett for å bli ødelagt. Mikropartikkeltyper med høyere følsomhet er effektive i fjernfeltets miljø med lavere akustisk energi, der mikropartikkeltyper med lavere følsomhet ikke gir særlig respons.Ultrasound imaging contrast agents containing two or more types of gas-containing microparticles having different ultrasound pressure sensitivity. Microparticle types with 'relatively low sensitivity to ultrasound pressure provide a response to high acoustic energy in the near field where microparticle types with relatively high sensitivity are easily destroyed. Higher sensitivity microparticle types are effective in the far field environment with lower acoustic energy, where microparticle types with lower sensitivity give no particular response.

NO993438A 1997-01-22 1999-07-13 Ultrasound contrast agents NO993438D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9701237.1A GB9701237D0 (en) 1997-01-22 1997-01-22 Improvements in or relating to contrast agents
PCT/GB1998/000189 WO1998032468A1 (en) 1997-01-22 1998-01-22 Contrast agents containing two types of gas filled microbubbles

Publications (2)

Publication Number Publication Date
NO993438L true NO993438L (en) 1999-07-13
NO993438D0 NO993438D0 (en) 1999-07-13

Family

ID=10806374

Family Applications (1)

Application Number Title Priority Date Filing Date
NO993438A NO993438D0 (en) 1997-01-22 1999-07-13 Ultrasound contrast agents

Country Status (8)

Country Link
EP (1) EP0966305A1 (en)
JP (1) JP2001508454A (en)
CN (1) CN1244131A (en)
AU (1) AU5674098A (en)
CA (1) CA2278750A1 (en)
GB (1) GB9701237D0 (en)
NO (1) NO993438D0 (en)
WO (1) WO1998032468A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999013916A2 (en) * 1997-09-18 1999-03-25 Nycomed Imaging As Methods and compositions for medical imaging
EP1590006B1 (en) 2003-02-04 2010-09-08 Bracco Suisse SA Ultrasound contrast agents and process for the preparation thereof
CA2547024C (en) 2003-12-22 2013-12-17 Bracco Research Sa Gas-filled microvesicle assembly for contrast imaging
WO2006018433A1 (en) * 2004-08-18 2006-02-23 Bracco Research Sa Gas-filled microvesicles composition for contrast imaging
WO2010010473A1 (en) * 2008-07-23 2010-01-28 Koninklijke Philips Electronics, N.V. Ultrasound mediated drug delivery
US8278418B2 (en) 2008-09-26 2012-10-02 Ambrx, Inc. Modified animal erythropoietin polypeptides and their uses
CN109529033A (en) * 2018-07-09 2019-03-29 彭盛 A kind of stable oxygen carrier microvesicle and its preparation method and application
CN113521317B (en) * 2021-07-01 2023-03-31 中国科学院深圳先进技术研究院 Ultrasonic molecular composite imaging method for double-targeting tumor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585112A (en) * 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
DE4100470A1 (en) * 1991-01-09 1992-07-16 Byk Gulden Lomberg Chem Fab Echo contrast agent
ES2231775T5 (en) * 1993-07-30 2011-02-02 Imcor Pharmaceutical Co. COMPOSITION OF STABILIZED MICROBUBBLES FOR ECOGRAPHY.
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents

Also Published As

Publication number Publication date
CA2278750A1 (en) 1998-07-30
JP2001508454A (en) 2001-06-26
EP0966305A1 (en) 1999-12-29
CN1244131A (en) 2000-02-09
GB9701237D0 (en) 1997-03-12
WO1998032468A1 (en) 1998-07-30
NO993438D0 (en) 1999-07-13
AU5674098A (en) 1998-08-18

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