NO993461L - Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis - Google Patents

Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis

Info

Publication number: NO993461L
Authority: NO; Norway
Prior art keywords: tetrahydrobenz; emesis; carboxamides; indole; drugs
Prior art date: 1993-06-10

Application number

NO993461A

Other languages

English (en)

Other versions

NO308693B1 (no

NO993461D0 (no

Inventor

Mark Mortensen Foreman

J David Leander

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-10

Filing date

1999-07-14

Publication date

1994-12-12

1994-12-12 Publication of NO993461L publication Critical patent/NO993461L/no

1999-07-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-07-14 Publication of NO993461D0 publication Critical patent/NO993461D0/no

2000-10-16 Publication of NO308693B1 publication Critical patent/NO308693B1/no

Links

RTRIOEOJERCNTB-UHFFFAOYSA-N 1,2,2a,3-tetrahydrobenzo[cd]indole-6-carboxamide Chemical class N1CC2CC=CC3=C2C1=CC=C3C(=O)N RTRIOEOJERCNTB-UHFFFAOYSA-N 0.000 title 1
206010047700 Vomiting Diseases 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
230000002265 prevention Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Neurology (AREA)
Pregnancy & Childbirth (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO993461A 1993-06-10 1999-07-14 Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis NO308693B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US7519893A	1993-06-10	1993-06-10

Publications (3)

Publication Number	Publication Date
NO993461L true NO993461L (no)	1994-12-12
NO993461D0 NO993461D0 (no)	1999-07-14
NO308693B1 NO308693B1 (no)	2000-10-16

Family

ID=22124191

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
NO19942143A NO321500B1 (no)	1993-06-10	1994-06-09	Anvendelse av et tetrahydrobenz[cd]indol-6-karboksamid for fremstilling av et medikament for behandling av seksuell dysfunksjon
NO991551A NO991551D0 (no)	1993-06-10	1999-03-30	Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider i fremstilling av medikamenter for forebyggelse av emesis og behandling av seksuell dysfunksjon
NO993461A NO308693B1 (no)	1993-06-10	1999-07-14	Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis
NO20015806A NO20015806D0 (no)	1993-06-10	2001-11-28	Farmasöytisk preparat inneholdende et tetrahydrobenz[c,d]indol-6-karboksamid og anvendelse derav

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
NO19942143A NO321500B1 (no)	1993-06-10	1994-06-09	Anvendelse av et tetrahydrobenz[cd]indol-6-karboksamid for fremstilling av et medikament for behandling av seksuell dysfunksjon
NO991551A NO991551D0 (no)	1993-06-10	1999-03-30	Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider i fremstilling av medikamenter for forebyggelse av emesis og behandling av seksuell dysfunksjon

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20015806A NO20015806D0 (no)	1993-06-10	2001-11-28	Farmasöytisk preparat inneholdende et tetrahydrobenz[c,d]indol-6-karboksamid og anvendelse derav

Country Status (17)

Country	Link
US (1)	US5703112A (no)
EP (2)	EP0633023A3 (no)
JP (1)	JPH0748254A (no)
KR (2)	KR100367792B1 (no)
CN (2)	CN1072932C (no)
AU (1)	AU677317B2 (no)
CA (1)	CA2125088A1 (no)
CZ (2)	CZ285762B6 (no)
HK (1)	HK1043322B (no)
HU (1)	HUT71464A (no)
IL (1)	IL109872A (no)
NO (4)	NO321500B1 (no)
NZ (2)	NZ314570A (no)
RU (1)	RU2154476C2 (no)
TW (1)	TW258660B (no)
UA (2)	UA29415C2 (no)
ZA (1)	ZA943862B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000066114A1 (en)	1999-04-30	2000-11-09	Lilly Icos Llc	Treatment of female arousal disorder
RU2154490C1 (ru) *	1999-07-15	2000-08-20	Кибрик Николай Давидович	Способ лечения сексуальных расстройств диэнцефального генеза у мужчин
GB0106446D0 (en) *	2001-03-15	2001-05-02	Vernalis Res Ltd	Chemical compounds
RU2200556C1 (ru) *	2001-12-05	2003-03-20	Северцев Владимир Алексеевич	Лекарственная форма налтрексона
PL1890684T3 (pl)	2005-06-08	2014-05-30	Sk Biopharmaceuticals Co Ltd	Leczenie zaburzeń snu i czuwania
ES2344469T3 (es) *	2005-06-22	2010-08-27	Sk Holdings Co., Ltd.	Tratamiento de disfuncion sexual.
MX2012000034A (es)	2009-06-22	2012-02-21	Sk Biopharmaceuticals Co Ltd	Metodos para el tratamiento o la prevencion de la fatiga.
EP2496228B1 (en)	2009-11-06	2014-01-15	SK Biopharmaceuticals Co., Ltd.	Methods for treating attention-deficit/hyperactivity disorder
US8927602B2 (en)	2009-11-06	2015-01-06	Sk Biopharmaceuticals Co., Ltd.	Methods for treating fibromyalgia syndrome
US9610274B2 (en)	2010-06-30	2017-04-04	Sk Biopharmaceuticals Co., Ltd.	Methods for treating bipolar disorder
PT2968208T (pt)	2013-03-13	2022-10-28	Aerial Biopharma Llc	Tratamento da cataplexia
US9226910B2 (en)	2013-07-18	2016-01-05	Jazz Pharmaceuticals International Iii Limited	Treatment for obesity
US10195151B2 (en)	2016-09-06	2019-02-05	Jazz Pharmaceuticals International Iii Limited	Formulations of (R)-2-amino-3-phenylpropyl carbamate
BR112019025286A2 (pt)	2017-06-02	2020-06-23	Jazz Pharmaceuticals Ireland Limited	Métodos e composições para tratamento de sonolência excessiva
US10940133B1 (en)	2020-03-19	2021-03-09	Jazz Pharmaceuticals Ireland Limited	Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4110339A (en) *	1977-11-25	1978-08-29	Eli Lilly And Company	4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4521421A (en) *	1983-09-26	1985-06-04	Eli Lilly And Company	Treatment of sexual dysfunction
US4576959A (en) *	1984-02-06	1986-03-18	Eli Lilly And Company	6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) *	1984-05-24	1990-03-06	Carl Kaiser	6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4745126A (en) *	1987-03-12	1988-05-17	Eli Lilly And Company	Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) *	1987-07-10	1990-07-24	Wright State University	Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (de) *	1988-03-18	1989-09-28	Bayer Ag	1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) *	1989-04-11	1993-04-20	Eli Lilly And Company	Tetrahydrobenz(c,d)indole serotonin agonists
WO1991000856A2 (en) *	1989-07-13	1991-01-24	The Upjohn Company	(1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
US5302612A (en) *	1990-02-26	1994-04-12	Eli Lilly And Company	6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) *	1990-02-26	1996-10-31	Lilly Co Eli	6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
AU639536B2 (en) *	1990-03-15	1993-07-29	Pharmacia & Upjohn Company	Therapeutically useful heterocyclic indole compounds
US5096908A (en) *	1990-05-04	1992-03-17	Eli Lilly And Company	Method of inhibiting gastric acid secretion
US5258379A (en) *	1990-05-04	1993-11-02	Eli Lilly And Company	Method of inhibiting gastric acid secretion with n-arylpiperazines
US5229409A (en) *	1990-08-15	1993-07-20	Eli Lilly And Company	6-substituted-tetrahydrobenz[cd]indoles
US5244912A (en) *	1991-03-28	1993-09-14	Eli Lilly And Company	6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof

1994
- 1994-06-02 NZ NZ314570A patent/NZ314570A/xx unknown
- 1994-06-02 ZA ZA943862A patent/ZA943862B/xx unknown
- 1994-06-02 CZ CZ941354A patent/CZ285762B6/cs not_active IP Right Cessation
- 1994-06-02 NZ NZ260667A patent/NZ260667A/en unknown
- 1994-06-02 CZ CZ982818A patent/CZ285829B6/cs not_active IP Right Cessation
- 1994-06-02 IL IL10987294A patent/IL109872A/xx not_active IP Right Cessation
- 1994-06-03 CA CA002125088A patent/CA2125088A1/en not_active Abandoned
- 1994-06-04 TW TW083105103A patent/TW258660B/zh active
- 1994-06-06 UA UA94005243A patent/UA29415C2/uk unknown
- 1994-06-07 EP EP94304103A patent/EP0633023A3/en not_active Withdrawn
- 1994-06-07 EP EP01201582A patent/EP1166783A3/en not_active Withdrawn
- 1994-06-08 AU AU64607/94A patent/AU677317B2/en not_active Ceased
- 1994-06-08 KR KR1019940012778A patent/KR100367792B1/ko not_active Expired - Fee Related
- 1994-06-09 JP JP6127646A patent/JPH0748254A/ja active Pending
- 1994-06-09 RU RU94020717/14A patent/RU2154476C2/ru not_active IP Right Cessation
- 1994-06-09 CN CN94106467A patent/CN1072932C/zh not_active Expired - Fee Related
- 1994-06-09 NO NO19942143A patent/NO321500B1/no unknown
- 1994-06-09 HU HU9401730A patent/HUT71464A/hu unknown
1995
- 1995-11-17 US US08/560,174 patent/US5703112A/en not_active Expired - Fee Related
1999
- 1999-03-30 NO NO991551A patent/NO991551D0/no unknown
- 1999-07-14 NO NO993461A patent/NO308693B1/no unknown
2000
- 2000-06-27 UA UA2000063803A patent/UA37311C2/uk unknown
- 2000-10-31 CN CNB00132828XA patent/CN1170536C/zh not_active Expired - Fee Related
2001
- 2001-11-28 NO NO20015806A patent/NO20015806D0/no unknown
2002
- 2002-07-12 HK HK02105194.1A patent/HK1043322B/zh not_active IP Right Cessation
- 2002-08-31 KR KR1020020052257A patent/KR100367791B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU6460794A (en)	1994-12-15
NO942143L (no)	1994-12-12
AU677317B2 (en)	1997-04-17
NO321500B1 (no)	2006-05-15
CN1072932C (zh)	2001-10-17
TW258660B (no)	1995-10-01
JPH0748254A (ja)	1995-02-21
UA37311C2 (uk)	2001-05-15
NO991551D0 (no)	1999-03-30
NZ260667A (en)	1997-05-26
NO20015806D0 (no)	2001-11-28
CA2125088A1 (en)	1994-12-11
HK1043322A1 (en)	2002-09-13
EP1166783A3 (en)	2002-01-09
KR100367791B1 (ko)	2003-02-14
EP1166783A2 (en)	2002-01-02
CZ285829B6 (cs)	1999-11-17
RU2154476C2 (ru)	2000-08-20
EP0633023A2 (en)	1995-01-11
EP0633023A3 (en)	1995-03-29
KR950000146A (ko)	1995-01-03
HUT71464A (en)	1995-11-28
CN1342457A (zh)	2002-04-03
NO991551L (no)	1994-12-12
ZA943862B (en)	1995-12-04
UA29415C2 (uk)	2000-11-15
HU9401730D0 (en)	1994-09-28
NO308693B1 (no)	2000-10-16
RU94020717A (ru)	1996-08-27
CN1100634A (zh)	1995-03-29
KR100367792B1 (ko)	2003-02-19
CN1170536C (zh)	2004-10-13
IL109872A (en)	2000-12-06
CZ135494A3 (en)	1994-12-15
HK1043322B (zh)	2005-06-03
IL109872A0 (en)	1994-10-07
NZ314570A (en)	2000-11-24
US5703112A (en)	1997-12-30
NO20015806L (no)	1994-12-12
NO942143D0 (no)	1994-06-09
NO993461D0 (no)	1999-07-14
CZ285762B6 (cs)	1999-11-17

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NO993461D0 (no)	1999-07-14	Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis
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FI930700A0 (fi)	1993-02-17	Anordningar foer avlaegsnande av goedsel
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FI931228A0 (fi)	1993-03-19	Foerfarande foer framstaellning av karboxylsyraklorider av aromatiska kvaeve-heterocykliska foereningar
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NO903964D0 (no)	1990-09-11	Anordning for hindring av sykkeltyveri.
FI930088A0 (fi)	1993-01-11	Urinsamlare foer underlaettande av provtagning fraon barn
FI931797A0 (fi)	1993-04-21	Anordning foer stoedande av dragfordon
NO880435L (no)	1989-08-02	Fremgangsmaate for inhibering av frigivelsen av histamin.
FI933968A0 (fi)	1993-09-10	Anordning foer hindrande av stoeld av skidor
FI1218U1 (fi)	1994-02-21	Anordning foer foeljandet av en patients vitalfunktioner
FIU940319U0 (fi)	1994-06-02	Anordning avsedd foer insaettning av en intra-uterin ring